2026 ICD-10-CM Diagnosis Code I82.221Chronic embolism and thrombosis of inferior vena cava

ICD-10-CM CodesI00–I99I80-I89I82

ICD-10-CM I82.221
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I82.221 is a billable ICD-10-CM diagnosis code for chronic embolism and thrombosis of inferior vena cava. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 299 through 301. Coders also document this condition as chronic thrombosis of inferior vena cava. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Chronic phlebitis; thrombophlebitis and thromboembolism.

Code Identity

ICD-10-CM Code
I82.221
Billable Status
Yes — Valid for Submission
Code Describes
Chronic embolism and thrombosis of inferior vena cava
Short Description
Chronic embolism and thrombosis of inferior vena cava
Same as the full description in the CMS dataset.
Parent Code
Embolism and thrombosis of inferior vena cava

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI80-I89Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
CategoryI82Other venous embolism and thrombosis
This CodeI82.221Chronic embolism and thrombosis of inferior vena cava

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chronic thrombosis of inferior vena cava
  • Thrombosis of inferior vena cava
  • Thrombosis of vena cava

Index to Diseases and InjuriesGuidance

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Embolism(multiple) (paradoxical)
      • vena cava
        • inferior (acute)
          • chronic
    • Thrombosis, thrombotic(bland) (multiple) (progressive) (silent) (vessel)
      • vena cava
        • inferior
          • chronic

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR034
Chronic phlebitis; thrombophlebitis and thromboembolism
Default principal diagnosis: inpatient Yes · outpatient Yes

Convert I82.221 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
453.2 Oth inf vena cava thromb
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I82.221Overview

Is I82.221 (Embolism and thrombosis of inferior vena cava) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report chronic embolism and thrombosis of inferior vena cava on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I82.221 group to?

When chronic embolism and thrombosis of inferior vena cava is the principal diagnosis on an inpatient stay, it groups to MS-DRG 299, 300, 301, with relative weights from 0.7197 to 1.6327 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of I82.221?

Under the General Equivalence Mappings, chronic embolism and thrombosis of inferior vena cava converts to ICD-9-CM 453.2 (oth inf vena cava thromb). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.