2027 ICD-10-CM Diagnosis Code J84.841Neuroendocrine cell hyperplasia of infancy

ICD-10-CM Codes›J00–J99›J80-J84›J84

ICD-10-CM J84.841
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

J84.841 is a billable ICD-10-CM diagnosis code for neuroendocrine cell hyperplasia of infancy. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 196 through 198, 791, 793. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 78 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified lower respiratory disease.

J84.841 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 112 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 112, ESRD (V21) category 112, ESRD (V24) category 112, and RxHCC Part D (V08) category 227 for payment year 2027.

Code Identity

ICD-10-CM Code
J84.841
Billable Status
Yes — Valid for Submission
Code Describes
Neuroendocrine cell hyperplasia of infancy
Short Description
Neuroendocrine cell hyperplasia of infancy
Same as the full description in the CMS dataset.
Parent Code
Other interstitial lung diseases of childhood

Code Classification

ChapterJ00–J99Diseases of the respiratory system
SectionJ80-J84Other respiratory diseases principally affecting the interstitium
CategoryJ84Other interstitial pulmonary diseases
This CodeJ84.841Neuroendocrine cell hyperplasia of infancy

Medicare Risk Adjustment (HCC)Billing

J84.841 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
Dropped in V28 see all codes that no longer risk-adjust
Prior Model (CMS-HCC V24)
HCC 112
V24 retired last contributed to a Medicare Advantage risk score in payment year 2025
Other CMS Models
PACE (CMS-HCC V22): HCC 112 · ESRD (V21): HCC 112 · ESRD (V24): HCC 112
ESRD V21 weights: 0.066 dialysis, 0.281–0.299 functioning graft · ESRD V24 weights: 0.058 dialysis, 0.080–0.256 functioning graft
Part D (RxHCC)
RxHCC 227 — Pulmonary Fibrosis, Except Idiopathic
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Neuroendocrine cell hyperplasia of infancy

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to J84.841: its own notes plus those printed at J84.8, J84, and Chapter 10. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From J84.8 Other specified interstitial pulmonary diseases applies to 8 codes
  • exogenous lipoid pneumonia (J69.1)
  • unspecified lipoid pneumonia (J69.1)
From J84 Other interstitial pulmonary diseases applies to 24 codes
  • drug-induced interstitial lung disorders (J70.2-J70.4)
  • interstitial emphysema (J98.2)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From J84 Other interstitial pulmonary diseases applies to 24 codes
  • lung diseases due to external agents (J60-J70)
From Chapter 10 (J00-J99) Diseases of the respiratory system applies to 366 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • smoke inhalation (T59.81-)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 10 (J00-J99) Diseases of the respiratory system applies to 366 codes
  • code, where applicable, to identify:
  • exposure to environmental tobacco smoke (Z77.22)
  • exposure to tobacco smoke in the perinatal period (P96.81)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

From J84 Other interstitial pulmonary diseases applies to 24 codes
  • if applicable, associated condition

Notes

General instructions on how these codes are used.

From Chapter 10 (J00-J99) Diseases of the respiratory system applies to 366 codes
  • When a respiratory condition is described as occurring in more than one site and is not specifically indexed, it should be classified to the lower anatomic site (e.g. tracheobronchitis to bronchitis in J40).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name J84.841, its category, or a range that includes it.

Code Also 1

These codes say J84.841 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • I27.23 Pulmonary hypertension due to lung diseases and hypoxia
    interstitial lung disease (J84.-) names J84.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR RSP016
Other specified and unspecified lower respiratory disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Neuroendocrine Cell Hyperplasia of Infancy

    a form of interstitial lung disease characterized by increased numbers of pulmonary neuroendocrine cells, typically presenting in the first year of life with persistent tachypnea, retractions, crackles and hypoxemia that has a highly specific chest ct pattern that includes ground-glass opacities and air-trapping.

Patient EducationClinical

Interstitial Lung Diseases

Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. The inflammation and scarring make it hard to get enough oxygen. The scarring is called pulmonary fibrosis.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert J84.841 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
516.61 Neuroend cell hyprpl inf
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About J84.841Overview

What is the ICD-10 code for neuroendocrine cell hyperplasia of infancy?

The ICD-10-CM code for neuroendocrine cell hyperplasia of infancy is J84.841 (sometimes written as J84841). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is J84.841 (Other interstitial lung diseases of childhood) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neuroendocrine cell hyperplasia of infancy on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does J84.841 group to?

When neuroendocrine cell hyperplasia of infancy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 198, 197, 196, with relative weights from 0.7256 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.

Is J84.841 a CC or MCC?

CMS lists J84.841 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 78 closely related codes in its exclusion list.

Can J84.841 be reported with J69.1?

Not as a rule. The Excludes1 note at J84.8, which applies to J84.841, lists "exogenous lipoid pneumonia (J69.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does J84.841 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage. J84.841 mapped to HCC 112 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 112 (Fibrosis of Lung and Other Chronic Lung Disorders), ESRD (V21) category 112 (Fibrosis of Lung and Other Chronic Lung Disorders), ESRD (V24) category 112 (Fibrosis of Lung and Other Chronic Lung Disorders), and RxHCC Part D (V08) category 227 (Pulmonary Fibrosis, Except Idiopathic).