2026 ICD-10-CM Diagnosis Code Z80.0Family history of malignant neoplasm of digestive organs

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z80

ICD-10-CM Z80.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z80.0 is a billable ICD-10-CM diagnosis code for family history of malignant neoplasm of digestive organs. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.

Code Identity

ICD-10-CM Code
Z80.0
Billable Status
Yes — Valid for Submission
Code Describes
Family history of malignant neoplasm of digestive organs
Short Description
Family history of malignant neoplasm of digestive organs
Same as the full description in the CMS dataset.
Parent Code
Z80
Family history of primary malignant neoplasm

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ80Family history of primary malignant neoplasm
This CodeZ80.0Family history of malignant neoplasm of digestive organs

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z80.0.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z80.0 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Family history of cancer of colon
  • Family history of cancer of the esophagus
  • Family history of carcinoma of esophagus
  • Family history of colorectal cancer
  • Family history of disorder of pancreas
  • Family history of hepatoma
  • Family history of hereditary diffuse gastric cancer
  • Family history of hereditary nonpolyposis colon cancer
  • Family history of malignant epithelial neoplasm
  • Family history of malignant neoplasm of biliary tract
  • Family history of malignant neoplasm of colon over age 50
  • Family history of malignant neoplasm of digestive organ
  • Family history of malignant neoplasm of gastrointestinal tract
  • Family history of malignant neoplasm of ileum
  • Family history of malignant neoplasm of liver
  • Family history of malignant neoplasm of pancreas
  • Family history of malignant neoplasm of pharynx
  • Family history of malignant tumor of rectum
  • Family history of neoplasm of upper aerodigestive tract
  • FH: Biliary disease
  • FH: Bowel cancer
  • FH: Liver disease
  • FH: Stomach cancer

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Conditions classifiable to C15 C26

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • History
      • family (of)
        • malignant neoplasm (of) NOS
          • digestive organ
    • History
      • family (of)
        • malignant neoplasm (of) NOS
          • gastrointestinal tract

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC028
Family history of disease
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Cancer

Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should.

The full article covers:

  • What is cancer?
  • What are the types of cancer?
  • How does cancer develop?
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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z80.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V16.0 Family hx-gi malignancy
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z80.0Overview

Is Z80.0 (Family history of primary malignant neoplasm) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report family history of malignant neoplasm of digestive organs on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z80.0 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of malignant neoplasm of digestive organs describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z80.0 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of malignant neoplasm of digestive organs on inpatient claims.

What is the ICD-9 equivalent of Z80.0?

Under the General Equivalence Mappings, family history of malignant neoplasm of digestive organs converts to ICD-9-CM V16.0 (family hx-gi malignancy). The mapping is a direct match.