2026 ICD-10-CM Diagnosis Code T43.3X3APoisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter

ICD-10-CM CodesS00–T88T36-T50T43

ICD-10-CM T43.3X3A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T43.3X3A is a billable ICD-10-CM diagnosis code for poisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, assault; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T43.3X3A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter
Short Description
Poisoning by phenothiaz antipsychot/neurolept, assault, init
Parent Code
Poisoning by phenothiazine antipsychotics and neuroleptics, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT43Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
This CodeT43.3X3APoisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (T43). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT022
External cause codes: intent of injury, assault
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Acepromazine

    a phenothiazine that is used in the treatment of psychoses.
  • Chlorpromazine

    the prototypical phenothiazine antipsychotic drug. like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
  • Fluphenazine

    a phenothiazine used in the treatment of psychoses. its properties and uses are generally similar to those of chlorpromazine.
  • Mesoridazine

    a phenothiazine antipsychotic with effects similar to chlorpromazine.
  • Methotrimeprazine

    a phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. it has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (from martindale, the extra pharmacopoeia, 30th ed, p604)
  • Perazine

    a phenothiazine antipsychotic with actions and uses similar to those of chlorpromazine. extrapyramidal symptoms may be more common than other side effects.
  • Perphenazine

    an antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine.
  • Prochlorperazine

    a phenothiazine antipsychotic used principally in the treatment of nausea; vomiting; and vertigo. it is more likely than chlorpromazine to cause extrapyramidal disorders. (from martindale, the extra pharmacopoeia, 30th ed, p612)
  • Promazine

    a phenothiazine with actions similar to chlorpromazine but with less antipsychotic activity. it is primarily used in short-term treatment of disturbed behavior and as an antiemetic.
  • Thiethylperazine

    a dopamine antagonist that is particularly useful in treating the nausea and vomiting associated with anesthesia, mildly emetic cancer chemotherapy agents, radiation therapy, and toxins. this piperazine phenothiazine does not prevent vertigo or motion sickness. (from ama drug evaluations annual, 1994, p457)
  • Thioridazine

    a phenothiazine antipsychotic used in the management of phycoses, including schizophrenia.
  • Trifluoperazine

    a phenothiazine with actions similar to chlorpromazine. it is used as an antipsychotic and an antiemetic.
  • Triflupromazine

    a phenothiazine used as an antipsychotic agent and as an antiemetic.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AcepromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
AcetophenazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
AlimemazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ButaperazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
CarfenazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
CarphenazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ChlorpromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
CompazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
CyamemazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
DimetotiazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
DioxopromethazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
DixyrazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
FentazinT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
FluopromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
FluphenazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
IsopromethazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
LargactilT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
LevomepromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
LevopromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MellarilT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MepazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MequitazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MesoridazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MethdilazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MethopromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MethotrimeprazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MethoxypromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
MetofenazateT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
OxomemazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PecazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PerazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PericiazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PerphenazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
Phenothiazine (psychotropic) NECT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
Phenothiazine (psychotropic) NEC::insecticideT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PiperacetazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PipotiazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PlegicilT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ProchlorperazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
PromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
Promethazine (teoclate)T43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
Propylaminopheno-thiazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
SparineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
StelazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
StemetilT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
SulforidazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
Thiazinamium metilsulfateT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ThiethylperazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ThiopropazateT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ThioproperazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ThioridazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
ThorazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
TindalT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
TrifluoperazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6
TriflupromazineT43.3X1T43.3X2T43.3X3T43.3X4T43.3X5T43.3X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T43.3X3A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
969.1 Pois-phenothiazine tranq
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E962.0 Assault-pois w medic agt
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T43.3X3AOverview

Is T43.3X3A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T43.3X3A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by phenothiazine antipsychotics and neuroleptics, assault, such as an emergency visit or first evaluation.

What MS-DRG does T43.3X3A group to?

When poisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T43.3X3A?

Under the General Equivalence Mappings, poisoning by phenothiazine antipsychotics and neuroleptics, assault, initial encounter converts to ICD-9-CM 969.1 (pois-phenothiazine tranq) and E962.0 (assault-pois w medic agt). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.