2026 ICD-10-CM Diagnosis Code Z84.81Family history of carrier of genetic disease

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z84

ICD-10-CM Z84.81
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z84.81 is a billable ICD-10-CM diagnosis code for family history of carrier of genetic disease. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. Coders also document this condition as family history of breast cancer 1 gene mutation. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.

Code Identity

ICD-10-CM Code
Z84.81
Billable Status
Yes — Valid for Submission
Code Describes
Family history of carrier of genetic disease
Short Description
Family history of carrier of genetic disease
Same as the full description in the CMS dataset.
Parent Code
Z84.8
Family history of other specified conditions

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ84Family history of other conditions
This CodeZ84.81Family history of carrier of genetic disease

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z84.81.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z84.81 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Family history of breast cancer 1 gene mutation
  • Family history of breast cancer 2 gene mutation
  • Family history of breast cancer gene BRCA mutation
  • Family history of breast cancer gene mutation in first degree relative
  • Family history of gene mutation
  • Family history of genetic disorder carrier
  • Family history of genetic mutation for hereditary nonpolyposis colon cancer
  • Family history of genetic mutation for Lynch syndrome
  • Family history of hereditary disease
  • Family history of hereditary disease carrier state

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • History
      • family (of)
        • carrier of genetic disease
    • History
      • family (of)
        • genetic disease carrier

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC028
Family history of disease
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Family History

Your family history includes health information about you and your close relatives. Families have many factors in common, including their genes, environment, and lifestyle. Looking at these factors can help you figure out whether you have a higher risk for certain health problems, such as heart disease, stroke, and cancer.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z84.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V18.9 Fam hx genet dis carrier
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z84.81Overview

Is Z84.81 (Family history of other specified conditions) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report family history of carrier of genetic disease on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z84.81 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of carrier of genetic disease describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z84.81 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of carrier of genetic disease on inpatient claims.

What is the ICD-9 equivalent of Z84.81?

Under the General Equivalence Mappings, family history of carrier of genetic disease converts to ICD-9-CM V18.9 (fam hx genet dis carrier). The mapping is approximate, so confirm the match fits the documentation.