2026 ICD-10-CM Diagnosis Code Z83.49Family history of other endocrine, nutritional and metabolic diseases
Z83.49 is a billable ICD-10-CM diagnosis code for family history of other endocrine, nutritional and metabolic diseases. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for Z83.49.
Present on Admission (POA)Billing
Z83.49 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Family history of 5,10 methylenetetrahydrofolate reductase deficiency
- Family history of acetylcholinesterase deficiency
- Family history of Addison disease
- Family history of alpha-1-antitrypsin deficiency
- Family history of butyrylcholinesterase deficiency
- Family history of Canavan disease
- Family history of combined hyperlipidemia
- Family history of cystic fibrosis
- Family history of disorder of lung
- Family history of endocrine disorders
- Family history of eruptive xanthoma
- Family history of galactosemia
- Family history of glycogen storage disease
- Family history of Graves disease
- Family history of Hashimoto thyroiditis
- Family history of hemochromatosis
- Family history of hyperbetalipoproteinemia
- Family history of hyperlipidemia
- Family history of hyperparathyroidism
- Family history of hyperthyroidism
- Family history of hypertriglyceridemia
- Family history of hypoalphalipoproteinemia
- Family history of impaired glucose tolerance
- Family history of lysosomal storage disease
- Family history of metabolic disorder
- Family history of methylmalonic aciduria
- Family history of mitochondrial disease
- Family history of movement disorder
- Family history of neuropathy
- Family history of nutritional disorder
- Family history of phenylketonuria
- Family history of polycystic ovary
- Family history of tall stature
- Family history of Tay-Sachs disease
- Family history of tuberous xanthoma
- Family history of vitamin B12 deficiency
- Family history of vitamin D deficiency
- Family history of Wilson disease
- FH: Gout
- FH: Hypercholesterolemia
- FH: Hypercholesterolemia in first degree relative
- FH: Hypothyroidism
- FH: Liver disease
- FH: Nutritional deficiency
- FH: Obesity
- FH: Porphyria
- FH: Raised blood lipids
- FH: Thyroid disorder
- Maternal nutritional disorder
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- History
- family (of) - See Also: History, personal (of);
- endocrine NEC - Z83.49
- metabolic - Z83.49
- nutritional - Z83.49
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- History
- family (of)
- disease or disorder (of)
- endocrine NEC
- History
- family (of)
- disease or disorder (of)
- metabolic
- History
- family (of)
- disease or disorder (of)
- nutritional
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Endocrine Diseases
Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Z83.49 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Z83.49Overview
Is Z83.49 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report family history of other endocrine, nutritional and metabolic diseases on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Can Z83.49 be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of other endocrine, nutritional and metabolic diseases describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is Z83.49 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of other endocrine, nutritional and metabolic diseases on inpatient claims.
What is the ICD-9 equivalent of Z83.49?
Under the General Equivalence Mappings, family history of other endocrine, nutritional and metabolic diseases converts to ICD-9-CM V18.19 (fm hx endo/metab dis NEC). The mapping is approximate, so confirm the match fits the documentation.
