2026 ICD-10-CM Diagnosis Code E11.649Type 2 diabetes mellitus with hypoglycemia without coma

ICD-10-CM Codes›E00–E89›E08-E13›E11

ICD-10-CM E11.649
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E11.649 is a billable ICD-10-CM diagnosis code for type 2 diabetes mellitus with hypoglycemia without coma. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 637 through 639. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Diabetes mellitus with complication; and Diabetes mellitus, Type 2.

This medical diagnosis code is frequently used in Family Practice medical specialties to designate conditions such diabetes mellitus with complications type 2.

Code Identity

ICD-10-CM Code
E11.649
Billable Status
Yes — Valid for Submission
Code Describes
Type 2 diabetes mellitus with hypoglycemia without coma
Short Description
Type 2 diabetes mellitus with hypoglycemia without coma
Same as the full description in the CMS dataset.
Parent Code
E11.64
Type 2 diabetes mellitus with hypoglycemia

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE08-E13Diabetes mellitus
CategoryE11Type 2 diabetes mellitus
This CodeE11.649Type 2 diabetes mellitus with hypoglycemia without coma

Quality Payment Program MeasuresBilling

Medicare quality measures that can apply when E11.649 is part of the patient record.

Diabetes: Hemoglobin A1c (HbA1c) Poor Control (>9%)

High Priority: YES

Measure Type: Intermediateoutcome

Submission Methods: Claims, Electronic Health Record, Cms Web Interface, Registry

Description: Percentage of patients 18-75 years of age with diabetes who had hemoglobin A1c > 9.0% during the measurement period.

View Measure

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Hypoglycemia due to diabetes mellitus
  • Hypoglycemia due to type 2 diabetes mellitus
  • Hypoglycemia unawareness due to type 2 diabetes mellitus
  • Hypoglycemic attack requiring 3rd party assistance
  • Hypoglycemic event due to diabetes
  • Insulin reactive hypoglycemia due to type 2 diabetes mellitus
  • Last hypoglycemia attack
  • Loss of hypoglycemic warning due to diabetes mellitus
  • Reactive hypoglycemia

Coding GuidelinesGuidance

The diabetes mellitus codes are combination codes that include the type of diabetes mellitus, the body system affected, and the complications affecting that body system. As many codes within a particular category as are necessary to describe all of the complications of the disease may be used. They should be sequenced based on the reason for a particular encounter. Assign as many codes from categories E08 - E13 as needed to identify all of the associated conditions that the patient has.

If the type of diabetes mellitus is not documented in the medical record the default is E11.-, Type 2 diabetes mellitus.

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Diabetes, diabetic(mellitus) (sugar)
      • with
        • hypoglycemia
    • Diabetes, diabetic(mellitus) (sugar)
      • type 2
        • with
          • hypoglycemia

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END003
Diabetes mellitus with complication
Default principal diagnosis: inpatient Yes · outpatient Yes
CCSR END005
Diabetes mellitus, Type 2
Default principal diagnosis: inpatient No · outpatient No

Patient EducationClinical

Diabetes Complications

If you have diabetes, your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. A hormone called insulin helps the glucose get into your cells to give them energy.

The full article covers:

  • What is diabetes?
  • What health problems can diabetes cause?
  • What other problems can people with diabetes have?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E11.649 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
250.80 DMII oth nt st uncntrld
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E11.649Overview

Is E11.649 (Type 2 diabetes mellitus with hypoglycemia) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report type 2 diabetes mellitus with hypoglycemia without coma on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E11.649 group to?

When type 2 diabetes mellitus with hypoglycemia without coma is the principal diagnosis on an inpatient stay, it groups to MS-DRG 637, 638, 639, with relative weights from 0.6212 to 1.4367 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E11.649?

Under the General Equivalence Mappings, type 2 diabetes mellitus with hypoglycemia without coma converts to ICD-9-CM 250.80 (DMII oth nt st uncntrld). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.