2026 ICD-10-CM Diagnosis Code E01.1Iodine-deficiency related multinodular (endemic) goiter

ICD-10-CM Codes›E00–E89›E00-E07›E01

ICD-10-CM E01.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E01.1 is a billable ICD-10-CM diagnosis code for iodine-deficiency related multinodular (endemic) goiter. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 643 through 645. Coders also document this condition as endemic goiter. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Thyroid disorders.

Code Identity

ICD-10-CM Code
E01.1
Billable Status
Yes — Valid for Submission
Code Describes
Iodine-deficiency related multinodular (endemic) goiter
Short Description
Iodine-deficiency related multinodular (endemic) goiter
Same as the full description in the CMS dataset.
Parent Code
E01
Iodine-deficiency related thyroid disorders and allied conditions

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE00-E07Disorders of thyroid gland
CategoryE01Iodine-deficiency related thyroid disorders and allied conditions
This CodeE01.1Iodine-deficiency related multinodular (endemic) goiter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Endemic goiter
  • Iodine-deficiency-related multinodular endemic goiter
  • Multinodular goiter

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Iodine-deficiency related nodular goiter

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Goiter(plunging) (substernal)
      • cystic
        • due to iodine-deficiency
    • Goiter(plunging) (substernal)
      • endemic (iodine-deficiency)
        • multinodular
    • Goiter(plunging) (substernal)
      • iodine-deficiency (endemic)
        • multinodular
    • Goiter(plunging) (substernal)
      • iodine-deficiency (endemic)
        • nodular
    • Goiter(plunging) (substernal)
      • nodular (nontoxic) (due to)
        • endemic
    • Goiter(plunging) (substernal)
      • nodular (nontoxic) (due to)
        • iodine-deficiency
    • Struma
      • nodosa (simplex)
        • endemic
          • multinodular
    • Struma
      • nodosa (simplex)
        • multinodular
          • iodine-deficiency related

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END001
Thyroid disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Multinodular Goiter

    nodular goiter characterized by more than one discrete tissue mass.

  • Non-Toxic Multinodular Goiter|Nontoxic multinodular goiter

    a multinodular goiter that is not associated with changes in thyroid function or malignancy.

  • Thyrotoxicosis with Toxic Multinodular Goiter with Thyrotoxic Crisis|Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis

    evidence of thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis.

  • Thyrotoxicosis with Toxic Multinodular Goiter without Thyrotoxic Crisis|Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis

    evidence of thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis.

Patient EducationClinical

Thyroid Diseases

Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E01.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
241.1 Nontox multinodul goiter
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E01.1Overview

Is E01.1 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report iodine-deficiency related multinodular (endemic) goiter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does E01.1 group to?

When iodine-deficiency related multinodular (endemic) goiter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 643, 644, 645, with relative weights from 0.7683 to 1.6461 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of E01.1?

Under the General Equivalence Mappings, iodine-deficiency related multinodular (endemic) goiter converts to ICD-9-CM 241.1 (nontox multinodul goiter). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.