2027 ICD-10-CM Diagnosis Code Q97.2Mosaicism, lines with various numbers of X chromosomes

ICD-10-CM Codes›Q00-Q99›Q90-Q99›Q97

ICD-10-CM Q97.2
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Q97.2 is a billable ICD-10-CM diagnosis code for mosaicism, lines with various numbers of X chromosomes. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 742 through 743, 760 through 761. The code is exempt from POA reporting. Coders also document this condition as mosaicism - lines with various numbers of X chromosomes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Chromosomal abnormalities.

Code Identity

ICD-10-CM Code
Q97.2
Billable Status
Yes — Valid for Submission
Code Describes
Mosaicism, lines with various numbers of X chromosomes
Short Description
Mosaicism, lines with various numbers of X chromosomes
Same as the full description in the CMS dataset.
Parent Code
Q97
Other sex chromosome abnormalities, female phenotype, not elsewhere classified

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ90-Q99Chromosomal abnormalities, not elsewhere classified
CategoryQ97Other sex chromosome abnormalities, female phenotype, not elsewhere classified
This CodeQ97.2Mosaicism, lines with various numbers of X chromosomes

Present on Admission (POA)Billing

Q97.2 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Chromosomal abnormalities, not elsewhere classified (Q90-Q99).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Mosaicism - lines with various numbers of X chromosomes
  • Sex chromosome mosaicism

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Q97.2: its own notes plus those printed at Q97, block Q90-Q99, and Chapter 17. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified applies to 6 codes
  • Turner's syndrome (Q96.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block Q90-Q99 Chromosomal abnormalities, not elsewhere classified applies to 74 codes
  • mitochondrial metabolic disorders (E88.4-)
From Chapter 17 (Q00-QA1) Congenital malformations, deformations and chromosomal abnormalities applies to 900 codes
  • inborn errors of metabolism (E70-E88)

Notes

General instructions on how these codes are used.

From Chapter 17 (Q00-QA1) Congenital malformations, deformations and chromosomal abnormalities applies to 900 codes
  • Codes from this chapter are not for use on maternal records

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Q97.2, its category, or a range that includes it.

Excludes1 4

These codes carry an Excludes1 note naming Q97.2: they are not reported together with it, unless the two conditions are unrelated.

  • E25 Adrenogenital disorders
    chromosomal abnormalities (Q90-Q99) names Q90-Q99, which includes this code
  • Block Q50-Q56 Congenital malformations of genital organs
    syndromes associated with anomalies in the number and form of chromosomes (Q90-Q99) names Q90-Q99, which includes this code
  • Q56 Indeterminate sex and pseudohermaphroditism
    pseudohermaphroditism with specified chromosomal anomaly (Q96-Q99) names Q96-Q99, which includes this code
  • Z15 Genetic susceptibility to disease
    chromosomal anomalies (Q90-Q99) names Q90-Q99, which includes this code

Code First 1

These codes say to code first a condition named in the note, and Q97.2 is one of the conditions named.

  • D84.81 Immunodeficiency due to conditions classified elsewhere
    chromosomal abnormalities (Q90-Q99) names Q90-Q99, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MAL009
Chromosomal abnormalities
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Genetic Disorders

Genetic disorders are health conditions caused by changes (also called mutations or variants) in your genes. Genes are parts of DNA found in your cells that carry instructions for how your body grows, develops, and functions. Many genes tell your body how to make proteins, which are needed for your body to work properly.

The full article covers:

  • What are genetic disorders?
  • What causes genetic disorders?
  • What are the types of genetic disorders?
  • What are the different ways a genetic disorder can be inherited?
  • How are genetic disorders diagnosed?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Q97.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
758.81 Oth cond due to sex chrm
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Q97.2Overview

What is the ICD-10 code for mosaicism, lines with various numbers of X chromosomes?

The ICD-10-CM code for mosaicism, lines with various numbers of X chromosomes is Q97.2 (sometimes written as Q972). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is Q97.2 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report mosaicism, lines with various numbers of X chromosomes on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does Q97.2 group to?

When mosaicism, lines with various numbers of X chromosomes is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.7039 to 1.8448 depending on complications. Higher weights mean higher Medicare reimbursement.

Is Q97.2 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for mosaicism, lines with various numbers of X chromosomes on inpatient claims. The code appears in the Chromosomal abnormalities, not elsewhere classified (Q90-Q99) range of the CMS exempt list.

Can Q97.2 be reported with a code from Q96?

Not as a rule. The Excludes1 note at Q97, which applies to Q97.2, lists "Turner's syndrome (Q96.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).