2027 ICD-10-CM Diagnosis Code G25.3Myoclonus

ICD-10-CM Codes›G00–G99›G20-G26›G25

ICD-10-CM G25.3
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G25.3 is a billable ICD-10-CM diagnosis code for myoclonus. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 91 through 93. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (often hereditary or degenerative).

Code Identity

ICD-10-CM Code
G25.3
Billable Status
Yes — Valid for Submission
Code Describes
Myoclonus
Short Description
Myoclonus
Same as the full description in the CMS dataset.
Parent Code
G25
Other extrapyramidal and movement disorders

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG20-G26Extrapyramidal and movement disorders
CategoryG25Other extrapyramidal and movement disorders
This CodeG25.3Myoclonus

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Autoimmune generalized polymyoclonus
  • Autoimmune movement disorder
  • Autoimmune opsoclonus myoclonus
  • Benign neonatal sleep myoclonus
  • Brainstem myoclonus
  • Cerebral cortex myoclonus
  • Cochlear nerve disorder
  • Dissociative neurological symptom disorder co-occurrent with myoclonus
  • Drug-induced myoclonus
  • Dysphonia of palatopharyngolaryngeal myoclonus
  • Familial cortical myoclonus
  • Familial essential myoclonus
  • Focal myoclonus
  • Hyoid myoclonus
  • Hyperexplexia
  • Hypnic jerk
  • Insomnia due to periodic limb movement disorder
  • Intention myoclonus
  • Juvenile cerebellar degeneration AND myoclonus
  • Myoclonic disorder
  • Myoclonic disorder due to dementia
  • Myoclonic disorder due to hepatic failure
  • Myoclonic disorder due to mitochondrial disorder
  • Myoclonic disorder due to neuronal ceroid lipofuscinosis
  • Myoclonic disorder due to sialidosis
  • Myoclonic disorder due to uremia
  • Myoclonus
  • Myoclonus associated with fever
  • Myoclonus of tensor tympani muscle
  • Myoclonus, cerebellar ataxia, deafness syndrome
  • Neural hearing loss
  • Non-epileptic myoclonus
  • Oculopalatal myoclonus
  • Opsoclonus-myoclonus syndrome
  • Palatal myoclonus
  • Palatal-tympanic myoclonus
  • Paramyoclonus multiplex
  • Paraneoplastic myoclonus
  • Paraneoplastic opsoclonus myoclonus syndrome
  • Pendular nystagmus
  • Periodic leg movements of sleep
  • Periodic limb movement disorder
  • Photomyoclonus, diabetes mellitus, deafness, nephropathy and cerebral dysfunction
  • Post-anoxic myoclonus
  • Postencephalitic myoclonus
  • Progressive cerebellar ataxia with palatal myoclonus
  • Propriospinal myoclonus at sleep onset
  • Propriospinal myoclonus at sleep onset in infancy
  • Segmental cord myoclonus
  • Segmental myoclonus
  • Sleep related movement disorder
  • Spinal cord myoclonus
  • Spontaneous eye movements in coma
  • Sporadic hyperekplexia
  • Stapedial finding
  • Stapedial myoclonus
  • Vertical myoclonus

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G25.3: its own notes plus those printed at G25 and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Drug-induced myoclonus
  • Palatal myoclonus

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From G25 Other extrapyramidal and movement disorders applies to 16 codes
  • sleep related movement disorders (G47.6-)
From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G25.3, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming G25.3: they are not reported together with it, unless the two conditions are unrelated.

  • R25 Abnormal involuntary movements
    specific movement disorders (G20-G26) names G20-G26, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming G25.3: its condition is not part of those codes, and both may be reported when the patient has both.

  • F98.4 Stereotyped movement disorders
    movement disorders of organic origin (G20-G25) names G20-G25, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS006
Other nervous system disorders (often hereditary or degenerative)
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Myoclonus

    involuntary shock-like contractions, irregular in rhythm and amplitude, followed by relaxation, of a muscle or a group of muscles. this condition may be a feature of some central nervous system diseases; (e.g., epilepsy, myoclonic). nocturnal myoclonus is the principal feature of the nocturnal myoclonus syndrome. (from adams et al., principles of neurology, 6th ed, pp102-3).

Patient EducationClinical

Movement Disorders

Movement disorders are neurologic conditions that cause problems with movement, such as:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G25.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
333.2 Myoclonus
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G25.3Overview

What is the ICD-10 code for myoclonus?

The ICD-10-CM code for myoclonus is G25.3 (sometimes written as G253). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G25.3 (Other extrapyramidal and movement disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report myoclonus on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G25.3 group to?

When myoclonus is the principal diagnosis on an inpatient stay, it groups to MS-DRG 91, 92, 93, with relative weights from 0.7783 to 1.7050 depending on complications. Higher weights mean higher Medicare reimbursement.

Can G25.3 be reported with G51.4?

Not as a rule. The Excludes1 note on G25.3 lists "facial myokymia (G51.4)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does G25.3 need an additional code?

When the condition applies, yes. The Use Additional Code note reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after G25.3.