2026 ICD-10-CM Diagnosis Code I49.49Other premature depolarization

ICD-10-CM Codes›I00–I99›I30-I5A›I49

ICD-10-CM I49.49
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I49.49 is a billable ICD-10-CM diagnosis code for other premature depolarization. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 308 through 310. Coders also document this condition as atrial parasystole. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Cardiac dysrhythmias.

This medical diagnosis code is frequently used in Cardiology medical specialties to designate conditions such cardiac arrhythmias (other).

Code Identity

ICD-10-CM Code
I49.49
Billable Status
Yes — Valid for Submission
Code Describes
Other premature depolarization
Short Description
Other premature depolarization
Same as the full description in the CMS dataset.
Parent Code
I49.4
Other and unspecified premature depolarization

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI30-I5AOther forms of heart disease
CategoryI49Other cardiac arrhythmias
This CodeI49.49Other premature depolarization

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Atrial parasystole
  • ECG: ectopic beats
  • ECG: extrasystole
  • Extrasystoles, short stature, hyperpigmentation, microcephaly syndrome
  • Multifocal premature beats
  • Parasystole

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Ectopic beats
  • Extrasystoles
  • Extrasystolic arrhythmias
  • Premature contractions

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Arrhythmia(auricle)(cardiac)(juvenile)(nodal)(reflex)(supraventricular)(transitory)(ventricle)
      • extrasystolic
    • Beat(s)
      • ectopic
    • Beat(s)
      • escaped, heart
    • Contraction(s), contracture, contracted
      • premature
        • auriculoventricular
    • Contraction(s), contracture, contracted
      • premature
        • heart
    • Depolarization, premature
      • specified NEC
    • Ectopic, ectopia(congenital)
      • beats
    • Extrasystoles(supraventricular)
    • Premature
      • contraction
        • auriculoventricular
    • Premature
      • contraction
        • heart (extrasystole)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR017
Cardiac dysrhythmias
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Parasystole

    a cardiac arrhythmia that is caused by interaction of two independently initiated cardiac impulses of different rates from two separate foci. generally one focus is the sinoatrial node, the normal pacemaker. the ectopic focus is usually in the heart ventricle but can be in the heart atrium or the atrioventricular node. modulation of the parasystolic rhythm by the sinus rhythm depends on the completeness of entrance block surrounding the parasystolic focus.

Patient EducationClinical

Arrhythmia

An arrhythmia is a problem with the rate or rhythm of your heartbeat. Your heart beats too quickly, too slowly, or with an irregular pattern. Changes in the electrical signals that control your heartbeat cause arrhythmias.

The full article covers:

  • What is an arrhythmia?
  • What causes an arrhythmia?
  • What are the symptoms of an arrhythmia?
  • How is an arrhythmia diagnosed?
  • What are the treatments for an arrhythmia?
  • Can arrhythmias be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I49.49 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
427.69 Premature beats NEC
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I49.49Overview

Is I49.49 (Other and unspecified premature depolarization) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other premature depolarization on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I49.49 group to?

When other premature depolarization is the principal diagnosis on an inpatient stay, it groups to MS-DRG 308, 309, 310, with relative weights from 0.5661 to 1.2040 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of I49.49?

Under the General Equivalence Mappings, other premature depolarization converts to ICD-9-CM 427.69 (premature beats NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.