2027 ICD-10-CM Diagnosis Code K76.5Hepatic veno-occlusive disease

ICD-10-CM Codes›K00–K95›K70-K77›K76

ICD-10-CM K76.5
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

K76.5 is a billable ICD-10-CM diagnosis code for hepatic veno-occlusive disease. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 441 through 443. Coders also document this condition as hepatic veno-occlusive disease with immunodeficiency syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified liver disease.

Code Identity

ICD-10-CM Code
K76.5
Billable Status
Yes — Valid for Submission
Code Describes
Hepatic veno-occlusive disease
Short Description
Hepatic veno-occlusive disease
Same as the full description in the CMS dataset.
Parent Code
Other diseases of liver

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK76Other diseases of liver
This CodeK76.5Hepatic veno-occlusive disease

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hepatic veno-occlusive disease with immunodeficiency syndrome
  • Obstruction of visceral vein
  • Severe combined immunodeficiency with low T- and B-cell numbers
  • Veno-occlusive disease of the liver

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to K76.5: its own notes plus those printed at K76, block K70-K77, and Chapter 11. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On K76.5 itself
  • Budd-Chiari syndrome (I82.0)
From Block K70-K77 Diseases of liver applies to 65 codes
  • jaundice NOS (R17)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From K76 Other diseases of liver applies to 13 codes
  • alcoholic liver disease (K70.-)
  • amyloid degeneration of liver (E85.-)
  • cystic disease of liver (congenital) (Q44.6)
  • hepatic vein thrombosis (I82.0)
  • hepatomegaly NOS (R16.0)
  • pigmentary cirrhosis (of liver) (E83.110)
  • portal vein thrombosis (I81)
  • toxic liver disease (K71.-)
From Block K70-K77 Diseases of liver applies to 65 codes
From Chapter 11 (K00-K95) Diseases of the digestive system applies to 863 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name K76.5, its category, or a range that includes it.

Use Additional Code 2

These codes say to use an additional code from the note, and K76.5 is one of the codes named.

  • M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]
    hepatic veno-occlusive disease (K76.5)
  • M31.11 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]
    sinusoidal obstruction syndrome (K76.5)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hepatic Veno-Occlusive Disease

    liver disease that is caused by injuries to the endothelial cells of the vessels and subendothelial edema, but not by thrombosis. extracellular matrix, rich in fibronectins, is usually deposited around the hepatic veins leading to venous outflow occlusion and sinusoidal obstruction.

Patient EducationClinical

Liver Diseases

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K76.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
573.8 Liver disorders NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About K76.5Overview

What is the ICD-10 code for hepatic veno-occlusive disease?

The ICD-10-CM code for hepatic veno-occlusive disease is K76.5 (sometimes written as K765). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is K76.5 (Other diseases of liver) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hepatic veno-occlusive disease on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does K76.5 group to?

When hepatic veno-occlusive disease is the principal diagnosis on an inpatient stay, it groups to MS-DRG 442, 441, 443, with relative weights from 0.6890 to 1.8226 depending on complications. Higher weights mean higher Medicare reimbursement.

Can K76.5 be reported with I82.0?

Not as a rule. The Excludes1 note on K76.5 lists "Budd-Chiari syndrome (I82.0)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of K76.5?

Under the General Equivalence Mappings, hepatic veno-occlusive disease converts to ICD-9-CM 573.8 (liver disorders NEC). The mapping is approximate, so confirm the match fits the documentation.