2026 ICD-10-CM Diagnosis Code T42.3X4APoisoning by barbiturates, undetermined, initial encounter

ICD-10-CM CodesS00–T88T36-T50T42

ICD-10-CM T42.3X4A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T42.3X4A is a billable ICD-10-CM diagnosis code for poisoning by barbiturates, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T42.3X4A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by barbiturates, undetermined, initial encounter
Short Description
Poisoning by barbiturates, undetermined, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Poisoning by barbiturates, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT42Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs
This CodeT42.3X4APoisoning by barbiturates, undetermined, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of antiepileptic, sedative- hypnotic and antiparkinsonism drugs (T42). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT023
External cause codes: intent of injury, undetermined
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Barbital

    a long-acting barbiturate that depresses most metabolic processes at high doses. it is used as a hypnotic and sedative and may induce dependence. barbital is also used in veterinary practice for central nervous system depression.
  • Hexobarbital

    a barbiturate that is effective as a hypnotic and sedative.
  • Mephobarbital

    a barbiturate that is metabolized to phenobarbital. it has been used for similar purposes, especially in epilepsy, but there is no evidence mephobarbital offers any advantage over phenobarbital.
  • Pentobarbital

    a short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. it is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (from ama drug evaluations annual, 1994, p236)
  • Phenobarbital

    a barbituric acid derivative that acts as a nonselective central nervous system depressant. it potentiates gamma-aminobutyric acid action on gaba-a receptors, and modulates chloride currents through receptor channels. it also inhibits glutamate induced depolarizations.
  • Secobarbital

    a barbiturate that is used as a sedative. secobarbital is reported to have no anti-anxiety activity.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AgrypnalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllylisopropylmalonylureaT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AllypropymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AlurateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Amobarbital (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AmylobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Amytal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
AprobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbenylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NECT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NEC::with tranquilizerT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Barbiturate NEC::anesthetic (intravenous)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
BrallobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butabarbital (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButabarpalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButalbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButallylonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButethalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butisol (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Butobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ButobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CarbritalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CyclobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
CyclobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DelvinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diallylbarbituric acidT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiallymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DiethylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::barbituric acidT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::carbamazineT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::carbinolT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::carbonateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::ether (vapor) [See Also: ether]T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::oxideT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::propionT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::stilbestrolT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::toluamide (nonmedicinal)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Diethyl::toluamide (nonmedicinal)::medicinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DifebarbamateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
DormiralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EnhexymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EskabarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EthobralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EtilfenT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EtovalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EunerylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EvipalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Evipal::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
EvipanT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Evipan::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
FebarbamateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
FenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GardenalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GardepanylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
GemonilT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HeptabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HexemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexethal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
HexobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexobarbital::rectalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Hexobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
IpralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
LotusateT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
LuminalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MeballymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MebaralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MebumalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MedinalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MedominT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MephebarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MephobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MetharbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethituralT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Methobarbital, methobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethylhexabitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MethylphenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
MysolineT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NealbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NembutalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeravalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeravanT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NeurobarbT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NoptilT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
NunolT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Ortal (sodium)T42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Pentobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PentymalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PernoctonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PernostonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phanodorm, phanodornT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhemitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenemalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::withT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::with::mephenytoinT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::with::phenytoinT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Phenobarbital::sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenobarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenonylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PhenylmethylbarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ProbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
PropallylonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
ProxibarbalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
QuinalbarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Quinalbarbitone sodiumT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecbutabarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecbutabarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SecobarbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SeconalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SomonalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
SonerylT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
TalbutalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VeramonT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VeronalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
Vinbarbital, vinbarbitoneT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6
VinylbitalT42.3X1T42.3X2T42.3X3T42.3X4T42.3X5T42.3X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T42.3X4A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
967.0 Poisoning-barbiturates
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E980.1 Undeterm pois-barbiturat
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T42.3X4AOverview

Is T42.3X4A (Poisoning by barbiturates, undetermined) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by barbiturates, undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T42.3X4A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by barbiturates, undetermined, such as an emergency visit or first evaluation.

What MS-DRG does T42.3X4A group to?

When poisoning by barbiturates, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T42.3X4A?

Under the General Equivalence Mappings, poisoning by barbiturates, undetermined, initial encounter converts to ICD-9-CM 967.0 (poisoning-barbiturates) and E980.1 (undeterm pois-barbiturat). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.