2026 ICD-10-CM Diagnosis Code K71.10Toxic liver disease with hepatic necrosis, without coma

ICD-10-CM Codes›K00–K95›K70-K77›K71

ICD-10-CM K71.10
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K71.10 is a billable ICD-10-CM diagnosis code for toxic liver disease with hepatic necrosis, without coma. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 441 through 443. Coders also document this condition as acute hepatic failure. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Other specified and unspecified liver disease.

Code Identity

ICD-10-CM Code
K71.10
Billable Status
Yes — Valid for Submission
Code Describes
Toxic liver disease with hepatic necrosis, without coma
Short Description
Toxic liver disease with hepatic necrosis, without coma
Same as the full description in the CMS dataset.
Parent Code
K71.1
Toxic liver disease with hepatic necrosis

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK71Toxic liver disease
This CodeK71.10Toxic liver disease with hepatic necrosis, without coma

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute hepatic failure
  • Acute hepatic failure due to drugs
  • Drug-induced hepatic necrosis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Disease, diseased
      • liver (chronic) (organic)
        • toxic
          • with
            • hepatic necrosis
    • Failure, failed
      • hepatic
        • acute or subacute
          • due to drugs
    • Failure, failed
      • hepatic
        • chronic
          • due to drugs (acute) (subacute) (chronic)
    • Failure, failed
      • hepatic
        • due to drugs (acute) (subacute) (chronic)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Liver Diseases

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K71.10 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
573.3 Hepatitis NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K71.10Overview

Is K71.10 (Toxic liver disease with hepatic necrosis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic liver disease with hepatic necrosis, without coma on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K71.10 group to?

When toxic liver disease with hepatic necrosis, without coma is the principal diagnosis on an inpatient stay, it groups to MS-DRG 441, 442, 443, with relative weights from 0.6997 to 1.7947 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of K71.10?

Under the General Equivalence Mappings, toxic liver disease with hepatic necrosis, without coma converts to ICD-9-CM 573.3 (hepatitis NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.