2026 ICD-10-CM Diagnosis Code T43.223SPoisoning by selective serotonin reuptake inhibitors, assault, sequela
T43.223S is a billable ICD-10-CM diagnosis code for poisoning by selective serotonin reuptake inhibitors, assault, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.
Code Identity
Code Classification
Present on Admission (POA)Billing
T43.223S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Coding GuidelinesGuidance
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (T43). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Citalopram
a furancarbonitrile that is one of the selective serotonin reuptake inhibitors used as an antidepressant. the drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate dyskinesia.Fluoxetine
the first highly specific serotonin uptake inhibitor. it is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.Fluvoxamine
a selective serotonin reuptake inhibitor that is used in the treatment of depression and a variety of anxiety disorders.Zimeldine
one of the selective serotonin reuptake inhibitors formerly used for depression but was withdrawn worldwide in september 1983 because of the risk of guillain-barre syndrome associated with its use. (from martindale, the extra pharmacopoeia, 29th ed, p385)
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
| Substance | Accidental | Self-harm | Assault | Undetermined | Adverse Effect | Underdosing |
|---|---|---|---|---|---|---|
| Citalopram | T43.221 | T43.222 | T43.223 | T43.224 | T43.225 | T43.226 |
| Femoxetine | T43.221 | T43.222 | T43.223 | T43.224 | T43.225 | T43.226 |
| Fluoxetine | T43.221 | T43.222 | T43.223 | T43.224 | T43.225 | T43.226 |
| Fluvoxamine | T43.221 | T43.222 | T43.223 | T43.224 | T43.225 | T43.226 |
| Indalpine | T43.221 | T43.222 | T43.223 | T43.224 | T43.225 | T43.226 |
| Zimeldine | T43.221 | T43.222 | T43.223 | T43.224 | T43.225 | T43.226 |
Patient EducationClinical
Antidepressants
Antidepressants are prescription medicines to treat depression. Depression is more than feeling a little sad or "blue" for a few days. It's a very common, serious medical illness that affects your mood and general mental health It can make you feel tired, hopeless, worried, or fearful. It can change your thinking, sleeping, and eating.
The full article covers:
- What are antidepressants?
- Are antidepressants used for other conditions?
- What are the different types of antidepressants?
- Which type of antidepressant is right for me?
- How long do antidepressants take to work?
- How long will I need to take an antidepressant?
- What are the side effects of antidepressants?
- What can I do to take antidepressants safely?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T43.223S to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T43.223SOverview
Is T43.223S a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by selective serotonin reuptake inhibitors, assault, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character S in T43.223S mean?
The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by selective serotonin reuptake inhibitors, assault itself has resolved, not the original event.
What MS-DRG does T43.223S group to?
When poisoning by selective serotonin reuptake inhibitors, assault, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.
Is T43.223S exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by selective serotonin reuptake inhibitors, assault, sequela on inpatient claims.
What is the ICD-9 equivalent of T43.223S?
Under the General Equivalence Mappings, poisoning by selective serotonin reuptake inhibitors, assault, sequela converts to ICD-9-CM 909.0 (late eff drug poisoning) and E969 (late effect assault). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
