2027 ICD-10-CM Diagnosis Code T41.1X2APoisoning by intravenous anesthetics, intentional self-harm, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T41

ICD-10-CM T41.1X2A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T41.1X2A is a billable ICD-10-CM diagnosis code for poisoning by intravenous anesthetics, intentional self-harm, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, self-harm; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

For Medicare Advantage risk adjustment, T41.1X2A maps to CMS-HCC Category 155 (Major Depression, Moderate or Severe, without Psychosis) under the V28 model, adding a risk factor of about 0.299 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
T41.1X2A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by intravenous anesthetics, intentional self-harm, initial encounter
Short Description
Poisoning by intravenous anesthetics, self-harm, init
Parent Code
Poisoning by intravenous anesthetics, intentional self-harm

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT41Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases
This CodeT41.1X2APoisoning by intravenous anesthetics, intentional self-harm, initial encounter

Medicare Risk Adjustment (HCC)Billing

T41.1X2A maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 155— Major Depression, Moderate or Severe, without Psychosis
Payment HCC · PY 2027 one of 371 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.299
community, non-dual, aged · ranges 0.108–0.316 across segments
Hierarchy
Superseded by HCC 151, HCC 152, HCC 153, and HCC 154
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 59
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 58 · ESRD (V21): HCC 58 · ESRD (V24): HCC 59
ESRD V21 weights: 0.091 dialysis, 0.217–0.260 functioning graft · ESRD V24 weights: 0.066 dialysis, 0.129–0.259 functioning graft
Part D (RxHCC)
RxHCC 132 — Depression
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Etomidate overdose
  • Etomidate poisoning
  • Intentional barbiturate overdose
  • Intentional etomidate overdose
  • Intentional etomidate poisoning
  • Intentional methohexitone overdose
  • Intentional methohexitone poisoning
  • Intentional thiopental overdose
  • Intentional thiopental poisoning
  • Methohexitone overdose
  • Poisoning by methohexital
  • Poisoning caused by thiopental
  • Thiopental overdose

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases (T41). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T41.1X2A: its own notes plus those printed at T41, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From T41 Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases applies to 126 codes
  • benzodiazepines (T42.4-)
  • cocaine (T40.5-)
  • complications of anesthesia during pregnancy (O29.-)
  • complications of anesthesia during labor and delivery (O74.-)
  • complications of anesthesia during the puerperium (O89.-)
  • opioids (T40.0-T40.2-)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T41 Poisoning by, adverse effect of and underdosing of anesthetics and therapeutic gases applies to 126 codes
  • The appropriate 7th character is to be added to each code from category T41
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T41.1X2A, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming T41.1X2A: they are not reported together with it, unless the two conditions are unrelated.

  • T42.3 Poisoning by, adverse effect of and underdosing of barbiturates
    poisoning by, adverse effect of and underdosing of thiobarbiturates (T41.1-) names T41.1-, which includes this code

Use Additional Code 4

These codes say to use an additional code from the note, and T41.1X2A is one of the codes named.

  • J95.4 Chemical pneumonitis due to anesthesia
    code for adverse effect, if applicable, to identify drug (T41.- with fifth or sixth character 5) names T41.-, which includes this code
  • T88.2 Shock due to anesthesia
    code for adverse effect, if applicable, to identify drug (T41.- with fifth or sixth character 5) names T41.-, which includes this code
  • T88.3 Malignant hyperthermia due to anesthesia
    code for adverse effect, if applicable, to identify drug (T41.- with fifth or sixth character 5) names T41.-, which includes this code
  • T88.5 Other complications of anesthesia
    code for adverse effect, if applicable, to identify drug (T41.- with fifth or sixth character 5) names T41.-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT021
External cause codes: intent of injury, self-harm
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD012
Suicidal ideation/attempt/intentional self-harm
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Etomidate

    imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. it has been proposed as an induction anesthetic.
  • Methohexital

    an intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
  • Thiamylal

    a barbiturate that is administered intravenously for the production of complete anesthesia of short duration, for the induction of general anesthesia, or for inducing a hypnotic state. (from martindale, the extra pharmacopoeia, 30th ed, p919)
  • Thiopental

    a barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AlfadoloneT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
AlfaxaloneT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
AlphadoloneT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
AlphaxaloneT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Anesthetic NEC [See Also: Anesthesia]::intravenous NECT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Anesthetic NEC [See Also: Anesthesia]::thiobarbiturateT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Barbiturate NEC::anesthetic (intravenous)T41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Brevital (sodium)T41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Buthalitone (sodium)T41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Butyl::thiobarbital sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Central nervous system::depressants::anesthetic (general) NEC::intravenousT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
EtomidateT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Evipal::sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Evipan::sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Hexobarbital::sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
IntranarconT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
KemithalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
MethohexitalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
MethohexitoneT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
PentothalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
SernylT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Sodium::thiopentalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
SuritalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
ThialbarbitalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
ThiamylalT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Thiamylal::sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Thiobarbital sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Thiobarbiturate anestheticT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Thiobutabarbital sodiumT41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Thiopental (sodium)T41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6
Thiopentone (sodium)T41.1X1T41.1X2T41.1X3T41.1X4T41.1X5T41.1X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T41.1X2A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
968.3 Poison-intraven anesthet
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E950.0 Poison-analgesics
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T41.1X2AOverview

Is T41.1X2A (Poisoning by intravenous anesthetics, intentional self-harm) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by intravenous anesthetics, intentional self-harm, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T41.1X2A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by intravenous anesthetics, intentional self-harm, such as an emergency visit or first evaluation.

What MS-DRG does T41.1X2A group to?

When poisoning by intravenous anesthetics, intentional self-harm, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 918, 917, with relative weights from 0.8716 to 1.5698 depending on complications. Higher weights mean higher Medicare reimbursement.

Can T41.1X2A be reported with a code from T42.4?

Not as a rule. The Excludes1 note at T41, which applies to T41.1X2A, lists "benzodiazepines (T42.4-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of T41.1X2A?

Under the General Equivalence Mappings, poisoning by intravenous anesthetics, intentional self-harm, initial encounter converts to ICD-9-CM 968.3 (poison-intraven anesthet) and E950.0 (poison-analgesics). The mapping is approximate, so confirm the match fits the documentation.

What HCC is T41.1X2A?

T41.1X2A (poisoning by intravenous anesthetics, intentional self-harm, initial encounter) maps to CMS-HCC Category 155 (Major Depression, Moderate or Severe, without Psychosis), commonly written as HCC 155, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 59 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 132.

Does T41.1X2A risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, T41.1X2A adds a risk adjustment factor of about 0.299 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.108 to 0.316 depending on the payment segment). A more severe related category (HCC 151, HCC 152, HCC 153, and HCC 154) supersedes it when both are reported. See the full factor table on the HCC 155 category page.