Nonspecific lymphadenitis (I88) ICD-10-CM
The I88 code range covers nonspecific lymphadenitis with 5 ICD-10-CM diagnosis codes. 4 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the I88 Range 5 codes · 4 billable
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the I88 range.
Histiocytic Necrotizing Lymphadenitis
Development of lesions in the lymph node characterized by infiltration of the cortex or paracortex by large collections of proliferating histiocytes and complete or, more often, incomplete necrosis of lymphoid tissue.
Lymphadenitis
Inflammation of the lymph nodes.
Mesenteric Lymphadenitis
INFLAMMATION of LYMPH NODES in the MESENTERY.
Tuberculosis, Lymph Node
Infection of the lymph nodes by tuberculosis. Tuberculous infection of the cervical lymph nodes is scrofula.
About the I88 Code Range
ICD-10 code I88 and its subcodes classify various forms of nonspecific lymphadenitis, a condition involving inflammation of lymph nodes without a clearly identified cause. These codes guide accurate documentation of nonspecific lymph node inflammations in different anatomical regions.
The main code I88 covers general nonspecific lymphadenitis. Code I88.0 specifies nonspecific mesenteric lymphadenitis, which is inflammation of lymph nodes in the mesentery, also known under terms like superior or inferior mesenteric lymphadenopathy and conditions such as Masshoff's syndrome or Pasteurella multocida infection. I88.1 identifies chronic lymphadenitis excluding mesenteric sites, including axillary, inguinal, and cervical lymphadenopathy. Code I88.8 relates to other nonspecific types like histiocytic necrotizing or dermatopathic lymphadenitis. Lastly, I88.9 is used for unspecified nonspecific lymphadenitis, which may include conditions associated with Toxoplasma gondii infection or PFAPA syndrome. These ICD-10 codes enable precise classification of lymph node inflammations for clinical and billing purposes and help differentiate among commonly confused terms like mesenteric adenitis versus generalized lymphadenitis.
Questions About This Page
How many billable codes are in the I88 range?
Of the 5 codes in this range, 4 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the I88 range classify?
The range classifies nonspecific lymphadenitis. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
