2026 ICD-10-CM Diagnosis Code T42.4X2SPoisoning by benzodiazepines, intentional self-harm, sequela

AHRQ’s CCSR groups this code into broader clinical categories.

• Alprazolam

  a triazolobenzodiazepine compound with antianxiety and sedative-hypnotic actions, that is efficacious in the treatment of panic disorders, with or without agoraphobia, and in generalized anxiety disorders. (from ama drug evaluations annual, 1994, p238)

• Bromazepam

  one of the benzodiazepines that is used in the treatment of anxiety disorders.

• Chlordiazepoxide

  an anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. it has also been used in the symptomatic treatment of alcohol withdrawal.

• Clobazam

  a benzodiazepine derivative that is a long-acting gaba-a receptor agonist. it is used as an antiepileptic in the treatment of seizures, including seizures associated with lennox-gastaut syndrome. it is also used as an anxiolytic, for the short-term treatment of acute anxiety.

• Clonazepam

  an anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. it is seldom effective in generalized tonic-clonic or partial seizures. the mechanism of action appears to involve the enhancement of gamma-aminobutyric acid receptor responses.

• Clozapine

  a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. it binds several types of central nervous system receptors, and displays a unique pharmacological profile. clozapine is a serotonin antagonist, with strong binding to 5-ht 2a/2c receptor subtype. it also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine d2 receptor, a receptor commonly thought to modulate neuroleptic activity. agranulocytosis is a major adverse effect associated with administration of this agent.

• Diazepam

  a benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. its actions are mediated by enhancement of gamma-aminobutyric acid activity.

• Diazepam Binding Inhibitor

  an 86-amino acid polypeptide, found in central and peripheral tissues, that displaces diazepam from the benzodiazepine recognition site on the gamma-aminobutyric acid receptor (receptors, gaba). it also binds medium- and long-chain acyl-coa esters and serves as an acyl-coa transporter. this peptide regulates lipid metabolism.

• Receptors, GABA-A

  cell surface proteins which bind gamma-aminobutyric acid and contain an integral membrane chloride channel. each receptor is assembled as a pentamer from a pool of at least 19 different possible subunits. the receptors belong to a superfamily that share a common cysteine loop.

• Estazolam

  a benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. it has been shown in some cases to be more potent than diazepam or nitrazepam.

• Flunitrazepam

  a benzodiazepine with pharmacologic actions similar to those of diazepam that can cause anterograde amnesia. some reports indicate that it is used as a date rape drug and suggest that it may precipitate violent behavior. the united states government has banned the importation of this drug.

• Flurazepam

  a benzodiazepine derivative used mainly as a hypnotic.

• Lorazepam

  a benzodiazepine used as an anti-anxiety agent with few side effects. it also has hypnotic, anticonvulsant, and considerable sedative properties and has been proposed as a preanesthetic agent.

• Medazepam

  a benzodiazepine derivative used in the treatment of anxiety. it has sedative, muscle relaxant, and anticonvulsant properties. one of its metabolites is diazepam and one of its excretion products is oxazepam.

• Midazolam

  a short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. it is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. the short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. it is water-soluble at ph less than 4 and lipid-soluble at physiological ph.

• Nitrazepam

  a benzodiazepine derivative used as an anticonvulsant and hypnotic.

• Nordazepam

  an intermediate in the metabolism of diazepam to oxazepam. it may have actions similar to those of diazepam.

• Oxazepam

  a benzodiazepine used in the treatment of anxiety, alcohol withdrawal, and insomnia.

• Prazepam

  a benzodiazepine that is used in the treatment of anxiety disorders.

• Temazepam

  a benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent.

• Triazolam

  a short-acting benzodiazepine used in the treatment of insomnia. some countries temporarily withdrew triazolam from the market because of concerns about adverse reactions, mostly psychological, associated with higher dose ranges. its use at lower doses with appropriate care and labeling has been reaffirmed by the fda and most other countries.

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

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