2027 ICD-10-CM Diagnosis Code R40.3Persistent vegetative state

ICD-10-CM Codes›R00–R99›R40-R46›R40

ICD-10-CM R40.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

R40.3 is a billable ICD-10-CM diagnosis code for persistent vegetative state. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 80 through 81, 791, 793. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 718 closely related codes. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. Coders also document this condition as permanent vegetative state. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coma; stupor; and brain damage.

For Medicare Advantage risk adjustment, R40.3 maps to CMS-HCC Category 202 (Coma, Brain Compression/Anoxic Damage) under the V28 model, adding a risk factor of about 0.543 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
R40.3
Billable Status
Yes — Valid for Submission
Code Describes
Persistent vegetative state
Short Description
Persistent vegetative state
Same as the full description in the CMS dataset.
Parent Code
Somnolence, stupor and coma

Code Classification

ChapterR00–R99Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
SectionR40-R46Symptoms and signs involving cognition, perception, emotional state and behavior
CategoryR40Somnolence, stupor and coma
This CodeR40.3Persistent vegetative state

Medicare Risk Adjustment (HCC)Billing

R40.3 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 202— Coma, Brain Compression/Anoxic Damage
Payment HCC · PY 2027 one of 61 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.543
community, non-dual, aged · ranges 0.097–0.721 across segments
Hierarchy
Superseded by HCC 63, HCC 397, and HCC 398
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 80
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 80 · ESRD (V21): HCC 80 · ESRD (V24): HCC 80
ESRD V21 weights: 0.043 dialysis, 0.000–0.184 functioning graft · ESRD V24 weights: 0.076 dialysis, 0.063–0.679 functioning graft
Part D (RxHCC)
Not mapped
R40.3 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Permanent vegetative state
  • Persistent vegetative state

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to R40.3: its own notes plus those printed at R40, block R40-R46, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From R40 Somnolence, stupor and coma applies to 101 codes
  • neonatal coma (P91.5)
  • somnolence, stupor and coma in diabetes (E08-E13)
  • somnolence, stupor and coma in hepatic failure (K72.-)
  • somnolence, stupor and coma in hypoglycemia (nondiabetic) (E15)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block R40-R46 Symptoms and signs involving cognition, perception, emotional state and behavior applies to 157 codes
  • symptoms and signs constituting part of a pattern of mental disorder (F01-F99)
From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)

Notes

General instructions on how these codes are used.

From Chapter 18 (R00-R99) Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified applies to 774 codes
  • This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
  • Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
  • The conditions and signs or symptoms included in categories R00-R94 consist of:
  • (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
  • (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
  • (c) provisional diagnosis in a patient who failed to return for further investigation or care;
  • (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
  • (e) cases in which a more precise diagnosis was not available for any other reason;
  • (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name R40.3, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming R40.3: they are not reported together with it, unless the two conditions are unrelated.

  • R41.82 Altered mental status, unspecified
    altered level of consciousness (R40.-) names R40.-, which includes this code

Use Additional Code 2

These codes say to use an additional code from the note, and R40.3 is one of the codes named.

  • T65.85 Toxic effect of medetomidine
    somnolence, stupor and coma (R40.-) names R40.-, which includes this code
  • T67.0 Heatstroke and sunstroke
    coma and stupor (R40.-) names R40.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS013
Coma; stupor; and brain damage
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Persistent Vegetative State

    vegetative state refers to the neurocognitive status of individuals with severe brain damage, in whom physiologic functions (sleep-wake cycles, autonomic control, and breathing) persist, but awareness (including all cognitive function and emotion) is abolished.

Patient EducationClinical

Coma

A coma is a deep state of unconsciousness. An individual in a coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert R40.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
780.03 Persistent vegtv state
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About R40.3Overview

What is the ICD-10 code for persistent vegetative state?

The ICD-10-CM code for persistent vegetative state is R40.3 (sometimes written as R403). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is R40.3 (Somnolence, stupor and coma) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report persistent vegetative state on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does R40.3 group to?

When persistent vegetative state is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 81, 80, with relative weights from 0.7941 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is R40.3 a CC or MCC?

CMS lists R40.3 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 718 closely related codes in its exclusion list.

Can R40.3 be a principal diagnosis?

Use it with care. This is a symptom code, so once a definitive diagnosis explaining the persistent vegetative state is established, that condition takes the principal position instead.

What HCC is R40.3?

R40.3 (persistent vegetative state) maps to CMS-HCC Category 202 (Coma, Brain Compression/Anoxic Damage), commonly written as HCC 202, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 80 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.

Does R40.3 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, R40.3 adds a risk adjustment factor of about 0.543 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.097 to 0.721 depending on the payment segment). A more severe related category (HCC 63, HCC 397, and HCC 398) supersedes it when both are reported. See the full factor table on the HCC 202 category page.