2027 ICD-10-CM Diagnosis Code Z84.11Family history of APOL1-mediated kidney disease [AMKD]

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z84

ICD-10-CM Z84.11
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Z84.11 is a billable ICD-10-CM diagnosis code for family history of APOL1-mediated kidney disease [AMKD]. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.

Code Identity

ICD-10-CM Code
Z84.11
Billable Status
Yes — Valid for Submission
Code Describes
Family history of APOL1-mediated kidney disease [AMKD]
Short Description
Family history of APOL1-mediated kidney disease [AMKD]
Same as the full description in the CMS dataset.
Parent Code
Z84.1
Family history of disorders of kidney and ureter

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ84Family history of other conditions
This CodeZ84.11Family history of APOL1-mediated kidney disease [AMKD]

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z84.11.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z84.11 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99).

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Z84.11: its own notes plus those printed at block Z77-Z99 and Chapter 21. A note printed at a category, block or chapter applies to every code under it.

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

From Block Z77-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status applies to 567 codes
  • any follow-up examination (Z08-Z09)

Notes

General instructions on how these codes are used.

From Chapter 21 (Z00-Z99) Factors influencing health status and contact with health services applies to 1,425 codes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Z84.11, its category, or a range that includes it.

Use Additional Code 1

These codes say to use an additional code from the note, and Z84.11 is one of the codes named.

  • Z15 Genetic susceptibility to disease
    code, if applicable, for any associated family history of the disease (Z80-Z84) names Z80-Z84, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC028
Family history of disease
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Family History

Your family history includes health information about you and your close relatives. Families have many factors in common, including their genes, environment, and lifestyle. Looking at these factors can help you figure out whether you have a higher risk for certain health problems, such as heart disease, stroke, and cancer.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement Z84.11 replaces the following previously assigned code(s):

  • Z84.1 - Family history of disorders of kidney and ureter
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Z84.11Overview

What is the ICD-10 code for family history of APOL1-mediated kidney disease [AMKD]?

The ICD-10-CM code for family history of APOL1-mediated kidney disease [AMKD] is Z84.11 (sometimes written as Z8411). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is Z84.11 (Family history of disorders of kidney and ureter) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report family history of APOL1-mediated kidney disease [AMKD] on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does Z84.11 group to?

On inpatient claims, family history of APOL1-mediated kidney disease [AMKD] maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can Z84.11 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of APOL1-mediated kidney disease [AMKD] describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z84.11 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of APOL1-mediated kidney disease [AMKD] on inpatient claims. The code appears in the Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99) range of the CMS exempt list.