2027 ICD-10-CM Diagnosis Code T42.4X3SPoisoning by benzodiazepines, assault, sequela

ICD-10-CM Codes›S00–T88›T36-T50›T42

ICD-10-CM T42.4X3S
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T42.4X3S is a billable ICD-10-CM diagnosis code for poisoning by benzodiazepines, assault, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T42.4X3S
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by benzodiazepines, assault, sequela
Short Description
Poisoning by benzodiazepines, assault, sequela
Same as the full description in the CMS dataset.
Parent Code
Poisoning by benzodiazepines, assault

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT42Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
This CodeT42.4X3SPoisoning by benzodiazepines, assault, sequela

Present on Admission (POA)Billing

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (T42). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T42.4X3S: its own notes plus those printed at T42, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From T42 Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs applies to 162 codes
  • drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.--F19.-)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T42 Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs applies to 162 codes
  • The appropriate 7th character is to be added to each code from category T42
  • Ainitial encounter
  • Dsubsequent encounter
  • Ssequela this code

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T42.4X3S, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming T42.4X3S: they are not reported together with it, unless the two conditions are unrelated.

  • T41 Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases
    benzodiazepines (T42.4-) names T42.4-, which includes this code

Excludes2 2

These codes carry an Excludes2 note naming T42.4X3S: its condition is not part of those codes, and both may be reported when the patient has both.

  • F13.2 Sedative, hypnotic or anxiolytic-related dependence
    sedative, hypnotic, or anxiolytic poisoning (T42.-) names T42.-, which includes this code
  • T43 Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
    benzodiazepines (T42.4-) names T42.4-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AlprazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
BentazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
BenzodiapinT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
Benzodiazepine NECT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
BromazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
BrotizolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
CamazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
CarpipramineT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
Central nervous system::depressants::benzodiazepinesT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
ChlordiazepoxideT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
ClobazamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
ClonazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
Clorazepate (dipotassium)T42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
ClotiazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
CloxazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
ClozapineT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
DalmaneT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
DelorazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
DiazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
EstazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
Ethyl::loflazepateT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
EtizolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
FludiazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
FlunitrazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
FlurazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
FlutazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
FlutoprazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
HalazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
HaloxazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
KetazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
LibriumT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
LoprazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
LorazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
LormetazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
MedazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
MexazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
MidazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
NimetazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
NitrazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
NordazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
OxazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
OxazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
PerlapineT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
PinazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
PrazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
QuazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
RohypnolT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
SeraxT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
TemazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
TetrazepamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
TofisopamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
Tranquilizer NEC::benzodiazepine NECT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
TranxeneT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
TriazolamT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6
ValiumT42.4X1T42.4X2T42.4X3T42.4X4T42.4X5T42.4X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T42.4X3S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.0 Late eff drug poisoning
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E969 Late effect assault
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T42.4X3SOverview

What is the ICD-10 code for poisoning by benzodiazepines, assault, sequela?

The ICD-10-CM code for poisoning by benzodiazepines, assault, sequela is T42.4X3S (sometimes written as T424X3S). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is T42.4X3S (Poisoning by benzodiazepines, assault) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by benzodiazepines, assault, sequela on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character S in T42.4X3S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by benzodiazepines, assault itself has resolved, not the original event.

What MS-DRG does T42.4X3S group to?

When poisoning by benzodiazepines, assault, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 923, 922, with relative weights from 0.9980 to 1.6248 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T42.4X3S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by benzodiazepines, assault, sequela on inpatient claims. The code appears in the Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances (T36-T50) range of the CMS exempt list.