2026 ICD-10-CM Diagnosis Code D21.0Benign neoplasm of connective and other soft tissue of head, face and neck
ICD-10-CM Codes›C00–D49›D10-D36›D21
- Billable — Valid for Submission
- Not Chronic
D21.0 is a billable ICD-10-CM diagnosis code for benign neoplasm of connective and other soft tissue of head, face and neck. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Benign neoplasms.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Apocrine hidrocystoma
- Apocrine hidrocystoma of eyelid
- Benign neoplasm of blood vessel of face
- Benign neoplasm of blood vessel of head
- Benign neoplasm of blood vessel of neck
- Benign neoplasm of canthus
- Benign neoplasm of connective tissue of head and/or neck
- Benign neoplasm of ear
- Benign neoplasm of eyelid
- Benign neoplasm of lacrimal caruncle
- Benign neoplasm of muscle of face
- Benign neoplasm of muscle of head
- Benign neoplasm of muscle of neck
- Benign neoplasm of soft tissue of head and/or neck
- Benign neoplasm of soft tissues of face
- Benign neoplasm of soft tissues of head
- Benign neoplasm of soft tissues of neck
- Benign neoplasm of sweat gland
- Benign neoplasm soft tissue of cervical spine
- Cervicofacial fibrochondroma
- Eccrine hidrocystoma
- Fibroma of scalp
- Lacrimal caruncle finding
- Lump in caruncle of eye
- Neoplasm of blood vessel of face
- Neoplasm of blood vessel of neck
- Neoplasm of muscle of face
- Neoplasm of muscle of head
- Neoplasm of muscle of neck
- Nuchal fibroma
- Subcutaneous mass of neck
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Benign neoplasm of connective tissue of ear
- Benign neoplasm of connective tissue of eyelid
Type 1 Excludes
- benign neoplasm of connective tissue of orbit D31.6
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of NeoplasmsClinical
Anatomical sites in the Table of Neoplasms that reference this code family.
| Site | Malig. Primary | Malig. Secondary | Ca in situ | Benign | Uncertain | Unspec. |
|---|---|---|---|---|---|---|
| carotid (artery) | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › auricular | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › ear (external) | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › eyelid | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| cartilage (articular) (joint) NEC [See Also: Neoplasm, bone] › pinna | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › auricle (ear) | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › cervical region | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › cheek | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › chin | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › ear (external) | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › eyelid | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › face | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › forehead | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › head | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › neck | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › pterygoid fossa | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › scalp | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › submental | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › supraclavicular region | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › temple | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| connective tissue NEC › temporal region | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| ear (external) [See Also: Neoplasm, skin, ear] › cartilage | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| eyelid (lower) (skin) (upper) › cartilage | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| fossa (of) › pterygoid | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
| pterygoid fossa | C49.0 | C79.89 | – | D21.0 | D48.1 | D49.2 |
Patient EducationClinical
Benign Tumors
Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert D21.0 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About D21.0Overview
Is D21.0 (Other benign neoplasms of connective and other soft tissue) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report benign neoplasm of connective and other soft tissue of head, face and neck on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does D21.0 group to?
When benign neoplasm of connective and other soft tissue of head, face and neck is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of D21.0?
Under the General Equivalence Mappings, benign neoplasm of connective and other soft tissue of head, face and neck converts to ICD-9-CM 215.0 (ben neo soft tissue head). The mapping is a direct match.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
