2027 ICD-10-CM Diagnosis Code M62.50Muscle wasting and atrophy, not elsewhere classified, unspecified site

ICD-10-CM Codes›M00–M99›M60-M63›M62

ICD-10-CM M62.50
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

M62.50 is a billable ICD-10-CM diagnosis code for muscle wasting and atrophy, not elsewhere classified, unspecified site. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 557 through 558. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Muscle disorders.

Code Identity

ICD-10-CM Code
M62.50
Billable Status
Yes — Valid for Submission
Code Describes
Muscle wasting and atrophy, not elsewhere classified, unspecified site
Short Description
Muscle wasting and atrophy, NEC, unsp site
Parent Code
Muscle wasting and atrophy, not elsewhere classified

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM60-M63Disorders of muscles
CategoryM62Other disorders of muscle
This CodeM62.50Muscle wasting and atrophy, not elsewhere classified, unspecified site

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Atrophy of axial muscle
  • Atrophy of perifascicular muscle fiber
  • Atrophy of proximal muscle
  • Atrophy of skeletal muscle fiber
  • Atrophy of skeletal muscle fiber type I
  • Atrophy of skeletal muscle fiber type II
  • Denervation atrophy of muscle
  • Disuse muscle atrophy
  • Disuse syndrome
  • Ischemic muscular atrophy
  • Leg wasted
  • Mild muscle atrophy
  • Moderate muscle atrophy
  • Muscle atrophy
  • Muscular atrophy, ataxia, retinitis pigmentosa, and diabetes mellitus
  • Non-progressive atrophy of muscle
  • Progressive atrophy of distal muscle
  • Progressive muscular atrophy
  • Severe muscle atrophy
  • Severe systemic illness tissue wasting
  • Severe systemic illness-induced skeletal muscle wasting
  • Size of leg - finding
  • X-linked myopathy with postural muscle atrophy

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to M62.50: its own notes plus those printed at M62.5, M62, block M60-M63, and Chapter 13. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From M62.5 Muscle wasting and atrophy, not elsewhere classified applies to 28 codes
From M62 Other disorders of muscle applies to 131 codes
From Block M60-M63 Disorders of muscles applies to 420 codes
  • dermatopolymyositis (M33.-)
  • myopathy in amyloidosis (E85.-)
  • myopathy in polyarteritis nodosa (M30.0)
  • myopathy in rheumatoid arthritis (M05.32)
  • myopathy in scleroderma (M34.-)
  • myopathy in Sjögren's syndrome (M35.03)
  • myopathy in systemic lupus erythematosus (M32.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From M62.5 Muscle wasting and atrophy, not elsewhere classified applies to 28 codes
  • pelvic muscle wasting (N81.84)
From M62 Other disorders of muscle applies to 131 codes
  • nontraumatic hematoma of muscle (M79.81)
From Block M60-M63 Disorders of muscles applies to 420 codes
  • muscular dystrophies and myopathies (G71-G72)
From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Notes

General instructions on how these codes are used.

From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MUS026
Muscle disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Muscle Disorders

Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that can affect muscles. Muscle disorders can cause weakness, pain or even paralysis.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M62.50 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
728.2 Musc disuse atrophy NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About M62.50Overview

What is the ICD-10 code for muscle wasting and atrophy, not elsewhere classified, unspecified site?

The ICD-10-CM code for muscle wasting and atrophy, not elsewhere classified, unspecified site is M62.50 (sometimes written as M6250). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is M62.50 (Muscle wasting and atrophy, not elsewhere classified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report muscle wasting and atrophy, not elsewhere classified, unspecified site on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does M62.50 group to?

When muscle wasting and atrophy, not elsewhere classified, unspecified site is the principal diagnosis on an inpatient stay, it groups to MS-DRG 557, 558, with relative weights from 0.8873 to 1.4883 depending on complications. Higher weights mean higher Medicare reimbursement.

Can M62.50 be reported with G54.5?

Not as a rule. The Excludes1 note at M62.5, which applies to M62.50, lists "neuralgic amyotrophy (G54.5)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of M62.50?

Under the General Equivalence Mappings, muscle wasting and atrophy, not elsewhere classified, unspecified site converts to ICD-9-CM 728.2 (musc disuse atrophy NEC). The mapping is approximate, so confirm the match fits the documentation.