2022 ICD-10-CM Code E11.35

Type 2 diabetes mellitus with proliferative diabetic retinopathy

Version 2021

Not Valid for Submission

ICD-10:E11.35
Short Description:Type 2 diabetes w proliferative diabetic retinopathy
Long Description:Type 2 diabetes mellitus with proliferative diabetic retinopathy

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Diabetes mellitus (E08-E13)
      • Type 2 diabetes mellitus (E11)

E11.35 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of type 2 diabetes mellitus with proliferative diabetic retinopathy. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Coding Guidelines

The diabetes mellitus codes are combination codes that include the type of diabetes mellitus, the body system affected, and the complications affecting that body system. As many codes within a particular category as are necessary to describe all of the complications of the disease may be used. They should be sequenced based on the reason for a particular encounter. Assign as many codes from categories E08 - E13 as needed to identify all of the associated conditions that the patient has.

If the type of diabetes mellitus is not documented in the medical record the default is E11.-, Type 2 diabetes mellitus.

Specific Coding for Type 2 diabetes w proliferative diabetic retinopathy

Non-specific codes like E11.35 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for type 2 diabetes w proliferative diabetic retinopathy:

  • NON-BILLABLE CODE - E11.351 for Type 2 diabetes mellitus with proliferative diabetic retinopathy with macular edema
  • BILLABLE CODE - Use E11.3511 for right eye
  • BILLABLE CODE - Use E11.3512 for left eye
  • BILLABLE CODE - Use E11.3513 for bilateral
  • BILLABLE CODE - Use E11.3519 for unspecified eye
  • NON-BILLABLE CODE - E11.352 for Type 2 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment involving the macula
  • BILLABLE CODE - Use E11.3521 for right eye
  • BILLABLE CODE - Use E11.3522 for left eye
  • BILLABLE CODE - Use E11.3523 for bilateral
  • BILLABLE CODE - Use E11.3529 for unspecified eye
  • NON-BILLABLE CODE - E11.353 for Type 2 diabetes mellitus with proliferative diabetic retinopathy with traction retinal detachment not involving the macula
  • BILLABLE CODE - Use E11.3531 for right eye
  • BILLABLE CODE - Use E11.3532 for left eye
  • BILLABLE CODE - Use E11.3533 for bilateral
  • BILLABLE CODE - Use E11.3539 for unspecified eye
  • NON-BILLABLE CODE - E11.354 for Type 2 diabetes mellitus with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment
  • BILLABLE CODE - Use E11.3541 for right eye
  • BILLABLE CODE - Use E11.3542 for left eye
  • BILLABLE CODE - Use E11.3543 for bilateral
  • BILLABLE CODE - Use E11.3549 for unspecified eye
  • NON-BILLABLE CODE - E11.355 for Type 2 diabetes mellitus with stable proliferative diabetic retinopathy
  • BILLABLE CODE - Use E11.3551 for right eye
  • BILLABLE CODE - Use E11.3552 for left eye
  • BILLABLE CODE - Use E11.3553 for bilateral
  • BILLABLE CODE - Use E11.3559 for unspecified eye
  • NON-BILLABLE CODE - E11.359 for Type 2 diabetes mellitus with proliferative diabetic retinopathy without macular edema
  • BILLABLE CODE - Use E11.3591 for right eye
  • BILLABLE CODE - Use E11.3592 for left eye
  • BILLABLE CODE - Use E11.3593 for bilateral
  • BILLABLE CODE - Use E11.3599 for unspecified eye

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E11.35:


7th Character Note

7th Character Note
Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.

7th Character

7th Character
Indicates that a seventh character is to be assigned to codes in a subcategory.

Information for Patients


Diabetes Type 2

What is type 2 diabetes?

Type 2 diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose is your main source of energy. It comes from the foods you eat. A hormone called insulin helps the glucose get into your cells to give them energy. If you have diabetes, your body doesn't make enough insulin or doesn't use insulin well. The glucose then stays in your blood and not enough goes into your cells.

Over time, having too much glucose in your blood can cause health problems. But you can take steps to manage your diabetes and try to prevent these health problems.

What causes type 2 diabetes?

Type 2 diabetes may be caused by a combination of factors:

Type 2 diabetes usually starts with insulin resistance. This is a condition in which your cells don't respond normally to insulin. As a result, your body needs more insulin to help the glucose enter your cells. At first, your body makes more insulin to try to get cells to respond. But over time, your body can't make enough insulin, and your blood glucose levels rise.

Who is at risk for type 2 diabetes?

You are at higher risk of developing type 2 diabetes if you

What are the symptoms of type 2 diabetes?

Many people with type 2 diabetes have no symptoms at all. If you do have them, the symptoms develop slowly over several years. They might be so mild that you do not notice them. The symptoms can include

How is type 2 diabetes diagnosed?

Your health care provider will use blood tests to diagnose type 2 diabetes. The blood tests include

What are the treatments for type 2 diabetes?

Treatment for type 2 diabetes involves managing your blood sugar levels. Many people are able to do this by living a healthy lifestyle. Some people may also need to take medicine.

Can type 2 diabetes be prevented?

You can take steps to help prevent or delay type 2 diabetes by losing weight if you are overweight, eating fewer calories, and being more physically active. If you have a condition which raises your risk for type 2 diabetes, managing that condition may lower your risk of getting type 2 diabetes.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


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Diabetic Eye Problems

If you have diabetes, your blood glucose, or blood sugar, levels are too high. Over time, this can damage your eyes. The most common problem is diabetic retinopathy. It is a leading cause of blindness in American adults.

Your retina is the light-sensitive tissue at the back of your eye. You need a healthy retina to see clearly. Diabetic retinopathy damages the tiny blood vessels inside your retina.

You may not notice it at first. Symptoms can include

Treatment often includes laser treatment or surgery, with follow-up care.

Two other eye problems can happen to people with diabetes. A cataract is a cloud over the lens of your eye. Surgery helps you see clearly again. Glaucoma happens when pressure builds up in the eye, damaging the main nerve. Eye drops or surgery can help.

If you have diabetes, you should have a complete eye exam every year. Finding and treating problems early may save your vision.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


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Type 2 diabetes

Type 2 diabetes is a disorder characterized by abnormally high blood sugar levels. In this form of diabetes, the body stops using and making insulin properly. Insulin is a hormone produced in the pancreas that helps regulate blood sugar levels. Specifically, insulin controls how much glucose (a type of sugar) is passed from the blood into cells, where it is used as an energy source. When blood sugar levels are high (such as after a meal), the pancreas releases insulin to move the excess glucose into cells, which reduces the amount of glucose in the blood.

Most people who develop type 2 diabetes first have insulin resistance, a condition in which the body's cells use insulin less efficiently than normal. As insulin resistance develops, more and more insulin is needed to keep blood sugar levels in the normal range. To keep up with the increasing need, insulin-producing cells in the pancreas (called beta cells) make larger amounts of insulin. Over time, the beta cells become less able to respond to blood sugar changes, leading to an insulin shortage that prevents the body from reducing blood sugar levels effectively. Most people have some insulin resistance as they age, but inadequate exercise and excessive weight gain make it worse, greatly increasing the likelihood of developing type 2 diabetes.

Type 2 diabetes can occur at any age, but it most commonly begins in middle age or later. Signs and symptoms develop slowly over years. They include frequent urination (polyuria), excessive thirst (polydipsia), fatigue, blurred vision, tingling or loss of feeling in the hands and feet (diabetic neuropathy), sores that do not heal well, and weight loss. If blood sugar levels are not controlled through medication or diet, type 2 diabetes can cause long-lasting (chronic) health problems including heart disease and stroke; nerve damage; and damage to the kidneys, eyes, and other parts of the body.


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Diabetic Eye Disease Learn about diabetes and eye disease; symptoms, warning signs, and treatments; and how you can prevent eye disease—or keep it from getting worse.
[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)