2026 ICD-10-CM Diagnosis Code C48.2Malignant neoplasm of peritoneum, unspecified

ICD-10-CM Codes›C00–D49›C45-C49›C48

ICD-10-CM C48.2
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C48.2 is a billable ICD-10-CM diagnosis code for malignant neoplasm of peritoneum, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 374 through 376. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Gastrointestinal cancers - peritoneum.

Code Identity

ICD-10-CM Code
C48.2
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of peritoneum, unspecified
Short Description
Malignant neoplasm of peritoneum, unspecified
Same as the full description in the CMS dataset.
Parent Code
C48
Malignant neoplasm of retroperitoneum and peritoneum

Code Classification

ChapterC00–D49Neoplasms
SectionC45-C49Malignant neoplasms of mesothelial and soft tissue
CategoryC48Malignant neoplasm of retroperitoneum and peritoneum
This CodeC48.2Malignant neoplasm of peritoneum, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Carcinoma of peritoneum
  • Clear cell adenocarcinoma of peritoneum
  • Extraovarian primary peritoneal carcinoma
  • Leiomyosarcoma of connective tissue
  • Liposarcoma of connective tissue
  • Local recurrence of malignant neoplasm of peritoneum
  • Malignant neoplasm of peritoneum
  • Primary adenocarcinoma of peritoneum
  • Primary clear cell adenocarcinoma of peritoneum
  • Primary giant cell sarcoma of peritoneum
  • Primary leiomyosarcoma of abdomen
  • Primary leiomyosarcoma of peritoneum
  • Primary liposarcoma of peritoneum
  • Primary liposarcoma of soft tissue of abdomen
  • Primary liposarcoma of soft tissue of trunk
  • Primary malignant neoplasm of peritoneum
  • Primary sarcoma of peritoneum
  • Primary sarcoma of soft tissues of abdomen
  • Sarcoma of peritoneum

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO020
Gastrointestinal cancers - peritoneum
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary		Malig.
Secondary		Ca
in situ		BenignUncertainUnspec.
cavity › peritonealC48.2C78.6–D20.1D48.4D49.0
peritoneum, peritoneal (cavity)C48.2C78.6–D20.1D48.4D49.0

Patient EducationClinical

Cancer

Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should.

The full article covers:

  • What is cancer?
  • What are the types of cancer?
  • How does cancer develop?
  • What are the symptoms of cancer?
  • How is cancer diagnosed?
  • What are the treatments for cancer?
  • Can cancer be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C48.2 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
158.9 Mal neo peritoneum NOS
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C48.2Overview

Is C48.2 (Malignant neoplasm of retroperitoneum and peritoneum) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of peritoneum, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C48.2 group to?

When malignant neoplasm of peritoneum, unspecified is the principal diagnosis on an inpatient stay, it groups to MS-DRG 374, 375, 376, with relative weights from 0.9243 to 2.1387 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C48.2?

Under the General Equivalence Mappings, malignant neoplasm of peritoneum, unspecified converts to ICD-9-CM 158.9 (mal neo peritoneum NOS). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.