2026 ICD-10-CM Diagnosis Code T37.2X1SPoisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela

ICD-10-CM CodesS00–T88T36-T50T37

ICD-10-CM T37.2X1S
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T37.2X1S is a billable ICD-10-CM diagnosis code for poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T37.2X1S
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela
Short Description
Poisn by antimalari/drugs acting on bld protzoa, acc, sqla
Parent Code
Poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional)

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT37Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics
This CodeT37.2X1SPoisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela

Present on Admission (POA)Billing

T37.2X1S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Accidental chloroquine overdose
  • Accidental chloroquine poisoning
  • Accidental cycloguanil poisoning
  • Accidental mefloquine overdose
  • Accidental mefloquine poisoning
  • Accidental primaquine overdose
  • Accidental primaquine poisoning
  • Accidental proguanil overdose
  • Accidental proguanil poisoning
  • Accidental pyrimethamine overdose
  • Accidental pyrimethamine poisoning
  • Accidental quinine overdose
  • Accidental quinine poisoning
  • Antimalarial drug overdose
  • Biguanide overdose
  • Chloroquine overdose
  • Mefloquine overdose
  • Mefloquine poisoning
  • Poisoning by chloroquine
  • Poisoning by cycloguanil
  • Poisoning by primaquine
  • Poisoning by proguanil
  • Poisoning by pyrimethamine
  • Poisoning by quinine
  • Primaquine overdose
  • Proguanil overdose
  • Pyrimethamine overdose
  • Quinine overdose

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (T37). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Amodiaquine

    a 4-aminoquinoline compound with anti-inflammatory properties.
  • Chloroquine

    the prototypical antimalarial agent with a mechanism that is not well understood. it has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.
  • Cinchona

    a genus of rubiaceous south american trees that yields the toxic cinchona alkaloids from their bark; quinine; quinidine; chinconine, cinchonidine and others are used to treat malaria and cardiac arrhythmias.
  • Cinchona Alkaloids

    alkaloids extracted from various species of cinchona.
  • Eflornithine

    an inhibitor of ornithine decarboxylase, the rate limiting enzyme of the polyamine biosynthetic pathway.
  • Mefloquine

    a phospholipid-interacting antimalarial drug (antimalarials). it is very effective against plasmodium falciparum with very few side effects.
  • Primaquine

    an aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. it has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. adverse effects include anemias and gi disturbances. (from martindale, the extra pharmacopeia, 30th ed, p404)
  • Proguanil

    a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.
  • Pyrimethamine

    one of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
  • Quinacrine

    an acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. it has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. it is used in cell biological experiments as an inhibitor of phospholipase a2.
  • Quinacrine Mustard

    nitrogen mustard analog of quinacrine used primarily as a stain in the studies of chromosomes and chromatin. fluoresces by reaction with nucleic acids in chromosomes.
  • Quinine

    an alkaloid derived from the bark of the cinchona tree. it is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. it was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. the mechanisms of its antimalarial effects are not well understood.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
8-Aminoquinoline drugsT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
AmodiaquineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Amopyroquin (e)T37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
AntimalarialT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Antimalarial::prophylactic NECT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Antimalarial::pyrimidine derivativeT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
AralenT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
CamoquinT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
ChloroguanideT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
ChloroquineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
ChlorproguanilT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
CinchonaT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Cinchonine alkaloidsT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Cycloguanil embonateT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
DaraprimT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
EflornithineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
GuanatolT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
HalofantrineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
IsopentaquineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
MefloquineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
MepacrineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
PaludrineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Pamaquine (naphthoute)T37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
PentaquineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
PrimaquineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
ProguanilT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
PyrimethamineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Pyrimethamine::with sulfadoxineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
QuinacrineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
QuinineT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
QuinocideT37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6
Schizontozide (blood) (tissue)T37.2X1T37.2X2T37.2X3T37.2X4T37.2X5T37.2X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T37.2X1S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.0 Late eff drug poisoning
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E929.2 Late eff acc poisoning
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T37.2X1SOverview

Is T37.2X1S a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T37.2X1S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional) itself has resolved, not the original event.

What MS-DRG does T37.2X1S group to?

When poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T37.2X1S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela on inpatient claims.

What is the ICD-9 equivalent of T37.2X1S?

Under the General Equivalence Mappings, poisoning by antimalarials and drugs acting on other blood protozoa, accidental (unintentional), sequela converts to ICD-9-CM 909.0 (late eff drug poisoning) and E929.2 (late eff acc poisoning). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.