2027 ICD-10-CM Diagnosis Code T37.3X4APoisoning by other antiprotozoal drugs, undetermined, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T37

ICD-10-CM T37.3X4A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T37.3X4A is a billable ICD-10-CM diagnosis code for poisoning by other antiprotozoal drugs, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T37.3X4A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by other antiprotozoal drugs, undetermined, initial encounter
Short Description
Poisoning by oth antiprotozoal drugs, undetermined, init
Parent Code
Poisoning by other antiprotozoal drugs, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT37Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics
This CodeT37.3X4APoisoning by other antiprotozoal drugs, undetermined, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (T37). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T37.3X4A: its own notes plus those printed at T37, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From T37 Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics applies to 144 codes
  • anti-infectives topically used for ear, nose and throat (T49.6-)
  • anti-infectives topically used for eye (T49.5-)
  • locally applied anti-infectives NEC (T49.0-)
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T37 Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics applies to 144 codes
  • The appropriate 7th character is to be added to each code from category T37
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT023
External cause codes: intent of injury, undetermined
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AcetarsolT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
ActerolT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
AminitrozoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Anti-infective NEC::antiprotozoal NECT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Antimony (compounds) (vapor) NEC::dimercaptosuccinateT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Antimony (compounds) (vapor) NEC::sodium dimercaptosuccinateT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Antiprotozoal drug NECT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Antitrichomonal drugT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
ArsthinolT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
AzanidazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
BenznidazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
BialamicolT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
CarbarsoneT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
ClefamideT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
DehydroemetineT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
DHET37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
DifetarsoneT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
DiloxanideT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
EmetineT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
EtofamideT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
FlagylT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
GlaucarubinT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
GlycobiarsolT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
HydroxystilbamidineT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Melarsonyl potassiumT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
MelarsoprolT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
MisonidazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
NifurtimoxT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
NimorazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
NitrimidazineT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
OrnidazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
OxophenarsineT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
PentamidineT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
PhanquinoneT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
PhanquoneT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
SecnidazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Sodium::antimony gluconateT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Sodium::stibogluconateT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
StibogluconateT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Stilbamidine (isetionate)T37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
TeclozanT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
TenonitrozoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
TinidazoleT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
Trichomonacides NECT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6
TryparsamideT37.3X1T37.3X2T37.3X3T37.3X4T37.3X5T37.3X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T37.3X4A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
961.5 Pois-antiprotoz drug NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E980.4 Undet pois-med agnt NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T37.3X4AOverview

Is T37.3X4A (Poisoning by other antiprotozoal drugs, undetermined) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by other antiprotozoal drugs, undetermined, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T37.3X4A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by other antiprotozoal drugs, undetermined, such as an emergency visit or first evaluation.

What MS-DRG does T37.3X4A group to?

When poisoning by other antiprotozoal drugs, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 918, 917, with relative weights from 0.8716 to 1.5698 depending on complications. Higher weights mean higher Medicare reimbursement.

Can T37.3X4A be reported with a code from T49.6?

Not as a rule. The Excludes1 note at T37, which applies to T37.3X4A, lists "anti-infectives topically used for ear, nose and throat (T49.6-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of T37.3X4A?

Under the General Equivalence Mappings, poisoning by other antiprotozoal drugs, undetermined, initial encounter converts to ICD-9-CM 961.5 (pois-antiprotoz drug NEC) and E980.4 (undet pois-med agnt NEC). The mapping is approximate, so confirm the match fits the documentation.