2026 ICD-10-CM Diagnosis Code Q96.2Karyotype 46, X with abnormal sex chromosome, except iso (Xq)
ICD-10-CM Codes›Q00-Q99›Q90-Q99›Q96
- Billable — Valid for Submission
- POA Exempt
- Chronic Condition
Q96.2 is a billable ICD-10-CM diagnosis code for karyotype 46, X with abnormal sex chromosome, except iso (Xq). It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 742 through 743, 760 through 761. The code is exempt from POA reporting. Coders also document this condition as karyotype 46, X with abnormal sex chromosome except iso. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Chromosomal abnormalities.
Code Identity
Code Classification
Present on Admission (POA)Billing
Q96.2 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Karyotype 46, X with abnormal sex chromosome except iso
- Turner syndrome
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Karyotype 46, X with abnormal sex chromosome, except isochromosome Xq
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- with abnormality except iso (Xq) - Q96.2
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Karyotype
- with abnormality except iso (Xq)
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Noonan Syndrome
a genetically heterogeneous, multifaceted disorder characterized by short stature, webbed neck, ptosis, skeletal malformations, hypertelorism, hormonal imbalance, cryptorchidism, multiple cardiac abnormalities (most commonly including pulmonary valve stenosis), and some degree of intellectual disability. the phenotype bears similarities to that of turner syndrome that occurs only in females and has its basis in a 45, x karyotype abnormality. noonan syndrome occurs in both males and females with a normal karyotype (46,xx and 46,xy). mutations in a several genes (ptpn11, kras, sos1, nf1 and raf1) have been associated the ns phenotype. mutations in ptpn11 are the most common. leopard syndrome, a disorder that has clinical features overlapping those of noonan syndrome, is also due to mutations in ptpn11. in addition, there is overlap with the syndrome called neurofibromatosis-noonan syndrome due to mutations in nf1.Turner Syndrome
a syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,x (or 45,xo). patients generally are of short stature with undifferentiated gonads (streak gonads), sexual infantilism, hypogonadism, webbing of the neck, cubitus valgus, elevated gonadotropins, decreased estradiol level in blood, and congenital heart defects. noonan syndrome (also called pseudo-turner syndrome and male turner syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant.
Patient EducationClinical
Turner Syndrome
Turner syndrome is a genetic disorder that affects a girl's development and appearance. It can also cause health problems such as infertility and heart problems.
The full article covers:
- What is Turner syndrome?
- What causes Turner syndrome?
- What are the symptoms of Turner syndrome?
- How is Turner syndrome diagnosed?
- What are the treatments for Turner syndrome?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Q96.2 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Q96.2Overview
Is Q96.2 (Turner's syndrome) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report karyotype 46, X with abnormal sex chromosome, except iso (Xq) on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does Q96.2 group to?
When karyotype 46, X with abnormal sex chromosome, except iso (Xq) is the principal diagnosis on an inpatient stay, it groups to MS-DRG 742, 743, 760, 761, with relative weights from 0.5696 to 1.8348 depending on complications. Higher weights mean higher Medicare reimbursement.
Is Q96.2 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for karyotype 46, X with abnormal sex chromosome, except iso (Xq) on inpatient claims.
What is the ICD-9 equivalent of Q96.2?
Under the General Equivalence Mappings, karyotype 46, X with abnormal sex chromosome, except iso (Xq) converts to ICD-9-CM 758.6 (gonadal dysgenesis). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
