1. Home
  2. ICD-10-CM Codes
  3. I00–I99
  4. I80-I89
  5. I88
  6. 2025 ICD-10-CM Code I88

2025 ICD-10-CM Diagnosis Code I88

Nonspecific lymphadenitis

ICD-10-CM Code:
I88
ICD-10 Code for:
Nonspecific lymphadenitis
Is Billable?
Not Valid for Submission
Code Navigator:

I88 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of nonspecific lymphadenitis. The code is not specific and is NOT valid for the year 2025 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Nonspecific lymphadenitis

Non-specific codes like I88 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for nonspecific lymphadenitis:

  • Use I88.0 for Nonspecific mesenteric lymphadenitis - BILLABLE CODE

  • Use I88.1 for Chronic lymphadenitis, except mesenteric - BILLABLE CODE

  • Use I88.8 for Other nonspecific lymphadenitis - BILLABLE CODE

  • Use I88.9 for Nonspecific lymphadenitis, unspecified - BILLABLE CODE

Code Classification

  • Diseases of the circulatory system
    I00–I99
    • Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
      I80-I89
      • Nonspecific lymphadenitis
        I88

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • acute lymphadenitis, except mesenteric L04
  • enlarged lymph nodes NOS R59
  • human immunodeficiency virus HIV disease resulting in generalized lymphadenopathy B20

Patient Education


Lymphatic Diseases

The lymphatic system is a network of tissues and organs. It is made up of:

  • Lymph - a fluid that contains white blood cells that defend against germs
  • Lymph vessels - vessels that carry lymph throughout your body. They are different from blood vessels.
  • Lymph nodes - glands found throughout the lymph vessels. Along with your spleen, these nodes are where white blood cells fight infection.

Your bone marrow and thymus produce the cells in lymph. They are part of the system, too.

The lymphatic system clears away infection and keeps your body fluids in balance. If it's not working properly, fluid builds in your tissues and causes swelling, called lymphedema. Other lymphatic system problems can include infections, blockage, and cancer.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.