MS-DRG 81 – Nontraumatic Stupor and Coma without MCC
A Medical DRG in MDC 01 (Diseases & Disorders of the Nervous System). Inpatient cases group to DRG 81 when the ICD-10-CM principal diagnosis is one of the 44 codes listed below and no secondary diagnosis on the MCC list is present. Its FY 2026 relative weight is 0.8956 with a geometric mean length of stay of 2.8 days.
Severity family
The grouper first assigns the case to MDC 01 from the principal diagnosis and finds no qualifying operating-room procedure (this is a Medical DRG; ICD-10-PCS codes do not drive assignment here), then applies the severity split from secondary diagnoses: with MCC → 80; without MCC → 81.
Principal Diagnosis Codes 44 codes · 3 categories
E03 Other hypothyroidism1 code
- E03.5 Myxedema coma
R40 Somnolence, stupor and coma40 codes
- R40.0 Somnolence
- R40.1 Stupor
- R40.20 Unspecified coma
- R40.2110 Coma scale, eyes open, never, unspecified time
- R40.2111 Coma scale, eyes open, never, in the field [EMT or ambulance]
- R40.2112 Coma scale, eyes open, never, at arrival to emergency department
- R40.2113 Coma scale, eyes open, never, at hospital admission
- R40.2114 Coma scale, eyes open, never, 24 hours or more after hospital admission
- R40.2120 Coma scale, eyes open, to pain, unspecified time
- R40.2121 Coma scale, eyes open, to pain, in the field [EMT or ambulance]
- R40.2122 Coma scale, eyes open, to pain, at arrival to emergency department
- R40.2123 Coma scale, eyes open, to pain, at hospital admission
- R40.2124 Coma scale, eyes open, to pain, 24 hours or more after hospital admission
- R40.2210 Coma scale, best verbal response, none, unspecified time
- R40.2211 Coma scale, best verbal response, none, in the field [EMT or ambulance]
- R40.2212 Coma scale, best verbal response, none, at arrival to emergency department
- R40.2213 Coma scale, best verbal response, none, at hospital admission
- R40.2214 Coma scale, best verbal response, none, 24 hours or more after hospital admission
- R40.2220 Coma scale, best verbal response, incomprehensible words, unspecified time
- R40.2221 Coma scale, best verbal response, incomprehensible words, in the field [EMT or ambulance]
- R40.2222 Coma scale, best verbal response, incomprehensible words, at arrival to emergency department
- R40.2223 Coma scale, best verbal response, incomprehensible words, at hospital admission
- R40.2224 Coma scale, best verbal response, incomprehensible words, 24 hours or more after hospital admission
- R40.2310 Coma scale, best motor response, none, unspecified time
- R40.2311 Coma scale, best motor response, none, in the field [EMT or ambulance]
- R40.2312 Coma scale, best motor response, none, at arrival to emergency department
- R40.2313 Coma scale, best motor response, none, at hospital admission
- R40.2314 Coma scale, best motor response, none, 24 hours or more after hospital admission
- R40.2320 Coma scale, best motor response, extension, unspecified time
- R40.2321 Coma scale, best motor response, extension, in the field [EMT or ambulance]
- R40.2322 Coma scale, best motor response, extension, at arrival to emergency department
- R40.2323 Coma scale, best motor response, extension, at hospital admission
- R40.2324 Coma scale, best motor response, extension, 24 hours or more after hospital admission
- R40.2340 Coma scale, best motor response, flexion withdrawal, unspecified time
- R40.2341 Coma scale, best motor response, flexion withdrawal, in the field [EMT or ambulance]
- R40.2342 Coma scale, best motor response, flexion withdrawal, at arrival to emergency department
- R40.2343 Coma scale, best motor response, flexion withdrawal, at hospital admission
- R40.2344 Coma scale, best motor response, flexion withdrawal, 24 hours or more after hospital admission
- R40.2A Nontraumatic coma due to underlying condition
- R40.3 Persistent vegetative state
Procedure Codes
Frequently Asked Questions
What is MS-DRG 81?
MS-DRG 81 (Nontraumatic Stupor and Coma without MCC) is a medical DRG in MDC 01 (Diseases & Disorders of the Nervous System). Its FY 2026 relative weight is 0.8956 with a geometric mean length of stay of 2.8 days.
What is the difference between DRG 80, 81?
All 2 share the same base category; the severity of secondary diagnoses separates them: 80 (with MCC), 81 (without MCC). A major complication or comorbidity (MCC) places the case in the highest-weighted DRG of the family; a CC in the middle; neither in the lowest.
How many diagnosis codes group to DRG 81?
44 ICD-10-CM principal diagnosis codes group to this DRG, spanning 3 three-character categories.
What is the relative weight of DRG 81?
The FY 2026 relative weight of this DRG is 0.8956, meaning reimbursement of roughly 0.90 times the average Medicare inpatient case. Multiply by a hospital's blended base rate for the approximate payment.
