2027 ICD-10-CM Diagnosis Code I88.0Nonspecific mesenteric lymphadenitis
ICD-10-CM Codes›I00–I99›I80-I89›I88
- Billable — Valid for Submission
- Not Chronic
I88.0 is a billable ICD-10-CM diagnosis code for nonspecific mesenteric lymphadenitis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 393 through 395. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified diseases of veins and lymphatics.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acute lymphadenitis of trunk
- Acute mesenteric adenitis
- Chronic lymphadenitis
- Chronic mesenteric lymphadenitis
- Infection by Pasteurella multocida
- Inferior mesenteric lymphadenopathy
- Juxtaintestinal lymphadenopathy
- Masshoff's syndrome
- Mesenteric adenitis caused by Pasteurella multocida
- Mesenteric lymphadenitis
- Mesenteric lymphadenopathy
- Nonspecific mesenteric adenitis
- Pasteurella mesenteric adenitis
- Pseudotuberculosis
- Sigmoid lymphadenopathy
- Superior mesenteric lymphadenopathy
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to I88.0: its own notes plus those printed at I88 and Chapter 9. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Mesenteric lymphadenitis (acute)(chronic)
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
- systemic connective tissue disorders (M30-M36)
- transient cerebral ischemic attacks and related syndromes (G45.-)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name I88.0, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming I88.0: they are not reported together with it, unless the two conditions are unrelated.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Abscess (connective tissue) (embolic) (fistulous) (infective) (metastatic) (multiple) (pernicious) (pyogenic) (septic) L02.91
lymph, lymphatic, gland or node (acute) See Also: Lymphadenitis, acute;
mesentery I88.0
Adenitis See Also: Lymphadenitis;
Brennemann's syndrome I88.0
Infection, infected, infective (opportunistic) B99.9
lymph gland See Also: Lymphadenitis, acute;
mesenteric I88.0
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Lymphatic Diseases
The lymphatic system is a network of tissues and organs. It is made up of:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert I88.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About I88.0Overview
What is the ICD-10 code for nonspecific mesenteric lymphadenitis?
The ICD-10-CM code for nonspecific mesenteric lymphadenitis is I88.0 (sometimes written as I880). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is I88.0 (Nonspecific lymphadenitis) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report nonspecific mesenteric lymphadenitis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does I88.0 group to?
When nonspecific mesenteric lymphadenitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 394, 395, 393, with relative weights from 0.6379 to 1.5877 depending on complications. Higher weights mean higher Medicare reimbursement.
Can I88.0 be reported with a code from L04?
Not as a rule. The Excludes1 note at I88, which applies to I88.0, lists "acute lymphadenitis, except mesenteric (L04.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of I88.0?
Under the General Equivalence Mappings, nonspecific mesenteric lymphadenitis converts to ICD-9-CM 289.2 (mesenteric lymphadenitis). The mapping is a direct match.
