2027 ICD-10-CM Diagnosis Code D78.21Postprocedural hemorrhage of the spleen following a procedure on the spleen

ICD-10-CM Codes›D50–D89›D78›D78

ICD-10-CM D78.21
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

D78.21 is a billable ICD-10-CM diagnosis code for postprocedural hemorrhage of the spleen following a procedure on the spleen. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 919 through 921. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 78 closely related codes. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Postprocedural or postoperative complications of the spleen.

Code Identity

ICD-10-CM Code
D78.21
Billable Status
Yes — Valid for Submission
Code Describes
Postprocedural hemorrhage of the spleen following a procedure on the spleen
Short Description
Postprocedural hemorrhage of the spleen fol proc on spleen
Parent Code
D78.2
Postprocedural hemorrhage of the spleen following a procedure

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD78Intraoperative and postprocedural complications of the spleen
CategoryD78Intraoperative and postprocedural complications of the spleen
This CodeD78.21Postprocedural hemorrhage of the spleen following a procedure on the spleen

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to D78.21: its own notes plus those printed at Chapter 3. A note printed at a category, block or chapter applies to every code under it.

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 3 (D50-D89) Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism applies to 324 codes
  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name D78.21, its category, or a range that includes it.

Excludes2 2

These codes carry an Excludes2 note naming D78.21: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block T80-T88 Complications of surgical and medical care, not elsewhere classified
    intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-) names D78.-, which includes this code
  • T81 Complications of procedures, not elsewhere classified
    intraoperative and postprocedural complications of specific body system (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95, K91.-, L76.-, M96.-, N99.-) names D78.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD009
Postprocedural or postoperative complications of the spleen
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Spleen Diseases

Your spleen is an organ above your stomach and under your ribs on your left side. It is about as big as your fist. The spleen is part of your lymphatic system, which fights infection and keeps your body fluids in balance. It contains white blood cells that fight germs.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D78.21 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
998.11 Hemorrhage complic proc
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About D78.21Overview

Is D78.21 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report postprocedural hemorrhage of the spleen following a procedure on the spleen on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does D78.21 group to?

When postprocedural hemorrhage of the spleen following a procedure on the spleen is the principal diagnosis on an inpatient stay, it groups to MS-DRG 920, 919, 921, with relative weights from 0.6719 to 1.7624 depending on complications. Higher weights mean higher Medicare reimbursement.

Is D78.21 a CC or MCC?

CMS lists D78.21 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 78 closely related codes in its exclusion list.

What is the ICD-9 equivalent of D78.21?

Under the General Equivalence Mappings, postprocedural hemorrhage of the spleen following a procedure on the spleen converts to ICD-9-CM 998.11 (hemorrhage complic proc). The mapping is approximate, so confirm the match fits the documentation.