2026 ICD-10-CM Diagnosis Code I88.0Nonspecific mesenteric lymphadenitis

ICD-10-CM Codes›I00–I99›I80-I89›I88

ICD-10-CM I88.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I88.0 is a billable ICD-10-CM diagnosis code for nonspecific mesenteric lymphadenitis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 393 through 395. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified diseases of veins and lymphatics.

Code Identity

ICD-10-CM Code
I88.0
Billable Status
Yes — Valid for Submission
Code Describes
Nonspecific mesenteric lymphadenitis
Short Description
Nonspecific mesenteric lymphadenitis
Same as the full description in the CMS dataset.
Parent Code
I88
Nonspecific lymphadenitis

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI80-I89Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
CategoryI88Nonspecific lymphadenitis
This CodeI88.0Nonspecific mesenteric lymphadenitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute lymphadenitis of trunk
  • Acute mesenteric adenitis
  • Chronic lymphadenitis
  • Chronic mesenteric lymphadenitis
  • Infection by Pasteurella multocida
  • Inferior mesenteric lymphadenopathy
  • Juxtaintestinal lymphadenopathy
  • Masshoff's syndrome
  • Mesenteric adenitis caused by Pasteurella multocida
  • Mesenteric lymphadenitis
  • Mesenteric lymphadenopathy
  • Nonspecific mesenteric adenitis
  • Pasteurella mesenteric adenitis
  • Pseudotuberculosis
  • Sigmoid lymphadenopathy
  • Superior mesenteric lymphadenopathy

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Mesenteric lymphadenitis (acute)(chronic)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Abscess(connective tissue) (embolic) (fistulous) (infective) (metastatic) (multiple) (pernicious) (pyogenic) (septic)
      • lymph, lymphatic, gland or node (acute)
        • mesentery
    • Adenitis
      • mesenteric (acute) (chronic) (nonspecific) (subacute)
    • Brennemann's syndrome
    • Infection, infected, infective(opportunistic)
      • lymph gland
        • mesenteric
    • Infection, infected, infective(opportunistic)
      • mesenteric lymph nodes or glands NEC
    • Lymphadenitis
      • chronic
        • mesenteric
    • Lymphadenitis
      • mesenteric (acute) (chronic) (nonspecific) (subacute)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR039
Other specified diseases of veins and lymphatics
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Mesenteric Lymphadenitis

    inflammation of lymph nodes in the mesentery.

  • Chronic Lymphadenitis

    inflammation of the lymph nodes that is chronic in nature.

  • Mesenteric Lymphadenitis

    inflammation of the mesenteric lymph nodes.

Patient EducationClinical

Lymphatic Diseases

The lymphatic system is a network of tissues and organs. It is made up of:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I88.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
289.2 Mesenteric lymphadenitis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I88.0Overview

Is I88.0 (Nonspecific lymphadenitis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report nonspecific mesenteric lymphadenitis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I88.0 group to?

When nonspecific mesenteric lymphadenitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 393, 394, 395, with relative weights from 0.6490 to 1.5993 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of I88.0?

Under the General Equivalence Mappings, nonspecific mesenteric lymphadenitis converts to ICD-9-CM 289.2 (mesenteric lymphadenitis). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.