2027 ICD-10-CM Diagnosis Code R77.2Abnormality of alphafetoprotein
ICD-10-CM Codes›R00–R99›R70-R79›R77
- Billable — Valid for Submission
- Not Chronic
R77.2 is a billable ICD-10-CM diagnosis code for abnormality of alphafetoprotein. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 947 through 948. As a symptom code, it should not be used as a principal diagnosis once a related definitive diagnosis has been established. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Abnormal findings without diagnosis.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Abnormal presence of alpha-fetoprotein
- Abnormal presence of protein
- Abnormal structure of alpha-fetoprotein
- Abnormal structure of physiologic substance
- Alpha-fetoprotein above reference range
- Alpha-fetoprotein below reference range
- Alpha-fetoprotein equivocal
- Congenital deficiency of alpha-fetoprotein
- Finding related to physiologic substance
- Hereditary persistence of alpha-fetoprotein
- Serum alpha-fetoprotein level - finding
- Serum alpha-fetoprotein level above reference range
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to R77.2: its own notes plus those printed at R77, block R70-R79, and Chapter 18. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- abnormal findings on antenatal screening of mother (O28.-)
- abnormalities of lipids (E78.-)
- abnormalities of platelets and thrombocytes (D69.-)
- abnormalities of white blood cells classified elsewhere (D70-D72)
- coagulation hemorrhagic disorders (D65-D68)
- diagnostic abnormal findings classified elsewhere - see Alphabetical Index
- hemorrhagic and hematological disorders of newborn (P50-P61)
Notes
General instructions on how these codes are used.
- This chapter includes symptoms, signs, abnormal results of clinical or other investigative procedures, and ill-defined conditions regarding which no diagnosis classifiable elsewhere is recorded.
- Signs and symptoms that point rather definitely to a given diagnosis have been assigned to a category in other chapters of the classification. In general, categories in this chapter include the less well-defined conditions and symptoms that, without the necessary study of the case to establish a final diagnosis, point perhaps equally to two or more diseases or to two or more systems of the body. Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'. The Alphabetical Index should be consulted to determine which symptoms and signs are to be allocated here and which to other chapters. The residual subcategories, numbered .8, are generally provided for other relevant symptoms that cannot be allocated elsewhere in the classification.
- The conditions and signs or symptoms included in categories R00-R94 consist of:
- (a) cases for which no more specific diagnosis can be made even after all the facts bearing on the case have been investigated;
- (b) signs or symptoms existing at the time of initial encounter that proved to be transient and whose causes could not be determined;
- (c) provisional diagnosis in a patient who failed to return for further investigation or care;
- (d) cases referred elsewhere for investigation or treatment before the diagnosis was made;
- (e) cases in which a more precise diagnosis was not available for any other reason;
- (f) certain symptoms, for which supplementary information is provided, that represent important problems in medical care in their own right.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name R77.2, its category, or a range that includes it.
Excludes2 1
These codes carry an Excludes2 note naming R77.2: its condition is not part of those codes, and both may be reported when the patient has both.
- Block R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Abnormal, abnormality, abnormalities See Also: Anomaly;
alphafetoprotein R77.2
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Blood
Your blood is made up of liquid and solids. The liquid part, called plasma, is made of water, salts, and protein. Over half of your blood is plasma. The solid part of your blood contains red blood cells, white blood cells, and platelets.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert R77.2 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About R77.2Overview
What is the ICD-10 code for abnormality of alphafetoprotein?
The ICD-10-CM code for abnormality of alphafetoprotein is R77.2 (sometimes written as R772). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is R77.2 (Other abnormalities of plasma proteins) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report abnormality of alphafetoprotein on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does R77.2 group to?
When abnormality of alphafetoprotein is the principal diagnosis on an inpatient stay, it groups to MS-DRG 948, 947, with relative weights from 0.7833 to 1.2608 depending on complications. Higher weights mean higher Medicare reimbursement.
Can R77.2 be a principal diagnosis?
Use it with care. This is a symptom code, so once a definitive diagnosis explaining the abnormality of alphafetoprotein is established, that condition takes the principal position instead.
Can R77.2 be reported with a code from E88.0?
Not as a rule. The Excludes1 note at R77, which applies to R77.2, lists "disorders of plasma-protein metabolism (E88.0-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
