2026 ICD-10-CM Diagnosis Code Q93.88Other microdeletions

ICD-10-CM Codes›Q00-Q99›Q90-Q99›Q93

ICD-10-CM Q93.88
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q93.88 is a billable ICD-10-CM diagnosis code for other microdeletions. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Chromosomal abnormalities.

Code Identity

ICD-10-CM Code
Q93.88
Billable Status
Yes — Valid for Submission
Code Describes
Other microdeletions
Short Description
Other microdeletions
Same as the full description in the CMS dataset.
Parent Code
Q93.8
Other deletions from the autosomes

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ90-Q99Chromosomal abnormalities, not elsewhere classified
CategoryQ93Monosomies and deletions from the autosomes, not elsewhere classified
This CodeQ93.88Other microdeletions

Present on Admission (POA)Billing

Q93.88 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • 10p partial monosomy syndrome
  • 10q partial monosomy
  • 10q22.3q23.3 microdeletion syndrome
  • 11q partial monosomy syndrome
  • 11q22.2q22.3 microdeletion syndrome
  • 12p12.1 microdeletion syndrome
  • 12q14 microdeletion syndrome
  • 12q15q21.1 microdeletion syndrome
  • 13q12.3 microdeletion syndrome
  • 14q11.2 microdeletion syndrome
  • 14q12 microdeletion syndrome
  • 14q22q23 microdeletion syndrome
  • 14q24.1q24.3 microdeletion syndrome
  • 15q11.2 microdeletion syndrome
  • 15q13.3 microdeletion
  • 15q14 microdeletion syndrome
  • 15q24 microdeletion
  • 16p11.2p12.2 microdeletion syndrome
  • 16p12.2 microdeletion syndrome
  • 16p13.11 microduplication syndrome
  • 16q24.1 microdeletion syndrome
  • 17q12 microdeletion syndrome
  • 17q23.1q23.2 microdeletion syndrome
  • 17q24.2 microdeletion syndrome
  • 19p13.12 microdeletion syndrome
  • 19p13.13 microdeletion syndrome
  • 1p partial monosomy
  • 1p31p32 microdeletion syndrome
  • 1p35.2 microdeletion syndrome
  • 1q partial monosomy
  • 1q21.1 microdeletion
  • 1q41q42 microdeletion syndrome
  • 1q44 microdeletion syndrome
  • 20p12.3 microdeletion syndrome
  • 20p13 microdeletion syndrome
  • 20q11.2 microdeletion syndrome
  • 20q13.33 microdeletion syndrome
  • 21q partial monosomy syndrome
  • 21q22.11q22.12 microdeletion syndrome
  • 22q partial monosomy
  • 2p13.2 microdeletion syndrome
  • 2p15p16.1 microdeletion syndrome
  • 2p21 microdeletion syndrome
  • 2p21 microdeletion syndrome without cystinuria
  • 2q23.1 microdeletion syndrome
  • 2q24 microdeletion syndrome
  • 2q31.1 microdeletion syndrome
  • 2q32q33 microdeletion syndrome
  • 2q33.1 microdeletion syndrome
  • 3q13 microdeletion syndrome
  • 3q29 microdeletion syndrome
  • 5q14.3 microdeletion syndrome
  • 5q31.3 microdeletion syndrome
  • 6p22 microdeletion syndrome
  • 6q16 microdeletion syndrome
  • 7q partial monosomy
  • 7q31 microdeletion syndrome
  • 8p partial monosomy syndrome
  • 8p23.1 microdeletion syndrome
  • 8q partial monosomy syndrome
  • 8q13 microdeletion syndrome
  • 8q22.1 microdeletion syndrome
  • 8q24.3 microdeletion syndrome
  • 9p13 microdeletion syndrome
  • 9q partial monosomy syndrome
  • 9q21.13 microdeletion syndrome
  • 9q31.1q31.3 microdeletion syndrome
  • 9q33.3q34.11 microdeletion syndrome
  • Chromosome microdeletion
  • Chromosome Xp11.3 microdeletion syndrome
  • Chromosome Xp22.3 microdeletion syndrome
  • Cystinuria
  • Cystinuria, type 1
  • Deletion of long arm of chromosome 13
  • Deletion of part of chromosome 10
  • Deletion of part of chromosome 11
  • Deletion of part of chromosome 13
  • Deletion of part of chromosome 14
  • Deletion of part of chromosome 15
  • Deletion of part of chromosome 17
  • Deletion of part of chromosome 19
  • Deletion of part of chromosome 20
  • Deletion of part of chromosome 21
  • Deletion of part of chromosome 22
  • Deletion of part of chromosome 5
  • Deletion of part of chromosome 6
  • Deletion of part of long arm of chromosome 12
  • Deletion of part of long arm of chromosome 17
  • Deletion of part of long arm of chromosome 2
  • Deletion of part of long arm of chromosome 20
  • Deletion of part of long arm of chromosome 3
  • Deletion of part of long arm of chromosome 5
  • Deletion of part of long arm of chromosome 6
  • Deletion of part of short arm of chromosome 12
  • Deletion of part of short arm of chromosome 16
  • Deletion of part of short arm of chromosome 17
  • Deletion of part of short arm of chromosome 2
  • Deletion of part of short arm of chromosome 20
  • Deletion of part of short arm of chromosome 6
  • Deletion of short arm of chromosome 19
  • Distal 16p11.2 microdeletion syndrome
  • Distal 17p13.1 microdeletion syndrome
  • Distal 17p13.3 microdeletion syndrome
  • Distal 22q11.2 microdeletion syndrome
  • Distal 7q11.23 microdeletion syndrome
  • Distal deletion of long arm of chromosome 7
  • Dominant autosomal hereditary disorder, incomplete penetrance
  • Duplication of part of short arm of chromosome 16
  • DYRK1A-related intellectual disability syndrome
  • DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion
  • Facial dysmorphism, developmental delay, behavioral abnormalities syndrome due to 10p11.21p12.31 microdeletion
  • Hao Fountain syndrome
  • Hao Fountain syndrome due to 16p13.2 microdeletion
  • Lamb Shaffer syndrome
  • Mild intellectual disability
  • Miller Dieker syndrome
  • Mowat-Wilson syndrome
  • Mowat-Wilson syndrome due to monosomy 2q22
  • Osteopoikilosis
  • Partial deletion of long arm of chromosome 14
  • Partial deletion of long arm of chromosome 15
  • Partial deletion of long arm of chromosome 16
  • Partial trisomy of chromosome 16
  • Paternal 14q32.2 microdeletion
  • Paternal 20q13.2q13.3 microdeletion syndrome
  • Prader-Willi-like syndrome
  • Proximal 16p11.2 microdeletion syndrome
  • SATB2-associated syndrome
  • Smith-Magenis syndrome
  • Speech delay
  • Type 1 lissencephaly
  • WAC-related facial dysmorphism, developmental delay, behavioral abnormalities syndrome
  • X-linked retinitis pigmentosa

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Miller-Dieker syndrome
  • Smith-Magenis syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Deletion(s)
      • microdeletions NEC
    • Microdeletions NEC
    • Syndrome
      • Miller-Dieker
    • Syndrome
      • Smith-Magenis

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MAL009
Chromosomal abnormalities
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Cystinuria

    an inherited disorder due to defective reabsorption of cystine and other basic amino acids by the proximal renal tubules. this form of aminoaciduria is characterized by the abnormally high urinary levels of cystine; lysine; arginine; and ornithine. mutations involve the amino acid transport protein gene slc3a1.

  • Osteopoikilosis

    an asymptomatic, autosomal dominant trait in which pea-sized sclerotic spots, prominent in the metaphyseal area, are accompanied by unique cutaneous lesions. these are yellowish papules or plaques with increased elastin content. (from cecil textbook of medicine, 19th ed, pp1434-35)

  • Arakawa Syndrome II|Arakawa's Syndrome 2|Arakawa's Syndrome II|Homocystinuria-Megaloblastic Anemia, cblG Complementation Type|Methionine Synthase Deficiency|Methylcobalamin Deficiency, cblG Type|Tetrahydrofolate Methyltransferase Deficiency|Tetrahydrofolate Methyltransferase Deficiency

    a rare autosomal dominant inherited metabolic disorder characterized by deficiency of the enzyme tetrahydrofolate-methyltransferase. it results in the abnormal metabolism of methylcobalamin. signs and symptoms include mental retardation, megaloblastic anemia, hypotonia, epilepsy, and hepatosplenomegaly.

  • Combined Methylmalonic Aciduria and Homocystinuria|Combined methylmalonic acidemia and homocystinuria due to defects in adenosylcobalamin and methylcobalamin synthesis

    a genetically heterogeneous disorder of cobalamin (cbl; vitamin b12) metabolism due to loss of function mutations in the enzymes that synthesize the coenzymes adenosylcobalamin (adocbl) and methylcobalamin (mecbl). this is a subtype of methylmalonic acidemia that includes complementation groups cblc, cbld, cblf, cblj, cbll and cblx.

  • Cyanocobalamin Reductase / Alkylcobalamin Dealkylase|Alkylcobalamin:Glutathione S-Alkyltransferase|CblC|Cyanocobalamin Reductase (Cyanide-Eliminating)|EC 1.16.1.6|EC 2.5.1.15|MMACHC|Methylmalonic Aciduria and Homocystinuria Type C Protein

    cyanocobalamin reductase / alkylcobalamin dealkylase (282 aa, ~32 kda) is encoded by the human mmachc gene. this protein is involved in cobalamin transport and the decyanation of cyanocob(iii)alamin (cyanocobalamin, cncbl) to yield cob(ii)alamin and cyanide and the dealkylation of alkylcob(iii)alamins using a thiolate of glutathione to generate cob(i)alamin and the corresponding glutathione thioether.

  • Cystinuria

    an autosomal recessive inherited metabolic disorder caused by mutations in the slc3a1 and slc7a9 genes. it is characterized by deficient re-absorption of cystine in the proximal tubules of the kidney. it results in the formation of stones in the kidney, ureter, and urinary bladder.

  • Homocystinuria

    an autosomal recessive inherited metabolic disorder caused by mutations in the cbs, mthfr, mtr, and mtrr genes. it is characterized by abnormalities in the methionine metabolism and is associated with deficiency of cystathionine synthase. it results in the accumulation of homocysteine in the serum. it may affect the cardiovascular, musculoskeletal and the central nervous systems.

  • Homocystinuria-Megaloblastic Anemia, cblE Complementation Type|HMAE|Methylcobalamin Deficiency, cblE Type

    an autosomal recessive condition caused by mutation(s) in the mtrr gene, encoding methionine synthase reductase. it is characterized by homocystinuria and megaloblastic anemia.

  • Methylmalonic Aciduria and Homocystinuria Type D Protein, Mitochondrial|C2orf25 Protein|MMADHC|Methylmalonic Aciduria, cblD Type, And Homocystinuria Protein|Uncharacterized Protein C2orf25, Mitochondrial

    methylmalonic aciduria and homocystinuria type d protein, mitochondrial (296 aa, ~33 kda) is encoded by the human mmadhc gene. this protein plays a role in vitamin metabolism.

  • Methylmalonic Aciduria and Homocystinuria, cblC Type

    an autosomal recessive form of combined methylmalonic aciduria and homocystinuria, caused by mutation(s) in the mmachc gene, encoding methylmalonic aciduria and homocystinuria type c protein.

  • Methylmalonic Aciduria and Homocystinuria, cblD Type|MAHCD

    an autosomal recessive form of combined methylmalonic aciduria and homocystinuria, caused by mutation(s) in the mmadhc gene, encoding cobalamin trafficking protein cbld.

  • Methylmalonic Aciduria and Homocystinuria, cblF Type|MAHCF

    an autosomal recessive form of combined methylmalonic aciduria and homocystinuria, caused by mutation(s) in the lmbrd1 gene, encoding lysosomal cobalamin transport escort protein lmbd1.

  • Methylmalonic Aciduria and Homocystinuria, cblJ Type|MAHCJ

    an autosomal recessive form of combined methylmalonic aciduria and homocystinuria, caused by mutation(s) in the abcd4 gene, encoding lysosomal cobalamin transporter abcd4.

  • MMACHC wt Allele|DKFZP564I122|Metabolism of Cobalamin Associated C wt Allele|Methylmalonic Aciduria (Cobalamin Deficiency) cblC Type, with Homocystinuria Gene|cblC

    human mmachc wild-type allele is located in the vicinity of 1p34.1 and is approximately 13 kb in length. this allele, which encodes cyanocobalamin reductase / alkylcobalamin dealkylase protein, plays a role in cobalamin transport and the conversion of cyanocobalamin and alkylcobalamin to cobalamin. mutation of the gene is associated with methylmalonic aciduria and homocystinuria cblc type.

  • MMADHC Gene|MMADHC|MMADHC|Methylmalonic Aciduria (Cobalamin Deficiency) cblD Type, with Homocystinuria Gene

    this gene is involved in vitamin metabolism.

  • MMADHC wt Allele|C2orf25|CL25022|Chromosome 2 Open Reading Frame 25 Gene|HSPC161|Methylmalonic Aciduria (Cobalamin Deficiency) cblD Type, with Homocystinuria wt Allele|Methylmalonic Aciduria, cblD Type, and Homocystinuria Gene|My011|cblD

    human mmadhc wild-type allele is located in the vicinity of 2q23.2 and is approximately 18 kb in length. this allele, which encodes methylmalonic aciduria and homocystinuria type d protein, mitochondrial, plays a role in the mediation of vitamin b12 metabolism. mutation of the gene is associated with some cases of homocystinuria, and methylmalonic aciduria.

  • Osteopoikilosis

    a rare autosomal dominant inherited disorder characterized by the presence of small areas of increased density throughout the bones.

Patient EducationClinical

Genetic Disorders

Genetic disorders are health conditions caused by changes (also called mutations or variants) in your genes. Genes are parts of DNA found in your cells that carry instructions for how your body grows, develops, and functions. Many genes tell your body how to make proteins, which are needed for your body to work properly.

The full article covers:

  • What are genetic disorders?
  • What causes genetic disorders?
  • What are the types of genetic disorders?
  • What are the different ways a genetic disorder can be inherited?
  • How are genetic disorders diagnosed?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Q93.88 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
758.33 Microdeletions NEC
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Q93.88Overview

Is Q93.88 (Other deletions from the autosomes) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report other microdeletions on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is Q93.88 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for other microdeletions on inpatient claims.

What is the ICD-9 equivalent of Q93.88?

Under the General Equivalence Mappings, other microdeletions converts to ICD-9-CM 758.33 (microdeletions NEC). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.