2026 ICD-10-CM Diagnosis Code C46.1Kaposi's sarcoma of soft tissue

ICD-10-CM CodesC00–D49C45-C49C46

ICD-10-CM C46.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C46.1 is a billable ICD-10-CM diagnosis code for Kaposi's sarcoma of soft tissue. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 606 through 607, 974 through 976. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Sarcoma.

Code Identity

ICD-10-CM Code
C46.1
Billable Status
Yes — Valid for Submission
Code Describes
Kaposi's sarcoma of soft tissue
Short Description
Kaposi's sarcoma of soft tissue
Same as the full description in the CMS dataset.
Parent Code
Kaposi's sarcoma

Code Classification

ChapterC00–D49Neoplasms
SectionC45-C49Malignant neoplasms of mesothelial and soft tissue
CategoryC46Kaposi's sarcoma
This CodeC46.1Kaposi's sarcoma of soft tissue

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Kaposi's sarcoma of soft tissue

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Kaposi's sarcoma of blood vessel
  • Kaposi's sarcoma of connective tissue
  • Kaposi's sarcoma of fascia
  • Kaposi's sarcoma of ligament
  • Kaposi's sarcoma of lymphatic(s) NEC
  • Kaposi's sarcoma of muscle

Type 2 Excludes

  • Kaposi's sarcoma of lymph glands and nodes C46.3

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Kaposi's
      • sarcoma
        • connective tissue
    • Sarcoma(of)
      • Kaposi's
        • connective tissue

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO024
Sarcoma
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Kaposi Sarcoma

Kaposi sarcoma, sometimes called KS, is a type of cancer. It causes lesions (abnormal tissue) to grow in different parts of the body, including:

The full article covers:

  • What is Kaposi sarcoma?
  • What causes Kaposi sarcoma and who is more likely to develop it?
  • What are the symptoms of Kaposi sarcoma?
  • How is Kaposi sarcoma diagnosed?
  • What are the treatments for Kaposi sarcoma?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C46.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
176.1 Sft tisue - kpsi's srcma
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C46.1Overview

Is C46.1 (Kaposi's sarcoma) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report Kaposi's sarcoma of soft tissue on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C46.1 group to?

When Kaposi's sarcoma of soft tissue is the principal diagnosis on an inpatient stay, it groups to MS-DRG 606, 607, 974, 975, 976, with relative weights from 0.8945 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C46.1?

Under the General Equivalence Mappings, Kaposi's sarcoma of soft tissue converts to ICD-9-CM 176.1 (sft tisue - kpsi's srcma). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.