2026 ICD-10-CM Diagnosis Code D43.2Neoplasm of uncertain behavior of brain, unspecified

ICD-10-CM CodesC00–D49D37-D48D43

ICD-10-CM D43.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D43.2 is a billable ICD-10-CM diagnosis code for neoplasm of uncertain behavior of brain, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D43.2
Billable Status
Yes — Valid for Submission
Code Describes
Neoplasm of uncertain behavior of brain, unspecified
Short Description
Neoplasm of uncertain behavior of brain, unspecified
Same as the full description in the CMS dataset.
Parent Code
Neoplasm of uncertain behavior of brain and central nervous system

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD43Neoplasm of uncertain behavior of brain and central nervous system
This CodeD43.2Neoplasm of uncertain behavior of brain, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Angiocentric glioma of brain
  • Angiocentric glioma of central nervous system
  • Central neurocytoma of brain
  • Embryonal tumor of brain
  • Low grade glioma of cerebrum
  • Myxopapillary ependymoma of brain
  • Neoplasm of uncertain behavior of brain
  • Neoplasm of uncertain behavior of brain and spinal cord
  • Papillary glioneuronal tumor of brain
  • Rosette-forming glioneuronal neoplasm
  • Subependymal giant cell astrocytoma
  • Subependymoma of brain

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Astrocytoma(cystic)
      • subependymal
    • Astrocytoma(cystic)
      • subependymal
        • giant cell
          • unspecified site
    • Astrocytoma(cystic)
      • subependymal
        • unspecified site
    • Ependymoma(epithelial) (malignant)
      • myxopapillary
    • Ependymoma(epithelial) (malignant)
      • myxopapillary
        • unspecified site
    • Ependymoma(epithelial) (malignant)
      • papillary
    • Ependymoma(epithelial) (malignant)
      • papillary
        • unspecified site
    • Glioma(malignant)
      • subependymal
    • Glioma(malignant)
      • subependymal
        • unspecified site
    • Subependymoma
      • unspecified site

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
brain NECC71.9C79.31D33.2D43.2D49.6
brain NEC corpus callosumC71.8C79.31D33.2D43.2D49.6
brain NEC tapetumC71.8C79.31D33.2D43.2D49.6
corpus callosum, brainC71.0C79.31D33.2D43.2D49.6
cranial (fossa, any)C71.9C79.31D33.2D43.2D49.6
fossa (of)C71.9C79.31D33.2D43.2D49.6
fossa (of) anterior (cranial)C71.9C79.31D33.2D43.2D49.6
fossa (of) cranialC71.9C79.31D33.2D43.2D49.6
fossa (of) middle (cranial)C71.9C79.31D33.2D43.2D49.6
fossa (of) posterior (cranial)C71.9C79.31D33.2D43.2D49.6
intracranial NECC71.9C79.31D33.2D43.2D49.6
motor tract brainC71.9C79.31D33.2D43.2D49.6
posterior fossa (cranial)C71.9C79.31D33.2D43.2D49.6
suprasellar (region)C71.9C79.31D33.2D43.2D49.6
tapetum, brainC71.8C79.31D33.2D43.2D49.6

Patient EducationClinical

Brain Diseases

Your brain is the control center of your body. It controls your thoughts, memory, speech, and movement. It regulates the function of many organs. It's part of your nervous system, which also includes your spinal cord and peripheral nerves. The nervous system sends signals between your brain and the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D43.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
237.5 Unc beh neo brain/spinal
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D43.2Overview

Is D43.2 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report neoplasm of uncertain behavior of brain, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of D43.2?

Under the General Equivalence Mappings, neoplasm of uncertain behavior of brain, unspecified converts to ICD-9-CM 237.5 (unc beh neo brain/spinal). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.