2026 ICD-10-CM Diagnosis Code T44.0X1APoisoning by anticholinesterase agents, accidental (unintentional), initial encounter
T44.0X1A is a billable ICD-10-CM diagnosis code for poisoning by anticholinesterase agents, accidental (unintentional), initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. Coders also document this condition as accidental anticholinesterase overdose. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, accidental/unintentional; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Accidental anticholinesterase overdose
- Accidental poisoning by anticholinesterase
- Accidental poisoning by cholinergic
- Anticholinesterase overdose
- Poisoning by anticholinesterase
- Poisoning by organophosphorus anticholinesterase
- Poisoning by reversible anticholinesterase
Coding GuidelinesGuidance
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Edrophonium
a rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. it has also been used as an antidote to curare principles.Galantamine
a benzazepine derived from norbelladine. it is found in galanthus and other amaryllidaceae. it is a cholinesterase inhibitor that has been used to reverse the muscular effects of gallamine triethiodide and tubocurarine and has been studied as a treatment for alzheimer disease and other central nervous system disorders.Isoflurophate
a di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the nervous system.Pyridostigmine Bromide
a cholinesterase inhibitor with a slightly longer duration of action than neostigmine. it is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Tacrine
a cholinesterase inhibitor that crosses the blood-brain barrier. tacrine has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of alzheimer's disease and other central nervous system disorders.
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
Patient EducationClinical
Medication Errors
Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T44.0X1A to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T44.0X1AOverview
Is T44.0X1A a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by anticholinesterase agents, accidental (unintentional), initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character A in T44.0X1A mean?
The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by anticholinesterase agents, accidental (unintentional), such as an emergency visit or first evaluation.
What MS-DRG does T44.0X1A group to?
When poisoning by anticholinesterase agents, accidental (unintentional), initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of T44.0X1A?
Under the General Equivalence Mappings, poisoning by anticholinesterase agents, accidental (unintentional), initial encounter converts to ICD-9-CM 971.0 (pois-parasympathomimetic) and E855.3 (acc poison-cholinergics). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
