2026 ICD-10-CM Diagnosis Code T43.214APoisoning by selective serotonin and norepinephrine reuptake inhibitors, undetermined, initial encounter
T43.214A is a billable ICD-10-CM diagnosis code for poisoning by selective serotonin and norepinephrine reuptake inhibitors, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.
Code Identity
Code Classification
Coding GuidelinesGuidance
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (T43). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Trazodone
a serotonin uptake inhibitor that is used as an antidepressive agent. it has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. it is generally more useful in depressive disorders associated with insomnia and anxiety. this drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (from ama drug evaluations annual, 1994, p309)
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
Patient EducationClinical
Poisoning
A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T43.214A to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T43.214AOverview
Is T43.214A a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by selective serotonin and norepinephrine reuptake inhibitors, undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character A in T43.214A mean?
The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by selective serotonin and norepinephrine reuptake inhibitors, undetermined, such as an emergency visit or first evaluation.
What MS-DRG does T43.214A group to?
When poisoning by selective serotonin and norepinephrine reuptake inhibitors, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of T43.214A?
Under the General Equivalence Mappings, poisoning by selective serotonin and norepinephrine reuptake inhibitors, undetermined, initial encounter converts to ICD-9-CM 969.02 (pois serotn/norepinephrn) and E980.3 (undeterm pois-psychotrop). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
