2027 ICD-10-CM Diagnosis Code T42.3X6AUnderdosing of barbiturates, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T42

ICD-10-CM T42.3X6A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T42.3X6A is a billable ICD-10-CM diagnosis code for underdosing of barbiturates, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T42.3X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of barbiturates, initial encounter
Short Description
Underdosing of barbiturates, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Underdosing of barbiturates

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT42Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
This CodeT42.3X6AUnderdosing of barbiturates, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T42.3X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (T42). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T42.3X6A: its own notes plus those printed at T42.3, T42, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From T42.3 Poisoning by, adverse effect of and underdosing of barbiturates applies to 18 codes
  • poisoning by, adverse effect of and underdosing of thiobarbiturates (T41.1-)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From T42 Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs applies to 162 codes
  • drug dependence and related mental and behavioral disorders due to psychoactive substance use (F10.--F19.-)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T42 Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs applies to 162 codes
  • The appropriate 7th character is to be added to each code from category T42
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T42.3X6A, its category, or a range that includes it.

Excludes2 2

These codes carry an Excludes2 note naming T42.3X6A: its condition is not part of those codes, and both may be reported when the patient has both.

  • F13.2 Sedative, hypnotic or anxiolytic-related dependence
    sedative, hypnotic, or anxiolytic poisoning (T42.-) names T42.-, which includes this code
  • T43 Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
    barbiturates (T42.3-) names T42.3-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AgrypnalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllylisopropylmalonylureaT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllypropymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AlurateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Amobarbital (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AmylobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Amytal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Anticonvulsant::barbiturateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Anticonvulsant::combination (with barbiturate)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AprobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbenylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NECT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NEC::with tranquilizerT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BrallobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butabarbital (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButabarpalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButalbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButallylonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButethalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butisol (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CarbritalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Central nervous system::depressants::barbituratesT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CyclobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CyclobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DelvinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Dial (soap)::sedativeT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diallylbarbituric acidT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiallymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::barbituric acidT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DifebarbamateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DormiralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EnhexymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EskabarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EthobralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EtilfenT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EtovalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EunerylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EvipalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EvipanT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
FebarbamateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
FenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GardenalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GardepanylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GemonilT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HexemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexethal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HexobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
IpralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
LotusateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
LuminalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MeballymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MebaralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MebumalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MedinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MedominT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MephebarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Mephenytoin::with phenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MephobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MetharbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethituralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Methobarbital, methobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethylhexabitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethylphenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MysolineT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NealbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NembutalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeravalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeravanT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeurobarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NoptilT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NunolT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Ortal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Pentobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PernoctonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PernostonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phanodorm, phanodornT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhemitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::with::mephenytoinT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::with::phenytoinT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenonylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenylmethylbarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenytoin::with PhenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ProbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PropallylonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ProxibarbalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
QuinalbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Quinalbarbitone sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecbutabarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecbutabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SeconalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Sodium::amytalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Sodium::barbiturateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SomonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SonerylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
TalbutalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VeramonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VeronalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Vinbarbital, vinbarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Vinyl::bitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VinylbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6

Patient EducationClinical

Medication Errors

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Convert T42.3X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T42.3X6AOverview

What is the ICD-10 code for underdosing of barbiturates, initial encounter?

The ICD-10-CM code for underdosing of barbiturates, initial encounter is T42.3X6A (sometimes written as T423X6A). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is T42.3X6A (Underdosing of barbiturates) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of barbiturates, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T42.3X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of barbiturates, such as an emergency visit or first evaluation.

What MS-DRG does T42.3X6A group to?

On inpatient claims, underdosing of barbiturates, initial encounter maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can T42.3X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of barbiturates, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.