2027 ICD-10-CM Diagnosis Code G62.81Critical illness polyneuropathy

ICD-10-CM Codes›G00–G99›G60-G65›G62

ICD-10-CM G62.81
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G62.81 is a billable ICD-10-CM diagnosis code for critical illness polyneuropathy. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 73 through 74. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 110 closely related codes. Coders also document this condition as acute motor axonal neuropathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Polyneuropathies.

G62.81 no longer risk-adjusts for Medicare Advantage: it mapped to HCC 75 under the retired CMS-HCC V24 model through payment year 2025 but maps to no category in the live V28 model. It still risk-adjusts in the PACE (CMS-HCC V22) category 75, ESRD (V21) category 75, ESRD (V24) category 75, and RxHCC Part D (V08) category 158 for payment year 2027.

Code Identity

ICD-10-CM Code
G62.81
Billable Status
Yes — Valid for Submission
Code Describes
Critical illness polyneuropathy
Short Description
Critical illness polyneuropathy
Same as the full description in the CMS dataset.
Parent Code
G62.8
Other specified polyneuropathies

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG60-G65Polyneuropathies and other disorders of the peripheral nervous system
CategoryG62Other and unspecified polyneuropathies
This CodeG62.81Critical illness polyneuropathy

Medicare Risk Adjustment (HCC)Billing

G62.81 no longer risk-adjusts for Medicare Advantage: it maps to no payment category in the live CMS-HCC V28 model, although it still risk-adjusts in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
Dropped in V28 see all codes that no longer risk-adjust
Prior Model (CMS-HCC V24)
HCC 75
V24 retired last contributed to a Medicare Advantage risk score in payment year 2025
Other CMS Models
PACE (CMS-HCC V22): HCC 75 · ESRD (V21): HCC 75 · ESRD (V24): HCC 75
ESRD V21 weights: 0.059 dialysis, 0.284–0.323 functioning graft · ESRD V24 weights: 0.074 dialysis, 0.344–0.599 functioning graft
Part D (RxHCC)
RxHCC 158 — Inflammatory and Toxic Neuropathy
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acute motor axonal neuropathy
  • Acute motor sensory axonal neuropathy
  • Critical illness polyneuropathy
  • Guillain-Barré syndrome

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G62.81: its own notes plus those printed at block G60-G65 and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Acute motor neuropathy

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block G60-G65 Polyneuropathies and other disorders of the peripheral nervous system applies to 24 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G62.81, its category, or a range that includes it.

Use Additional Code 2

These codes say to use an additional code from the note, and G62.81 is one of the codes named.

  • R65.11 Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction
    critical illness polyneuropathy (G62.81)
  • R65.2 Severe sepsis
    critical illness polyneuropathy (G62.81)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS015
Polyneuropathies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Critical Illness Polyneuropathy

    polyneuropathy arising in intensive care unit patients. it is a common complication of severe sepsis and is thought to represent a neurologic manifestation of systemic inflammatory response syndrome (sirs).

Patient EducationClinical

Peripheral Nerve Disorders

Nerves are like wires that carry messages back and forth between your brain and your body. Your peripheral nerves branch off from your brain and spinal cord and connect to all parts of your body, including your muscles and organs.

The full article covers:

  • What are peripheral nerves?
  • What are peripheral nerve disorders?
  • What causes peripheral nerve disorders?
  • What are the symptoms of peripheral nerve disorders?
  • How are peripheral nerve disorders diagnosed?
  • What are the treatments for peripheral nerve disorders?
  • Can peripheral nerve disorders be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G62.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
357.82 Crit illness neuropathy
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G62.81Overview

What is the ICD-10 code for critical illness polyneuropathy?

The ICD-10-CM code for critical illness polyneuropathy is G62.81 (sometimes written as G6281). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G62.81 (Other specified polyneuropathies) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report critical illness polyneuropathy on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G62.81 group to?

When critical illness polyneuropathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 74, 73, with relative weights from 1.0172 to 1.5773 depending on complications. Higher weights mean higher Medicare reimbursement.

Is G62.81 a CC or MCC?

CMS lists G62.81 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 110 closely related codes in its exclusion list.

Can G62.81 be reported with M79.2?

Not as a rule. The Excludes1 note at block G60-G65, which applies to G62.81, lists "neuralgia NOS (M79.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does G62.81 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage. G62.81 mapped to HCC 75 in the retired CMS-HCC V24 model, which last determined payment in 2025, but it maps to no category in the live V28 model; see all codes that no longer risk-adjust. It still risk-adjusts in the PACE (CMS-HCC V22) category 75 (Myasthenia Gravis/Myoneural Disorders and Guillain-Barre Syndrome/Inflammatory and Toxic Neuropathy), ESRD (V21) category 75 (Polyneuropathy), ESRD (V24) category 75 (Myasthenia Gravis/Myoneural Disorders and Guillain-Barre Syndrome/Inflammatory and Toxic Neuropathy), and RxHCC Part D (V08) category 158 (Inflammatory and Toxic Neuropathy).