2027 ICD-10-CM Diagnosis Code Z80.0Family history of malignant neoplasm of digestive organs

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z80

ICD-10-CM Z80.0
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Z80.0 is a billable ICD-10-CM diagnosis code for family history of malignant neoplasm of digestive organs. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.

Code Identity

ICD-10-CM Code
Z80.0
Billable Status
Yes — Valid for Submission
Code Describes
Family history of malignant neoplasm of digestive organs
Short Description
Family history of malignant neoplasm of digestive organs
Same as the full description in the CMS dataset.
Parent Code
Family history of primary malignant neoplasm

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ80Family history of primary malignant neoplasm
This CodeZ80.0Family history of malignant neoplasm of digestive organs

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z80.0.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Family history of cancer of colon
  • Family history of cancer of the esophagus
  • Family history of carcinoma of esophagus
  • Family history of colorectal cancer
  • Family history of disorder of pancreas
  • Family history of hepatoma
  • Family history of hereditary diffuse gastric cancer
  • Family history of hereditary nonpolyposis colon cancer
  • Family history of malignant epithelial neoplasm
  • Family history of malignant neoplasm of biliary tract
  • Family history of malignant neoplasm of colon over age 50
  • Family history of malignant neoplasm of digestive organ
  • Family history of malignant neoplasm of gastrointestinal tract
  • Family history of malignant neoplasm of ileum
  • Family history of malignant neoplasm of liver
  • Family history of malignant neoplasm of pancreas
  • Family history of malignant neoplasm of pharynx
  • Family history of malignant tumor of rectum
  • Family history of neoplasm of upper aerodigestive tract
  • FH: Biliary disease
  • FH: Bowel cancer
  • FH: Liver disease
  • FH: Stomach cancer

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Z80.0: its own notes plus those printed at block Z77-Z99 and Chapter 21. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Conditions classifiable to C15-C26

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

From Block Z77-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status applies to 567 codes
  • any follow-up examination (Z08-Z09)

Notes

General instructions on how these codes are used.

From Chapter 21 (Z00-Z99) Factors influencing health status and contact with health services applies to 1,425 codes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Z80.0, its category, or a range that includes it.

Excludes2 1

These codes carry an Excludes2 note naming Z80.0: its condition is not part of those codes, and both may be reported when the patient has both.

  • Z83.71 Family history of colonic polyps
    family history of malignant neoplasm of digestive organs (Z80.0)

Use Additional Code 2

These codes say to use an additional code from the note, and Z80.0 is one of the codes named.

  • Z12 Encounter for screening for malignant neoplasms
    code to identify any family history of malignant neoplasm (Z80.-) names Z80.-, which includes this code
  • Z15 Genetic susceptibility to disease
    code, if applicable, for any associated family history of the disease (Z80-Z84) names Z80-Z84, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC028
Family history of disease
Default principal diagnosis: inpatient No · outpatient Yes

Patient EducationClinical

Cancer

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The full article covers:

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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z80.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V16.0 Family hx-gi malignancy
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Z80.0Overview

What is the ICD-10 code for family history of malignant neoplasm of digestive organs?

The ICD-10-CM code for family history of malignant neoplasm of digestive organs is Z80.0 (sometimes written as Z800). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is Z80.0 (Family history of primary malignant neoplasm) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report family history of malignant neoplasm of digestive organs on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does Z80.0 group to?

On inpatient claims, family history of malignant neoplasm of digestive organs maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can Z80.0 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of malignant neoplasm of digestive organs describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z80.0 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of malignant neoplasm of digestive organs on inpatient claims. The code appears in the Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99) range of the CMS exempt list.