2027 ICD-10-CM Diagnosis Code Q96.3Mosaicism, 45, X/46, XX or XY
ICD-10-CM Codes›Q00-Q99›Q90-Q99›Q96
- Billable — Valid for Submission
- POA Exempt
- Chronic Condition
Q96.3 is a billable ICD-10-CM diagnosis code for mosaicism, 45, X/46, XX or XY. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 742 through 743, 760 through 761. The code is exempt from POA reporting. Coders also document this condition as genetic mosaic. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Chromosomal abnormalities.
Code Identity
Code Classification
Present on Admission (POA)Billing
Q96.3 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review the other POA exempt codes in Chromosomal abnormalities, not elsewhere classified (Q90-Q99).
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Genetic mosaic
- Mosaic Turner syndrome
- Mosaic XO/XX
- Mosaic XO/XY
- Mosaicism 45, X; 46, XX
- Sex chromosome mosaicism
- Turner syndrome
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to Q96.3: its own notes plus those printed at Q96, block Q90-Q99, and Chapter 17. A note printed at a category, block or chapter applies to every code under it.
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- mitochondrial metabolic disorders (E88.4-)
Notes
General instructions on how these codes are used.
- Codes from this chapter are not for use on maternal records
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name Q96.3, its category, or a range that includes it.
Excludes1 7
These codes carry an Excludes1 note naming Q96.3: they are not reported together with it, unless the two conditions are unrelated.
- E28.3 Primary ovarian failureTurner's syndrome (Q96.-) names Q96.-, which includes this code
- Q50.0 Congenital absence of ovaryTurner's syndrome (Q96.-) names Q96.-, which includes this code
- Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classifiedTurner's syndrome (Q96.-) names Q96.-, which includes this code
- E25 Adrenogenital disorders
- Block Q50-Q56 Congenital malformations of genital organs
- Q56 Indeterminate sex and pseudohermaphroditism
- Z15 Genetic susceptibility to disease
Code First 1
These codes say to code first a condition named in the note, and Q96.3 is one of the conditions named.
- D84.81 Immunodeficiency due to conditions classified elsewhere
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Mosaicism, mosaic (autosomal) (chromosomal)
45,X/46,XX Q96.3
XY Q96.3
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Turner Syndrome
a syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,x (or 45,xo). patients generally are of short stature with undifferentiated gonads (streak gonads), sexual infantilism, hypogonadism, webbing of the neck, cubitus valgus, elevated gonadotropins, decreased estradiol level in blood, and congenital heart defects. noonan syndrome (also called pseudo-turner syndrome and male turner syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
Patient EducationClinical
Turner Syndrome
Turner syndrome is a genetic disorder that affects a girl's development and appearance. It can also cause health problems such as infertility and heart problems.
The full article covers:
- What is Turner syndrome?
- What causes Turner syndrome?
- What are the symptoms of Turner syndrome?
- How is Turner syndrome diagnosed?
- What are the treatments for Turner syndrome?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Q96.3 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Q96.3Overview
What is the ICD-10 code for mosaicism, 45, X/46, XX or XY?
The ICD-10-CM code for mosaicism, 45, X/46, XX or XY is Q96.3 (sometimes written as Q963). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is Q96.3 (Turner's syndrome) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report mosaicism, 45, X/46, XX or XY on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does Q96.3 group to?
When mosaicism, 45, X/46, XX or XY is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.7039 to 1.8448 depending on complications. Higher weights mean higher Medicare reimbursement.
Is Q96.3 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for mosaicism, 45, X/46, XX or XY on inpatient claims. The code appears in the Chromosomal abnormalities, not elsewhere classified (Q90-Q99) range of the CMS exempt list.
Can Q96.3 be reported with Q87.19?
Not as a rule. The Excludes1 note at Q96, which applies to Q96.3, lists "Noonan syndrome (Q87.19)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
