2026 ICD-10-CM Diagnosis Code A52.74Syphilis of liver and other viscera

ICD-10-CM Codes›A00–B99›A50-A64›A52

ICD-10-CM A52.74
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

A52.74 is a billable ICD-10-CM diagnosis code for syphilis of liver and other viscera. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 441 through 443. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified liver disease and Sexually transmitted infections (excluding HIV and hepatitis).

Code Identity

ICD-10-CM Code
A52.74
Billable Status
Yes — Valid for Submission
Code Describes
Syphilis of liver and other viscera
Short Description
Syphilis of liver and other viscera
Same as the full description in the CMS dataset.
Parent Code
A52.7
Other symptomatic late syphilis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA50-A64Infections with a predominantly sexual mode of transmission
CategoryA52Late syphilis
This CodeA52.74Syphilis of liver and other viscera

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bacterial hepatitis
  • Bacterial portal cirrhosis
  • Congenital hepatomegaly
  • Congenital syphilitic hepatomegaly
  • Hepatitis in late syphilis
  • Infectious cirrhosis
  • Syphilis of liver
  • Syphilitic cirrhosis
  • Syphilitic peritonitis
  • Syphilitic portal cirrhosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Late syphilitic peritonitis

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Ascites(abdominal)
      • syphilitic
    • Cirrhosis, cirrhotic(hepatic) (liver)
      • liver
        • syphilitic
    • Gumma(syphilitic)
      • liver
    • Hepar lobatum(syphilitic)
    • Hepatitis
      • syphilitic (late)
    • Pancreatitis(annular) (apoplectic) (calcareous) (edematous) (hemorrhagic) (malignant) (subacute) (suppurative)
      • syphilitic
    • Peritonitis(adhesive) (bacterial) (fibrinous) (hemorrhagic) (idiopathic) (localized) (perforative) (primary) (with adhesions) (with effusion)
      • syphilitic
    • Stricture
      • rectum (sphincter)
        • syphilitic
    • Syphilis, syphilitic(acquired)
      • anus (late)
    • Syphilis, syphilitic(acquired)
      • colon (late)
    • Syphilis, syphilitic(acquired)
      • gallbladder (late)
    • Syphilis, syphilitic(acquired)
      • gastric (polyposis) (late)
    • Syphilis, syphilitic(acquired)
      • hepatis
    • Syphilis, syphilitic(acquired)
      • intestine (late)
    • Syphilis, syphilitic(acquired)
      • liver
    • Syphilis, syphilitic(acquired)
      • pancreas (late)
    • Syphilis, syphilitic(acquired)
      • rectum (late)
    • Syphilis, syphilitic(acquired)
      • small intestine
    • Syphilis, syphilitic(acquired)
      • stomach
    • Syphilis, syphilitic(acquired)
      • ventriculi
    • Syphilis, syphilitic(acquired)
      • viscera (abdominal) (late)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient No · outpatient No
CCSR INF010
Sexually transmitted infections (excluding HIV and hepatitis)
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Syphilis

Syphilis is a sexually transmitted infection (STI) caused by bacteria. It infects the genital area, lips, mouth, or anus of both men and women. You usually get syphilis from sexual contact with someone who has it. It can also pass from mother to baby during pregnancy.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A52.74 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
095.2 Syphilitic peritonitis
Approximate The match is approximate rather than exact.
ICD-9-CM
095.3 Syphilis of liver
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About A52.74Overview

Is A52.74 (Other symptomatic late syphilis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report syphilis of liver and other viscera on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does A52.74 group to?

When syphilis of liver and other viscera is the principal diagnosis on an inpatient stay, it groups to MS-DRG 441, 442, 443, with relative weights from 0.6997 to 1.7947 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of A52.74?

Under the General Equivalence Mappings, syphilis of liver and other viscera converts to ICD-9-CM 095.2 (syphilitic peritonitis) and 095.3 (syphilis of liver). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.