2027 ICD-10-CM Diagnosis Code E01.1Iodine-deficiency related multinodular (endemic) goiter

ICD-10-CM Codes›E00–E89›E00-E07›E01

ICD-10-CM E01.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E01.1 is a billable ICD-10-CM diagnosis code for iodine-deficiency related multinodular (endemic) goiter. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. Coders also document this condition as endemic goiter. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Thyroid disorders.

E01.1 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 44 for payment year 2027.

Code Identity

ICD-10-CM Code
E01.1
Billable Status
Yes — Valid for Submission
Code Describes
Iodine-deficiency related multinodular (endemic) goiter
Short Description
Iodine-deficiency related multinodular (endemic) goiter
Same as the full description in the CMS dataset.
Parent Code
E01
Iodine-deficiency related thyroid disorders and allied conditions

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE00-E07Disorders of thyroid gland
CategoryE01Iodine-deficiency related thyroid disorders and allied conditions
This CodeE01.1Iodine-deficiency related multinodular (endemic) goiter

Medicare Risk Adjustment (HCC)Billing

E01.1 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
no payment category in the model that pays 100% of MA risk scores
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Part D (RxHCC)
RxHCC 44 — Thyroid Disorders
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Endemic goiter
  • Iodine-deficiency-related multinodular endemic goiter
  • Multinodular goiter
  • Thyroid follicular nodular disease

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E01.1: its own notes plus those printed at E01 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Iodine-deficiency related nodular goiter

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From E01 Iodine-deficiency related thyroid disorders and allied conditions applies to 4 codes
  • congenital iodine-deficiency syndrome (E00.-)
  • subclinical iodine-deficiency hypothyroidism (E02)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E01.1, its category, or a range that includes it.

Applicable To 1

These notes mention E01.1.

  • Z83.4 Family history of other endocrine, nutritional and metabolic diseases
    Conditions classifiable to E00-E07, E15-E88 names E00-E07, which includes this code

Excludes1 3

These codes carry an Excludes1 note naming E01.1: they are not reported together with it, unless the two conditions are unrelated.

  • E03 Other hypothyroidism
    iodine-deficiency related hypothyroidism (E00-E02) names E00-E02, which includes this code
  • E04 Other nontoxic goiter
    iodine-deficiency related goiter (E00-E02) names E00-E02, which includes this code
  • E61 Deficiency of other nutrient elements
    iodine deficiency related thyroid disorders (E00-E02) names E00-E02, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming E01.1: its condition is not part of those codes, and both may be reported when the patient has both.

  • Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
    iodine-deficiency-related hypothyroidism (E00-E02) names E00-E02, which includes this code

Code First 5

These codes say to code first a condition named in the note, and E01.1 is one of the conditions named.

  • D63.8 Anemia in other chronic diseases classified elsewhere
    hypothyroidism (E00.0-E03.9) names E00.0-E03.9, which includes this code
  • F02 Dementia in other diseases classified elsewhere
    hypothyroidism, acquired (E00-E03.-) names E00-E03, which includes this code
  • G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
    cerebral degeneration (due to) hypothyroidism (E00.0-E03.9) names E00.0-E03.9, which includes this code
  • G63 Polyneuropathy in diseases classified elsewhere
    endocrine disease, except diabetes (E00-E07, E15-E16, E20-E34) names E00-E07, which includes this code
  • M14.8 Arthropathies in other specified diseases classified elsewhere
    hypothyroidism (E00-E03) names E00-E03, which includes this code

Code Also 1

These codes say E01.1 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • I27.29 Other secondary pulmonary hypertension
    hypothyroidism (E00-E03) names E00-E03, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END001
Thyroid disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Multinodular Endemic Goiter

    a multinodular goiter caused by inadequate iodine intake.

Patient EducationClinical

Thyroid Diseases

Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E01.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
241.1 Nontox multinodul goiter
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E01.1Overview

What is the ICD-10 code for iodine-deficiency related multinodular (endemic) goiter?

The ICD-10-CM code for iodine-deficiency related multinodular (endemic) goiter is E01.1 (sometimes written as E011). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is E01.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report iodine-deficiency related multinodular (endemic) goiter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does E01.1 group to?

When iodine-deficiency related multinodular (endemic) goiter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.

Can E01.1 be reported with a code from E00?

Not as a rule. The Excludes1 note at E01, which applies to E01.1, lists "congenital iodine-deficiency syndrome (E00.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of E01.1?

Under the General Equivalence Mappings, iodine-deficiency related multinodular (endemic) goiter converts to ICD-9-CM 241.1 (nontox multinodul goiter). The mapping is approximate, so confirm the match fits the documentation.

Does E01.1 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage: E01.1 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 44 (Thyroid Disorders).