2026 ICD-10-CM Diagnosis Code T43.653SPoisoning by methamphetamines, assault, sequela

ICD-10-CM Codes›S00–T88›T36-T50›T43

ICD-10-CM T43.653S
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T43.653S is a billable ICD-10-CM diagnosis code for poisoning by methamphetamines, assault, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Mental and substance use disorders; sequela; and Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T43.653S
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by methamphetamines, assault, sequela
Short Description
Poisoning by methamphetamines, assault, sequela
Same as the full description in the CMS dataset.
Parent Code
T43.653
Poisoning by methamphetamines, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT43Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
This CodeT43.653SPoisoning by methamphetamines, assault, sequela

Present on Admission (POA)Billing

T43.653S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (T43). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MBD034
Mental and substance use disorders; sequela
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Methamphetamine

    a central nervous system stimulant and sympathomimetic with actions and uses similar to dextroamphetamine. the smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect		Under­dosing
DesoxyephedrineT43.651T43.652T43.653T43.654T43.655T43.656
MetamfetamineT43.651T43.652T43.653T43.654T43.655T43.656
MethamphetamineT43.651T43.652T43.653T43.654T43.655T43.656
MethedrineT43.651T43.652T43.653T43.654T43.655T43.656
MethylamphetamineT43.651T43.652T43.653T43.654T43.655T43.656
SpeedT43.651T43.652T43.653T43.654T43.655T43.656

Code History & ChangesHistory

Replacement T43.653S replaces the following previously assigned code(s):

  • T43.623S - Poisoning by amphetamines, assault, sequela
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T43.653SOverview

Is T43.653S (Poisoning by methamphetamines, assault) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by methamphetamines, assault, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T43.653S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by methamphetamines, assault itself has resolved, not the original event.

What MS-DRG does T43.653S group to?

When poisoning by methamphetamines, assault, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T43.653S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by methamphetamines, assault, sequela on inpatient claims.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.