2027 ICD-10-CM Diagnosis Code D21.3Benign neoplasm of connective and other soft tissue of thorax
ICD-10-CM Codes›C00–D49›D10-D36›D21
- Billable — Valid for Submission
- Not Chronic
D21.3 is a billable ICD-10-CM diagnosis code for benign neoplasm of connective and other soft tissue of thorax. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 564 through 566. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Benign neoplasm of blood vessel of axilla
- Benign neoplasm of blood vessel of shoulder
- Benign neoplasm of blood vessel of thorax
- Benign neoplasm of blood vessel of upper limb
- Benign neoplasm of diaphragm
- Benign neoplasm of great vessels
- Benign neoplasm of muscle of abdomen
- Benign neoplasm of muscle of thorax
- Benign neoplasm of muscle of trunk
- Benign neoplasm of soft tissue of back of trunk
- Benign neoplasm of soft tissues of axilla
- Benign neoplasm of soft tissues of thorax
- Benign neoplasm soft tissue of thoracic spine
- Fibroma of chest wall
- Neoplasm of blood vessel of axilla
- Neoplasm of blood vessel of shoulder
- Neoplasm of blood vessel of thorax
- Neoplasm of diaphragm
- Neoplasm of great vessels
- Neoplasm of muscle of abdomen
- Neoplasm of muscle of thorax
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to D21.3: its own notes plus those printed at D21 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- benign neoplasm of blood vessel
- benign neoplasm of bursa
- benign neoplasm of cartilage
- benign neoplasm of fascia
- benign neoplasm of fat
- benign neoplasm of ligament, except uterine
- benign neoplasm of lymphatic channel
- benign neoplasm of muscle
- benign neoplasm of synovia
- benign neoplasm of tendon (sheath)
- benign stromal tumors
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Benign neoplasm of axilla
- Benign neoplasm of diaphragm
- Benign neoplasm of great vessels
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- benign neoplasm of articular cartilage (D16.-)
- benign neoplasm of cartilage of larynx (D14.1)
- benign neoplasm of cartilage of nose (D14.0)
- benign neoplasm of connective tissue of breast (D24.-)
- benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
- benign neoplasm of peritoneum (D20.1)
- benign neoplasm of retroperitoneum (D20.0)
- benign neoplasm of uterine ligament, any (D28.2)
- benign neoplasm of vascular tissue (D18.-)
- hemangioma (D18.0-)
- lipomatous neoplasm (D17.-)
- lymphangioma (D18.1)
- uterine leiomyoma (D25.-)
Notes
General instructions on how these codes are used.
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name D21.3, its category, or a range that includes it.
Excludes1 2
These codes carry an Excludes1 note naming D21.3: they are not reported together with it, unless the two conditions are unrelated.
Code First 1
These codes say to code first a condition named in the note, and D21.3 is one of the conditions named.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| aorta (thoracic) | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › axilla | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › chest (wall) | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › diaphragm | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › great vessels NEC | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › infraclavicular region | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › intrathoracic | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › scapular region | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › thoracic (duct) (wall) | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| connective tissue NEC › thorax | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| diaphragm | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| great vessels NEC | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| thorax, thoracic (cavity) (organs NEC) › duct | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
| vena cava (abdominal) (inferior) › superior | C49.3 | C79.89 | – | D21.3 | D48.1 | D49.2 |
Patient EducationClinical
Benign Tumors
Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D21.3 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D21.3Overview
What is the ICD-10 code for benign neoplasm of connective and other soft tissue of thorax?
The ICD-10-CM code for benign neoplasm of connective and other soft tissue of thorax is D21.3 (sometimes written as D213). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is D21.3 (Other benign neoplasms of connective and other soft tissue) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of connective and other soft tissue of thorax on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does D21.3 group to?
When benign neoplasm of connective and other soft tissue of thorax is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 566, 565, with relative weights from 0.7374 to 1.4909 depending on complications. Higher weights mean higher Medicare reimbursement.
Can D21.3 be reported with D15.1?
Not as a rule. The Excludes1 note on D21.3 lists "benign neoplasm of heart (D15.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What is the ICD-9 equivalent of D21.3?
Under the General Equivalence Mappings, benign neoplasm of connective and other soft tissue of thorax converts to ICD-9-CM 215.4 (ben neo soft tis thorax). The mapping is a direct match.
