Oth sex chromosome abnormalities, male phenotype, NEC (Q98)
ICD-10 Index
Congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
Chromosomal abnormalities, not elsewhere classified (Q90-Q99)
- Q98 - Oth sex chromosome abnormalities, male phenotype, NEC NON-BILLABLE CODE
- Q98.0 - Klinefelter syndrome karyotype 47, XXY BILLABLE CODE
- Q98.1 - Klinefelter syndrome, male with more than two X chromosomes BILLABLE CODE
- Q98.3 - Other male with 46, XX karyotype BILLABLE CODE
- Q98.4 - Klinefelter syndrome, unspecified BILLABLE CODE
- Q98.5 - Karyotype 47, XYY BILLABLE CODE
- Q98.6 - Male with structurally abnormal sex chromosome BILLABLE CODE
- Q98.7 - Male with sex chromosome mosaicism BILLABLE CODE
- Q98.8 - Other specified sex chromosome abnormalities, male phenotype BILLABLE CODE
- Q98.9 - Sex chromosome abnormality, male phenotype, unspecified BILLABLE CODE
Oth sex chromosome abnormalities, male phenotype, NEC (Q98)
Clinical Information for Oth sex chromosome abnormalities, male phenotype, NEC (Q98)
Klinefelter Syndrome - A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
Gigantism - The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.
Sotos Syndrome - Congenital or postnatal overgrowth syndrome most often in height and occipitofrontal circumference with variable delayed motor and cognitive development. Other associated features include advanced bone age, seizures, NEONATAL JAUNDICE; HYPOTONIA; and SCOLIOSIS. It is also associated with increased risk of developing neoplasms in adulthood. Mutations in the NSD1 protein and its HAPLOINSUFFICIENCY are associated with the syndrome.
Klinefelter Syndrome - A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
Klinefelter Syndrome - A form of male HYPOGONADISM, characterized by the presence of an extra X CHROMOSOME, small TESTES, seminiferous tubule dysgenesis, elevated levels of GONADOTROPINS, low serum TESTOSTERONE, underdeveloped secondary sex characteristics, and male infertility (INFERTILITY, MALE). Patients tend to have long legs and a slim, tall stature. GYNECOMASTIA is present in many of the patients. The classic form has the karyotype 47,XXY. Several karyotype variants include 48,XXYY; 48,XXXY; 49,XXXXY, and mosaic patterns ( 46,XY/47,XXY; 47,XXY/48,XXXY, etc.).
