2026 ICD-10-CM Diagnosis Code D21.5Benign neoplasm of connective and other soft tissue of pelvis

ICD-10-CM CodesC00–D49D10-D36D21

ICD-10-CM D21.5
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D21.5 is a billable ICD-10-CM diagnosis code for benign neoplasm of connective and other soft tissue of pelvis. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.

Code Identity

ICD-10-CM Code
D21.5
Billable Status
Yes — Valid for Submission
Code Describes
Benign neoplasm of connective and other soft tissue of pelvis
Short Description
Benign neoplasm of connective and oth soft tissue of pelvis
Parent Code
Other benign neoplasms of connective and other soft tissue

Code Classification

ChapterC00–D49Neoplasms
SectionD10-D36Benign neoplasms, except benign neuroendocrine tumors
CategoryD21Other benign neoplasms of connective and other soft tissue
This CodeD21.5Benign neoplasm of connective and other soft tissue of pelvis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Benign neoplasm of blood vessel of buttock
  • Benign neoplasm of blood vessel of inguinal region
  • Benign neoplasm of blood vessel of lower limb
  • Benign neoplasm of blood vessel of pelvis
  • Benign neoplasm of blood vessel of perineum
  • Benign neoplasm of coccygeal body
  • Benign neoplasm of inguinal region
  • Benign neoplasm of muscle of buttock
  • Benign neoplasm of muscle of hip
  • Benign neoplasm of muscle of inguinal region
  • Benign neoplasm of muscle of lower limb
  • Benign neoplasm of muscle of pelvis
  • Benign neoplasm of muscle of perineum
  • Benign neoplasm of muscle of trunk
  • Benign neoplasm of paraganglion
  • Benign neoplasm of skin of buttock
  • Benign neoplasm of soft tissues of buttock
  • Benign neoplasm of soft tissues of inguinal region
  • Benign neoplasm of soft tissues of pelvis
  • Benign neoplasm of soft tissues of perineum
  • Neoplasm of blood vessel of buttock
  • Neoplasm of blood vessel of inguinal region
  • Neoplasm of blood vessel of pelvis
  • Neoplasm of blood vessel of perineum
  • Neoplasm of coccygeal body
  • Neoplasm of muscle of buttock
  • Neoplasm of muscle of hip
  • Neoplasm of muscle of inguinal region
  • Neoplasm of muscle of pelvis
  • Neoplasm of muscle of perineum
  • Neoplasm of skin of buttock
  • Neoplasm of soft tissues of inguinal region

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • benign neoplasm of any uterine ligament D28.2
  • uterine leiomyoma D25

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO073
Benign neoplasms
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
coccygealC49.5C79.89D21.5D48.1D49.2
coccygeal body or glomusC49.5C79.89D21.5D48.1D49.2
connective tissue NEC buttockC49.5C79.89D21.5D48.1D49.2
connective tissue NEC extrarectalC49.5C79.89D21.5D48.1D49.2
connective tissue NEC gluteal regionC49.5C79.89D21.5D48.1D49.2
connective tissue NEC groinC49.5C79.89D21.5D48.1D49.2
connective tissue NEC iliopsoas muscleC49.5C79.89D21.5D48.1D49.2
connective tissue NEC inguinal (canal) (region)C49.5C79.89D21.5D48.1D49.2
connective tissue NEC ischiorectal fossaC49.5C79.89D21.5D48.1D49.2
connective tissue NEC natesC49.5C79.89D21.5D48.1D49.2
connective tissue NEC pararectalC49.5C79.89D21.5D48.1D49.2
connective tissue NEC para-urethralC49.5C79.89D21.5D48.1D49.2
connective tissue NEC paravaginalC49.5C79.89D21.5D48.1D49.2
connective tissue NEC pelvis (floor)C49.5C79.89D21.5D48.1D49.2
connective tissue NEC perineumC49.5C79.89D21.5D48.1D49.2
connective tissue NEC perirectal (tissue)C49.5C79.89D21.5D48.1D49.2
connective tissue NEC periurethral (tissue)C49.5C79.89D21.5D48.1D49.2
connective tissue NEC presacralC49.5C79.89D21.5D48.1D49.2
connective tissue NEC rectovaginal septum or wallC49.5C79.89D21.5D48.1D49.2
connective tissue NEC rectovesicalC49.5C79.89D21.5D48.1D49.2
connective tissue NEC sacrococcygeal regionC49.5C79.89D21.5D48.1D49.2
connective tissue NEC vesicorectalC49.5C79.89D21.5D48.1D49.2
glomusC49.5C79.89D21.5D48.1D49.2
glomus coccygealC49.5C79.89D21.5D48.1D49.2

Patient EducationClinical

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D21.5 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
215.6 Ben neo soft tis pelvis
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D21.5Overview

Is D21.5 (Other benign neoplasms of connective and other soft tissue) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of connective and other soft tissue of pelvis on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D21.5 group to?

When benign neoplasm of connective and other soft tissue of pelvis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D21.5?

Under the General Equivalence Mappings, benign neoplasm of connective and other soft tissue of pelvis converts to ICD-9-CM 215.6 (ben neo soft tis pelvis). The mapping is a direct match.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.