2027 ICD-10-CM Diagnosis Code A52.14Late syphilitic encephalitis

ICD-10-CM Codes›A00–B99›A50-A64›A52

ICD-10-CM A52.14
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

A52.14 is a billable ICD-10-CM diagnosis code for late syphilitic encephalitis. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 23 through 24, 97 through 99. As a secondary diagnosis, it counts as a major complication or comorbidity (MCC) and places an inpatient stay in the highest severity level of its MS-DRG family. It does not count, however, when the principal diagnosis is one of 96 closely related codes. Coders also document this condition as bacterial meningomyelitis. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Encephalitis and Sexually transmitted infections (excluding HIV and hepatitis).

Code Identity

ICD-10-CM Code
A52.14
Billable Status
Yes — Valid for Submission
Code Describes
Late syphilitic encephalitis
Short Description
Late syphilitic encephalitis
Same as the full description in the CMS dataset.
Parent Code
Symptomatic neurosyphilis

Code Classification

ChapterA00–B99Certain infectious and parasitic diseases
SectionA50-A64Infections with a predominantly sexual mode of transmission
CategoryA52Late syphilis
This CodeA52.14Late syphilitic encephalitis

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Bacterial meningomyelitis
  • Late quaternary neurosyphilis
  • Late syphilitic encephalitis
  • Meningitis caused by Spirochaetes
  • Meningomyelitis
  • Meningomyelitis caused by Treponema pallidum
  • Myelitis caused by bacterium
  • Myelitis caused by Treponema pallidum
  • Syphilitic encephalitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to A52.14: its own notes plus those printed at block A50-A64 and Chapter 1. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • diseases generally recognized as communicable or transmissible

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block A50-A64 Infections with a predominantly sexual mode of transmission applies to 142 codes
  • nonspecific and nongonococcal urethritis (N34.1)
  • Reiter's disease (M02.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block A50-A64 Infections with a predominantly sexual mode of transmission applies to 142 codes
  • human immunodeficiency virus [HIV] disease (B20)
From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • carrier or suspected carrier of infectious disease (Z22.-)
  • certain localized infections - see body system-related chapters
  • infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
  • infectious and parasitic diseases specific to the perinatal period (P35-P39)
  • influenza and other acute respiratory infections (J00-J22)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Chapter 1 (A00-B99) Certain infectious and parasitic diseases applies to 1,068 codes
  • code to identify resistance to antimicrobial drugs (Z16.-)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name A52.14, its category, or a range that includes it.

Applicable To 1

These notes mention A52.14.

  • O98.1 Syphilis complicating pregnancy, childbirth and the puerperium
    Conditions in A50-A53 names A50-A53, which includes this code

Excludes1 1

These codes carry an Excludes1 note naming A52.14: they are not reported together with it, unless the two conditions are unrelated.

  • G99.8 Other specified disorders of nervous system in diseases classified elsewhere
    syphilis (A52.1-) names A52.1-, which includes this code

Excludes2 1

These codes carry an Excludes2 note naming A52.14: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block A65-A69 Other spirochetal diseases
    syphilis (A50-A53) names A50-A53, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS002
Encephalitis
Default principal diagnosis: inpatient No · outpatient No
CCSR INF010
Sexually transmitted infections (excluding HIV and hepatitis)
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Tertiary Syphilis

    a stage of syphilis that occurs fifteen to thirty years after the initial infection; it can include gumma formation and cardiovascular or central nervous system involvement (neurosyphilis).

Patient EducationClinical

Encephalitis

Encephalitis is inflammation (swelling) of the brain. It can happen when an infection or medical condition that affects the brain activates your immune system. The inflammation can cause a wide range of symptoms. In extreme cases, it can lead to brain damage, stroke, or even death.

The full article covers:

  • What is encephalitis?
  • What causes encephalitis?
  • Who is more likely to get encephalitis?
  • What are the symptoms of encephalitis?
  • How is encephalitis diagnosed?
  • What are the treatments for encephalitis?
  • Can encephalitis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert A52.14 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
094.81 Syphilitic encephalitis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About A52.14Overview

What is the ICD-10 code for late syphilitic encephalitis?

The ICD-10-CM code for late syphilitic encephalitis is A52.14 (sometimes written as A5214). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is A52.14 (Symptomatic neurosyphilis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report late syphilitic encephalitis on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does A52.14 group to?

When late syphilitic encephalitis is the principal diagnosis on an inpatient stay, it groups to MS-DRG 24, 98, 99, 23, 97, with relative weights from 1.5249 to 5.7422 depending on complications. Higher weights mean higher Medicare reimbursement.

Is A52.14 a CC or MCC?

CMS lists A52.14 as an MCC (major complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it places the inpatient stay in the highest-weighted DRG of its severity family. It does not count when the principal diagnosis is one of the 96 closely related codes in its exclusion list.

Can A52.14 be reported with N34.1?

Not as a rule. The Excludes1 note at block A50-A64, which applies to A52.14, lists "nonspecific and nongonococcal urethritis (N34.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).