Somnolence, stupor and coma (R40)

    • ICD-10 Index

      • Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00–R99)

        • Symptoms and signs involving cognition, perception, emotional state and behavior (R40-R46)

            • Somnolence, stupor and coma (R40)
            • R40 - Somnolence, stupor and coma NON-BILLABLE CODE
            • R40.0 - Somnolence BILLABLE CODE
            • R40.1 - Stupor BILLABLE CODE
            • R40.2 - Coma NON-BILLABLE CODE
            • R40.20 - Unspecified coma BILLABLE CODE
            • R40.21 - Coma scale, eyes open NON-BILLABLE CODE
            • R40.211 - Coma scale, eyes open, never NON-BILLABLE CODE
            • R40.2110 - Coma scale, eyes open, never, unspecified time BILLABLE CODE
            • R40.2111 - Coma scale, eyes open, never, in the field BILLABLE CODE
            • R40.2112 - Coma scale, eyes open, never, EMR BILLABLE CODE
            • R40.2113 - Coma scale, eyes open, never, at hospital admission BILLABLE CODE
            • R40.2114 - Coma scale, eyes open, never, 24+hrs BILLABLE CODE
            • R40.212 - Coma scale, eyes open, to pain NON-BILLABLE CODE
            • R40.2120 - Coma scale, eyes open, to pain, unspecified time BILLABLE CODE
            • R40.2121 - Coma scale, eyes open, to pain, in the field BILLABLE CODE
            • R40.2122 - Coma scale, eyes open, to pain, EMR BILLABLE CODE
            • R40.2123 - Coma scale, eyes open, to pain, at hospital admission BILLABLE CODE
            • R40.2124 - Coma scale, eyes open, to pain, 24+hrs BILLABLE CODE
            • R40.213 - Coma scale, eyes open, to sound NON-BILLABLE CODE
            • R40.2130 - Coma scale, eyes open, to sound, unspecified time BILLABLE CODE
            • R40.2131 - Coma scale, eyes open, to sound, in the field BILLABLE CODE
            • R40.2132 - Coma scale, eyes open, to sound, EMR BILLABLE CODE
            • R40.2133 - Coma scale, eyes open, to sound, at hospital admission BILLABLE CODE
            • R40.2134 - Coma scale, eyes open, to sound, 24+hrs BILLABLE CODE
            • R40.214 - Coma scale, eyes open, spontaneous NON-BILLABLE CODE
            • R40.2140 - Coma scale, eyes open, spontaneous, unspecified time BILLABLE CODE
            • R40.2141 - Coma scale, eyes open, spontaneous, in the field BILLABLE CODE
            • R40.2142 - Coma scale, eyes open, spontaneous, EMR BILLABLE CODE
            • R40.2143 - Coma scale, eyes open, spontaneous, at hospital admission BILLABLE CODE
            • R40.2144 - Coma scale, eyes open, spontaneous, 24+hrs BILLABLE CODE
            • R40.22 - Coma scale, best verbal response NON-BILLABLE CODE
            • R40.221 - Coma scale, best verbal response, none NON-BILLABLE CODE
            • R40.2210 - Coma scale, best verbal response, none, unspecified time BILLABLE CODE
            • R40.2211 - Coma scale, best verbal response, none, in the field BILLABLE CODE
            • R40.2212 - Coma scale, best verbal response, none, EMR BILLABLE CODE
            • R40.2213 - Coma scale, best verbal response, none, admit BILLABLE CODE
            • R40.2214 - Coma scale, best verbal response, none, 24+hrs BILLABLE CODE
            • R40.222 - Coma scale, best verbal response, incomprehensible words NON-BILLABLE CODE
            • R40.2220 - Coma scale, best verb, incomprehensible words, unsp time BILLABLE CODE
            • R40.2221 - Coma scale, best verb, incomprehensible words, in the field BILLABLE CODE
            • R40.2222 - Coma scale, best verb, incomprehensible words, EMR BILLABLE CODE
            • R40.2223 - Coma scale, best verb, incomprehensible words, admit BILLABLE CODE
            • R40.2224 - Coma scale, best verb, incomprehensible words, 24+hrs BILLABLE CODE
            • R40.223 - Coma scale, best verbal response, inappropriate words NON-BILLABLE CODE
            • R40.2230 - Coma scale, best verb, inappropriate words, unsp time BILLABLE CODE
            • R40.2231 - Coma scale, best verb, inappropriate words, in the field BILLABLE CODE
            • R40.2232 - Coma scale, best verbal response, inappropriate words, EMR BILLABLE CODE
            • R40.2233 - Coma scale, best verbal response, inappropriate words, admit BILLABLE CODE
            • R40.2234 - Coma scale, best verb, inappropriate words, 24+hrs BILLABLE CODE
            • R40.224 - Coma scale, best verbal response, confused conversation NON-BILLABLE CODE
            • R40.2240 - Coma scale, best verb, confused conversation, unsp time BILLABLE CODE
            • R40.2241 - Coma scale, best verb, confused conversation, in the field BILLABLE CODE
            • R40.2242 - Coma scale, best verbal response, confused conversation, EMR BILLABLE CODE
            • R40.2243 - Coma scale, best verb, confused conversation, admit BILLABLE CODE
            • R40.2244 - Coma scale, best verb, confused conversation, 24+hrs BILLABLE CODE
            • R40.225 - Coma scale, best verbal response, oriented NON-BILLABLE CODE
            • R40.2250 - Coma scale, best verbal response, oriented, unspecified time BILLABLE CODE
            • R40.2251 - Coma scale, best verbal response, oriented, in the field BILLABLE CODE
            • R40.2252 - Coma scale, best verbal response, oriented, EMR BILLABLE CODE
            • R40.2253 - Coma scale, best verbal response, oriented, admit BILLABLE CODE
            • R40.2254 - Coma scale, best verbal response, oriented, 24+hrs BILLABLE CODE
            • R40.23 - Coma scale, best motor response NON-BILLABLE CODE
            • R40.231 - Coma scale, best motor response, none NON-BILLABLE CODE
            • R40.2310 - Coma scale, best motor response, none, unspecified time BILLABLE CODE
            • R40.2311 - Coma scale, best motor response, none, in the field BILLABLE CODE
            • R40.2312 - Coma scale, best motor response, none, EMR BILLABLE CODE
            • R40.2313 - Coma scale, best motor response, none, at hospital admission BILLABLE CODE
            • R40.2314 - Coma scale, best motor response, none, 24+hrs BILLABLE CODE
            • R40.232 - Coma scale, best motor response, extension NON-BILLABLE CODE
            • R40.2320 - Coma scale, best motor response, extension, unspecified time BILLABLE CODE
            • R40.2321 - Coma scale, best motor response, extension, in the field BILLABLE CODE
            • R40.2322 - Coma scale, best motor response, extension, EMR BILLABLE CODE
            • R40.2323 - Coma scale, best motor response, extension, admit BILLABLE CODE
            • R40.2324 - Coma scale, best motor response, extension, 24+hrs BILLABLE CODE
            • R40.233 - Coma scale, best motor response, abnormal flexion NON-BILLABLE CODE
            • R40.2330 - Coma scale, best motor, abnormal flexion, unspecified time BILLABLE CODE
            • R40.2331 - Coma scale, best motor, abnormal flexion, in the field BILLABLE CODE
            • R40.2332 - Coma scale, best motor response, abnormal flexion, EMR BILLABLE CODE
            • R40.2333 - Coma scale, best motor response, abnormal flexion, admit BILLABLE CODE
            • R40.2334 - Coma scale, best motor response, abnormal flexion, 24+hrs BILLABLE CODE
            • R40.234 - Coma scale, best motor response, flexion withdrawal NON-BILLABLE CODE
            • R40.2340 - Coma scale, best motor, flexion withdrawal, unsp time BILLABLE CODE
            • R40.2341 - Coma scale, best motor, flexion withdrawal, in the field BILLABLE CODE
            • R40.2342 - Coma scale, best motor response, flexion withdrawal, EMR BILLABLE CODE
            • R40.2343 - Coma scale, best motor response, flexion withdrawal, admit BILLABLE CODE
            • R40.2344 - Coma scale, best motor response, flexion withdrawal, 24+hrs BILLABLE CODE
            • R40.235 - Coma scale, best motor response, localizes pain NON-BILLABLE CODE
            • R40.2350 - Coma scale, best motor response, localizes pain, unsp time BILLABLE CODE
            • R40.2351 - Coma scale, best motor, localizes pain, in the field BILLABLE CODE
            • R40.2352 - Coma scale, best motor response, localizes pain, EMR BILLABLE CODE
            • R40.2353 - Coma scale, best motor response, localizes pain, admit BILLABLE CODE
            • R40.2354 - Coma scale, best motor response, localizes pain, 24+hrs BILLABLE CODE
            • R40.236 - Coma scale, best motor response, obeys commands NON-BILLABLE CODE
            • R40.2360 - Coma scale, best motor response, obeys commands, unsp time BILLABLE CODE
            • R40.2361 - Coma scale, best motor, obeys commands, in the field BILLABLE CODE
            • R40.2362 - Coma scale, best motor response, obeys commands, EMR BILLABLE CODE
            • R40.2363 - Coma scale, best motor response, obeys commands, admit BILLABLE CODE
            • R40.2364 - Coma scale, best motor response, obeys commands, 24+hrs BILLABLE CODE
            • R40.24 - Glasgow coma scale, total score NON-BILLABLE CODE
            • R40.241 - Glasgow coma scale score 13-15 NON-BILLABLE CODE
            • R40.2410 - Glasgow coma scale score 13-15, unspecified time BILLABLE CODE
            • R40.2411 - Glasgow coma scale score 13-15, in the field BILLABLE CODE
            • R40.2412 - Glasgow coma scale score 13-15, EMR BILLABLE CODE
            • R40.2413 - Glasgow coma scale score 13-15, at hospital admission BILLABLE CODE
            • R40.2414 - Glasgow coma scale score 13-15, 24+hrs BILLABLE CODE
            • R40.242 - Glasgow coma scale score 9-12 NON-BILLABLE CODE
            • R40.2420 - Glasgow coma scale score 9-12, unspecified time BILLABLE CODE
            • R40.2421 - Glasgow coma scale score 9-12, in the field BILLABLE CODE
            • R40.2422 - Glasgow coma scale score 9-12, EMR BILLABLE CODE
            • R40.2423 - Glasgow coma scale score 9-12, at hospital admission BILLABLE CODE
            • R40.2424 - Glasgow coma scale score 9-12, 24+hrs BILLABLE CODE
            • R40.243 - Glasgow coma scale score 3-8 NON-BILLABLE CODE
            • R40.2430 - Glasgow coma scale score 3-8, unspecified time BILLABLE CODE
            • R40.2431 - Glasgow coma scale score 3-8, in the field BILLABLE CODE
            • R40.2432 - Glasgow coma scale score 3-8, EMR BILLABLE CODE
            • R40.2433 - Glasgow coma scale score 3-8, at hospital admission BILLABLE CODE
            • R40.2434 - Glasgow coma scale score 3-8, 24+hrs BILLABLE CODE
            • R40.244 - Oth coma,w/o Glasgow coma scale score,or w/part score report NON-BILLABLE CODE
            • R40.2440 - Other coma, without Glasgow, or w/part score, unsp time BILLABLE CODE
            • R40.2441 - Other coma, without Glasgow, or w/part score, in the field BILLABLE CODE
            • R40.2442 - Other coma, without documented Glasgow, or w/part score, EMR BILLABLE CODE
            • R40.2443 - Other coma, without Glasgow, or w/part score, admit BILLABLE CODE
            • R40.2444 - Other coma, without Glasgow, or w/part score, 24+hrs BILLABLE CODE
            • R40.3 - Persistent vegetative state BILLABLE CODE
            • R40.4 - Transient alteration of awareness BILLABLE CODE

Clinical Information for Somnolence, stupor and coma (R40)

Glasgow Coma Scale - A scale that assesses the response to stimuli in patients with craniocerebral injuries. The parameters are eye opening, motor response, and verbal response.

Hepatic Encephalopathy - A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Hyperglycemic Hyperosmolar Nonketotic Coma - A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed consciousness leading to COMA in the absence of KETOSIS and ACIDOSIS.

Insulin Coma - Severe HYPOGLYCEMIA induced by a large dose of exogenous INSULIN resulting in a COMA or profound state of unconsciousness from which the individual cannot be aroused.

Santalaceae - A plant family of the order Santalales, subclass Rosidae, class Magnoliopsida. They are parasites that form connections (haustoria) to their hosts to obtain water and nutrients. The one-seeded fruit may be surrounded by a brightly colored nut-like structure.

Hepatic Encephalopathy - A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Stupor - A state of reduced sensibility and response to stimuli which is distinguished from COMA in that the person can be aroused by vigorous and repeated stimulation. The person is still conscious and can make voluntary movements. It can be induced by CENTRAL NERVOUS SYSTEM AGENTS. The word derives from Latin stupere and is related to stunned, stupid, dazed or LETHARGY.

Persistent Vegetative State - Vegetative state refers to the neurocognitive status of individuals with severe brain damage, in whom physiologic functions (sleep-wake cycles, autonomic control, and breathing) persist, but awareness (including all cognitive function and emotion) is abolished.

Santalaceae - A plant family of the order Santalales, subclass Rosidae, class Magnoliopsida. They are parasites that form connections (haustoria) to their hosts to obtain water and nutrients. The one-seeded fruit may be surrounded by a brightly colored nut-like structure.

Comamonas testosteroni - A species of gram-negative, aerobic rods formerly called Pseudomonas testosteroni. It is differentiated from other Comamonas species by its ability to assimilate testosterone and to utilize phenylacetate or maleate as carbon sources.

Convulsive Therapy - Convulsions induced in order to treat MENTAL DISORDERS. It is used primarily in the treatment of severe affective disorders and SCHIZOPHRENIA.

Delftia acidovorans - A species of gram-negative rod-shaped bacteria found ubiquitously and formerly called Comamonas acidovorans and Pseudomonas acidovorans. It is the type species of the genus DELFTIA.

Diabetic Coma - A state of unconsciousness as a complication of diabetes mellitus. It occurs in cases of extreme HYPERGLYCEMIA or extreme HYPOGLYCEMIA as a complication of INSULIN therapy.

Glasgow Coma Scale - A scale that assesses the response to stimuli in patients with craniocerebral injuries. The parameters are eye opening, motor response, and verbal response.

Hepatic Encephalopathy - A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Hyperglycemic Hyperosmolar Nonketotic Coma - A serious complication of TYPE 2 DIABETES MELLITUS. It is characterized by extreme HYPERGLYCEMIA; DEHYDRATION; serum hyperosmolarity; and depressed consciousness leading to COMA in the absence of KETOSIS and ACIDOSIS.

Insulin Coma - Severe HYPOGLYCEMIA induced by a large dose of exogenous INSULIN resulting in a COMA or profound state of unconsciousness from which the individual cannot be aroused.

Akinetic Mutism - A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)

Brain Death - A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)

Coma - A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Coma, Post-Head Injury - Prolonged unconsciousness from which the individual cannot be aroused, associated with traumatic injuries to the BRAIN. This may be defined as unconsciousness persisting for 6 hours or longer. Coma results from injury to both cerebral hemispheres or the RETICULAR FORMATION of the BRAIN STEM. Contributing mechanisms include DIFFUSE AXONAL INJURY and BRAIN EDEMA. (From J Neurotrauma 1997 Oct;14(10):699-713)

Comamonadaceae - A family of gram-negative aerobic bacteria in the order BURKHOLDERIALES, encompassing the acidovorans rRNA complex. Some species are pathogenic to PLANTS.

Comamonas - A genus of gram-negative, straight or slightly curved rods which are motile by polar flagella and which accumulate poly-beta-hydroxybutyrate within the cells.

Akinetic Mutism - A syndrome characterized by a silent and inert state without voluntary motor activity despite preserved sensorimotor pathways and vigilance. Bilateral FRONTAL LOBE dysfunction involving the anterior cingulate gyrus and related brain injuries are associated with this condition. This may result in impaired abilities to communicate and initiate motor activities. (From Adams et al., Principles of Neurology, 6th ed, p348; Fortschr Neurol Psychiatr 1995 Feb;63(2):59-67)

Brain Death - A state of prolonged irreversible cessation of all brain activity, including lower brain stem function with the complete absence of voluntary movements, responses to stimuli, brain stem reflexes, and spontaneous respirations. Reversible conditions which mimic this clinical state (e.g., sedative overdose, hypothermia, etc.) are excluded prior to making the determination of brain death. (From Adams et al., Principles of Neurology, 6th ed, pp348-9)

Coma - A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.

Coma, Post-Head Injury - Prolonged unconsciousness from which the individual cannot be aroused, associated with traumatic injuries to the BRAIN. This may be defined as unconsciousness persisting for 6 hours or longer. Coma results from injury to both cerebral hemispheres or the RETICULAR FORMATION of the BRAIN STEM. Contributing mechanisms include DIFFUSE AXONAL INJURY and BRAIN EDEMA. (From J Neurotrauma 1997 Oct;14(10):699-713)

Comamonadaceae - A family of gram-negative aerobic bacteria in the order BURKHOLDERIALES, encompassing the acidovorans rRNA complex. Some species are pathogenic to PLANTS.

Comamonas - A genus of gram-negative, straight or slightly curved rods which are motile by polar flagella and which accumulate poly-beta-hydroxybutyrate within the cells.

Comamonas testosteroni - A species of gram-negative, aerobic rods formerly called Pseudomonas testosteroni. It is differentiated from other Comamonas species by its ability to assimilate testosterone and to utilize phenylacetate or maleate as carbon sources.

Convulsive Therapy - Convulsions induced in order to treat MENTAL DISORDERS. It is used primarily in the treatment of severe affective disorders and SCHIZOPHRENIA.

Delftia acidovorans - A species of gram-negative rod-shaped bacteria found ubiquitously and formerly called Comamonas acidovorans and Pseudomonas acidovorans. It is the type species of the genus DELFTIA.

Diabetic Coma - A state of unconsciousness as a complication of diabetes mellitus. It occurs in cases of extreme HYPERGLYCEMIA or extreme HYPOGLYCEMIA as a complication of INSULIN therapy.

Frontal Lobe - The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.

Reticular Formation - A region extending from the PONS & MEDULLA OBLONGATA through the MESENCEPHALON, characterized by a diversity of neurons of various sizes and shapes, arranged in different aggregations and enmeshed in a complicated fiber network.

Delftia - A genus of gram-negative, strictly aerobic chemoorganotrophic bacteria, in the family COMAMONADACEAE.

Frontal Lobe - The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.

Reticular Formation - A region extending from the PONS & MEDULLA OBLONGATA through the MESENCEPHALON, characterized by a diversity of neurons of various sizes and shapes, arranged in different aggregations and enmeshed in a complicated fiber network.

Delftia - A genus of gram-negative, strictly aerobic chemoorganotrophic bacteria, in the family COMAMONADACEAE.

Instructional Notations

Type 1 Excludes Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

  • neonatal coma P91.5
  • somnolence, stupor and coma in diabetes E08 E13
  • somnolence, stupor and coma in hepatic failure K72
  • somnolence, stupor and coma in hypoglycemia nondiabetic E15