2026 ICD-10-CM Diagnosis Code E16.A2Hypoglycemia level 2

ICD-10-CM Codes›E00–E89›E15-E16›E16

ICD-10-CM E16.A2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E16.A2 is a billable ICD-10-CM diagnosis code for hypoglycemia level 2. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified endocrine disorders.

Code Identity

ICD-10-CM Code
E16.A2
Billable Status
Yes — Valid for Submission
Code Describes
Hypoglycemia level 2
Short Description
Hypoglycemia level 2
Same as the full description in the CMS dataset.
Parent Code
E16.A
Hypoglycemia level

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE15-E16Other disorders of glucose regulation and pancreatic internal secretion
CategoryE16Other disorders of pancreatic internal secretion
This CodeE16.A2Hypoglycemia level 2

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Decreased blood glucose level 2

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Decrease(d)
      • blood
        • glucose
          • level 2
    • Hypoglycemia(spontaneous)
      • level
        • 2

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END015
Other specified and unspecified endocrine disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Code History & ChangesHistory

Replacement E16.A2 replaces the following previously assigned code(s):

  • E16.2 - Hypoglycemia, unspecified
FY 2025AddedAdded to the ICD-10-CM code setEffective October 1, 2024.
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E16.A2Overview

Is E16.A2 (Hypoglycemia level) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hypoglycemia level 2 on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E16.A2 group to?

When hypoglycemia level 2 is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.