2027 ICD-10-CM Diagnosis Code I49.49Other premature depolarization

ICD-10-CM Codes›I00–I99›I30-I5A›I49

ICD-10-CM I49.49
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

I49.49 is a billable ICD-10-CM diagnosis code for other premature depolarization. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 308 through 310. Coders also document this condition as atrial parasystole. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Cardiac dysrhythmias.

This medical diagnosis code is frequently used in Cardiology medical specialties to designate conditions such cardiac arrhythmias (other).

Code Identity

ICD-10-CM Code
I49.49
Billable Status
Yes — Valid for Submission
Code Describes
Other premature depolarization
Short Description
Other premature depolarization
Same as the full description in the CMS dataset.
Parent Code
I49.4
Other and unspecified premature depolarization

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI30-I5AOther forms of heart disease
CategoryI49Other cardiac arrhythmias
This CodeI49.49Other premature depolarization

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Atrial parasystole
  • ECG: ectopic beats
  • ECG: extrasystole
  • Extrasystoles, short stature, hyperpigmentation, microcephaly syndrome
  • Multifocal premature beats
  • Parasystole

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to I49.49: its own notes plus those printed at I49 and Chapter 9. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Ectopic beats
  • Extrasystoles
  • Extrasystolic arrhythmias
  • Premature contractions

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From I49 Other cardiac arrhythmias applies to 12 codes
  • bradycardia NOS (R00.1)
  • neonatal dysrhythmia (P29.1-)
  • sinoatrial bradycardia (R00.1)
  • sinus bradycardia (R00.1)
  • vagal bradycardia (R00.1)
From Chapter 9 (I00-I99) Diseases of the circulatory system applies to 1,433 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • transient cerebral ischemic attacks and related syndromes (G45.-)

Code First

The underlying condition named in the note is sequenced before this code.

From I49 Other cardiac arrhythmias applies to 12 codes
  • cardiac arrhythmia complicating:
  • abortion or ectopic or molar pregnancy (O00-O07, O08.8)
  • obstetric surgery and procedures (O75.4)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name I49.49, its category, or a range that includes it.

Excludes2 1

These codes carry an Excludes2 note naming I49.49: its condition is not part of those codes, and both may be reported when the patient has both.

  • R00 Abnormalities of heart beat
    specified arrhythmias (I47-I49) names I47-I49, which includes this code

Code Also 1

These codes say I49.49 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • M35.81 Multisystem inflammatory syndrome
    cardiac arrhythmia (I47-I49.-) names I47-I49, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR017
Cardiac dysrhythmias
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Cardiac Complexes, Premature

    a group of cardiac arrhythmias in which the cardiac contractions are not initiated at the sinoatrial node. they include both atrial and ventricular premature beats, and are also known as extra or ectopic heartbeats. their frequency is increased in heart diseases.

Patient EducationClinical

Arrhythmia

An arrhythmia is a problem with the rate or rhythm of your heartbeat. Your heart beats too quickly, too slowly, or with an irregular pattern. Changes in the electrical signals that control your heartbeat cause arrhythmias.

The full article covers:

  • What is an arrhythmia?
  • What causes an arrhythmia?
  • What are the symptoms of an arrhythmia?
  • How is an arrhythmia diagnosed?
  • What are the treatments for an arrhythmia?
  • Can arrhythmias be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I49.49 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
427.69 Premature beats NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About I49.49Overview

What is the ICD-10 code for other premature depolarization?

The ICD-10-CM code for other premature depolarization is I49.49 (sometimes written as I4949). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is I49.49 (Other and unspecified premature depolarization) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other premature depolarization on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does I49.49 group to?

When other premature depolarization is the principal diagnosis on an inpatient stay, it groups to MS-DRG 309, 310, 308, with relative weights from 0.5686 to 1.1809 depending on complications. Higher weights mean higher Medicare reimbursement.

What is coded first with I49.49?

The Code First note at I49, which applies to I49.49, reads: cardiac arrhythmia complicating: abortion or ectopic or molar pregnancy (O00-O07, O08.8); obstetric surgery and procedures (O75.4). When one of these applies, it is sequenced before I49.49.

What is the ICD-9 equivalent of I49.49?

Under the General Equivalence Mappings, other premature depolarization converts to ICD-9-CM 427.69 (premature beats NEC). The mapping is approximate, so confirm the match fits the documentation.