2026 ICD-10-CM Diagnosis Code T43.643APoisoning by ecstasy, assault, initial encounter

ICD-10-CM CodesS00–T88T36-T50T43

ICD-10-CM T43.643A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T43.643A is a billable ICD-10-CM diagnosis code for poisoning by ecstasy, assault, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, assault; External cause codes: poisoning by drug; and Hallucinogen-related disorders.

Code Identity

ICD-10-CM Code
T43.643A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by ecstasy, assault, initial encounter
Short Description
Poisoning by ecstasy, assault, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Poisoning by ecstasy, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT43Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
This CodeT43.643APoisoning by ecstasy, assault, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (T43). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT022
External cause codes: intent of injury, assault
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD022
Hallucinogen-related disorders
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR MBD021
Stimulant-related disorders
Default principal diagnosis: inpatient No · outpatient No

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
3,4-methylenedioxymethamphetamineT43.641T43.642T43.643T43.644
EcstasyT43.641T43.642T43.643T43.644
MDMAT43.641T43.642T43.643T43.644
MethylenedioxymethamphetamineT43.641T43.642T43.643T43.644

Patient EducationClinical

Club Drugs

Club drugs are a group of psychoactive drugs. They act on the central nervous system and can cause changes in mood, awareness, and behavior. These drugs are most often used by young adults at bars, concerts, nightclubs, and parties.

The full article covers:

  • What are club drugs?
  • What are the different types of club drugs?
  • What are date rape drugs?
  • Are there steps I can take to protect myself from date rape drugs?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement T43.643A replaces the following previously assigned code(s):

  • T43.623A - Poisoning by amphetamines, assault, initial encounter
FY 2019AddedAdded to the ICD-10-CM code setEffective October 1, 2018.
FY 2020–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T43.643AOverview

Is T43.643A (Poisoning by ecstasy, assault) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by ecstasy, assault, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T43.643A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by ecstasy, assault, such as an emergency visit or first evaluation.

What MS-DRG does T43.643A group to?

When poisoning by ecstasy, assault, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.