2027 ICD-10-CM Diagnosis Code Z83.49Family history of other endocrine, nutritional and metabolic diseases
Z83.49 is a billable ICD-10-CM diagnosis code for family history of other endocrine, nutritional and metabolic diseases. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 795, 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for Z83.49.
Present on Admission (POA)Billing
Z83.49 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Family history of 5,10 methylenetetrahydrofolate reductase deficiency
- Family history of acetylcholinesterase deficiency
- Family history of Addison disease
- Family history of alpha-1-antitrypsin deficiency
- Family history of butyrylcholinesterase deficiency
- Family history of Canavan disease
- Family history of combined hyperlipidemia
- Family history of cystic fibrosis
- Family history of disorder of lung
- Family history of endocrine disorders
- Family history of eruptive xanthoma
- Family history of galactosemia
- Family history of glycogen storage disease
- Family history of Graves disease
- Family history of Hashimoto thyroiditis
- Family history of hemochromatosis
- Family history of hyperbetalipoproteinemia
- Family history of hyperlipidemia
- Family history of hyperparathyroidism
- Family history of hyperthyroidism
- Family history of hypertriglyceridemia
- Family history of hypoalphalipoproteinemia
- Family history of impaired glucose tolerance
- Family history of lysosomal storage disease
- Family history of metabolic disorder
- Family history of methylmalonic aciduria
- Family history of mitochondrial disease
- Family history of movement disorder
- Family history of neuropathy
- Family history of nutritional disorder
- Family history of phenylketonuria
- Family history of polycystic ovary
- Family history of tall stature
- Family history of Tay-Sachs disease
- Family history of tuberous xanthoma
- Family history of vitamin B12 deficiency
- Family history of vitamin D deficiency
- Family history of Wilson disease
- FH: Gout
- FH: Hypercholesterolemia
- FH: Hypercholesterolemia in first degree relative
- FH: Hypothyroidism
- FH: Liver disease
- FH: Nutritional deficiency
- FH: Obesity
- FH: Porphyria
- FH: Raised blood lipids
- FH: Thyroid disorder
- Maternal nutritional disorder
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to Z83.49: its own notes plus those printed at Z83, block Z77-Z99, and Chapter 21. A note printed at a category, block or chapter applies to every code under it.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
Code Also
A second code may be needed to fully describe the condition; the note gives no sequencing direction.
Notes
General instructions on how these codes are used.
- Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
- (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
- (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name Z83.49, its category, or a range that includes it.
Use Additional Code 1
These codes say to use an additional code from the note, and Z83.49 is one of the codes named.
- Z15 Genetic susceptibility to disease
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
family (of) See Also: History, personal (of);
endocrine NEC Z83.49
metabolic Z83.49
nutritional Z83.49
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Endocrine Diseases
Your endocrine system includes eight major glands throughout your body. These glands make hormones. Hormones are chemical messengers. They travel through your bloodstream to tissues or organs. Hormones work slowly and affect body processes from head to toe. These include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Z83.49 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Z83.49Overview
What is the ICD-10 code for family history of other endocrine, nutritional and metabolic diseases?
The ICD-10-CM code for family history of other endocrine, nutritional and metabolic diseases is Z83.49 (sometimes written as Z8349). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is Z83.49 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report family history of other endocrine, nutritional and metabolic diseases on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does Z83.49 group to?
On inpatient claims, family history of other endocrine, nutritional and metabolic diseases maps to MS-DRG 951, 795, with relative weights from 0.2022 to 0.5574 depending on complications. Higher weights mean higher Medicare reimbursement.
Can Z83.49 be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of other endocrine, nutritional and metabolic diseases describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is Z83.49 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of other endocrine, nutritional and metabolic diseases on inpatient claims. The code appears in the Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99) range of the CMS exempt list.
